World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
46
Citations
7724
World Ranking
2811
National Ranking
191

Overview

Chase L. Beisel is affiliated with the University of Würzburg in Germany and has made substantial contributions to the field of Biochemistry, Genetics, and Molecular Biology, with a total of 183 publications. Their work largely focuses on Molecular Biology, reflecting 142 publications in this subfield, alongside contributions to Genetics, Insect Science, Endocrinology, and Ecology.

The primary research topics addressed by Beisel encompass CRISPR and Genetic Engineering, RNA and protein synthesis mechanisms, and Bacterial Genetics and Biotechnology. Additional interests include Insect symbiosis and bacterial influences, Advanced biosensing and bioanalysis techniques, RNA Interference and Gene Delivery, and Innovation and Socioeconomic Development.

Beisel's frequent collaborators include Scott P. Collins, Katharina G. Wandera, Tatjana Achmedov, Yanying Yu, and Lars Barquist, reflecting ongoing partnerships in their research endeavors.

The scientist's work has been published repeatedly in venues such as bioRxiv (Cold Spring Harbor Laboratory) with 21 publications, Molecular Cell (7 publications), Nucleic Acids Research (6 publications), Nature Communications (4 publications), and Methods in Molecular Biology (4 publications).

Notable recent papers include:

  • "CRISPR technologies and the search for the PAM-free nuclease" (2021, Nature Communications)
  • "Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9" (2021, Science)
  • "CRISPR-Cas Systems and the Paradox of Self-Targeting Spacers" (2020, Frontiers in Microbiology)
  • "Competitive Exclusion Is a Major Bioprotective Mechanism of Lactobacilli against Fungal Spoilage in Fermented Milk Products" (2020, Applied and Environmental Microbiology)
  • "The miniature CRISPR-Cas12m effector binds DNA to block transcription" (2022, Molecular Cell)

Best Publications

  • Self‐Assembled DNA Nanoclews for the Efficient Delivery of CRISPR–Cas9 for Genome Editing

    Wujin Sun;Wenyan Ji;Jordan M. Hall;Quanyin Hu

  • Programmable removal of bacterial strains by use of genome-targeting CRISPR-Cas systems.

    Ahmed A. Gomaa;Heidi E. Klumpe;Michelle L. Luo;Kurt Selle

  • Base pairing small RNAs and their roles in global regulatory networks

    Chase L. Beisel;Gisela Storz

  • Guide RNA functional modules direct Cas9 activity and orthogonality.

    Alexandra E. Briner;Paul D. Donohoue;Ahmed A. Gomaa;Kurt Selle

  • Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems.

    Ryan T. Leenay;Kenneth R. Maksimchuk;Rebecca A. Slotkowski;Roma N. Agrawal

  • Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression

    Michelle L. Luo;Adam S. Mullis;Ryan T. Leenay;Chase L. Beisel

  • The base-pairing RNA spot 42 participates in a multioutput feedforward loop to help enact catabolite repression in Escherichia coli.

    Chase L. Beisel;Gisela Storz

  • Rapid and Scalable Characterization of CRISPR Technologies Using an E. coli Cell-Free Transcription-Translation System

    Ryan Marshall;Colin S. Maxwell;Scott P. Collins;Thomas Jacobsen

  • CRISPR technologies and the search for the PAM-free nuclease

    Daphne Collias;Chase L. Beisel;Chase L. Beisel

  • Deciphering, Communicating, and Engineering the CRISPR PAM

    Ryan T. Leenay;Chase L. Beisel

  • Model-guided design of ligand-regulated RNAi for programmable control of gene expression.

    Chase L Beisel;Travis S Bayer;Kevin G Hoff;Christina D Smolke

  • Design principles for riboswitch function.

    Chase L. Beisel;Christina D. Smolke

  • Current and future prospects for CRISPR-based tools in bacteria

    Michelle L. Luo;Ryan T. Leenay;Chase L. Beisel

  • Multiple factors dictate target selection by Hfq‐binding small RNAs

    Chase L Beisel;Taylor B Updegrove;Ben J Janson;Gisela Storz

  • CRISPR RNA-Dependent Binding and Cleavage of Endogenous RNAs by the Campylobacter jejuni Cas9.

    Gaurav Dugar;Ryan T. Leenay;Sara K. Eisenbart;Thorsten Bischler

  • Bacterial Adaptation to the Host's Diet Is a Key Evolutionary Force Shaping Drosophila-Lactobacillus Symbiosis.

    Maria Elena Martino;Pauline Joncour;Ryan Leenay;Hugo Gervais

  • Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing

    Chase L. Beisel;Yvonne Y. Chen;Stephanie J. Culler;Kevin G. Hoff

  • Synthetic control of a fitness tradeoff in yeast nitrogen metabolism.

    Travis S Bayer;Kevin G Hoff;Chase L Beisel;Jack J Lee

  • Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9.

    Chunlei Jiao;Sahil Sharma;Gaurav Dugar;Natalia L. Peeck

  • Synthetic Biology Approaches to Engineer Probiotics and Members of the Human Microbiota for Biomedical Applications

    Josef R. Bober;Chase L. Beisel;Nikhil U. Nair

Frequent Co-Authors

Christina D. Smolke
Christina D. Smolke Stanford University
Rodolphe Barrangou
Rodolphe Barrangou North Carolina State University
Andrea Crisanti
Andrea Crisanti University of Padua
Gisela Storz
Gisela Storz National Institutes of Health
Zhen Gu
Zhen Gu Zhejiang University
Cynthia M. Sharma
Cynthia M. Sharma University of Würzburg
Chao Wang
Chao Wang Soochow University
Quanyin Hu
Quanyin Hu University of North Carolina at Chapel Hill
Oliver Kurzai
Oliver Kurzai University of Würzburg
Charles A. Gersbach
Charles A. Gersbach Duke University

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