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Genetics

D-Index
64
Citations
35557
World Ranking
2734
National Ranking
1201

Research.com Recognitions

  • 2017 - Fellow of Alfred P. Sloan Foundation

Overview

Lei S. Qi is a researcher affiliated with Stanford University in the United States. Their work primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions to Medicine as well. Within these broad areas, their subfields of expertise include Molecular Biology, Oncology, Genetics, Cardiology and Cardiovascular Medicine, and Infectious Diseases.

The main topics covered in Lei S. Qi's research encompass CRISPR and Genetic Engineering, RNA and protein synthesis mechanisms, CAR-T cell therapy research, Viral Infections and Immunology Research, RNA Interference and Gene Delivery, Single-cell and spatial transcriptomics, and Pluripotent Stem Cells Research.

Lei S. Qi has published extensively, with a notable number of papers appearing in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, The CRISPR Journal, Cell, and Molecular Cell. These platforms reflect the emphasis on molecular biology and CRISPR technologies in their work.

Frequently collaborating with other scientists, Lei S. Qi's frequent co-authors include Leiping Zeng, Mengting Han, Xueqiu Lin, Haifeng Wang, and Augustine Chemparathy.

Some of their recent scientific publications include:

  • High-content CRISPR screening (2022) published in Nature Reviews Methods Primers
  • Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza (2020) published in Cell
  • CRISPR technologies for precise epigenome editing (2021) published in Nature Cell Biology
  • Engineered miniature CRISPR-Cas system for mammalian genome regulation and editing (2021) published in Molecular Cell
  • Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells (2020) published in Nature Communications

Lei S. Qi has been recognized with the award Fellow of Alfred P. Sloan Foundation in 2017.

Best Publications

  • Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.

    Lei S. Qi;Matthew H. Larson;Luke A. Gilbert;Jennifer A. Doudna

  • CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

    Luke A. Gilbert;Matthew H. Larson;Leonardo Morsut;Zairan Liu

  • Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

    Luke A. Gilbert;Max A. Horlbeck;Britt Adamson;Jacqueline E. Villalta

  • Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System

    Baohui Chen;Luke A. Gilbert;Beth A. Cimini;Joerg Schnitzbauer

  • A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging

    Marvin E. Tanenbaum;Luke A. Gilbert;Lei S. Qi;Jonathan S. Weissman

  • CRISPR interference (CRISPRi) for sequence-specific control of gene expression

    Matthew H Larson;Luke A Gilbert;Luke A Gilbert;Xiaowo Wang;Wendell A Lim

  • CRISPR/Cas9 in Genome Editing and Beyond

    Haifeng Wang;Marie La Russa;Marie La Russa;Lei S. Qi

  • Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds

    Jesse G. Zalatan;Michael E. Lee;Ricardo Almeida;Luke A. Gilbert;Luke A. Gilbert

  • Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation

    Antonia A. Dominguez;Wendell A. Lim;Lei S. Qi

  • A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria

    Jason M. Peters;Alexandre Colavin;Handuo Shi;Tomasz L. Czarny

  • CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs

    Mohammad A. Mandegar;Nathaniel Huebsch;Ekaterina B. Frolov;Edward Shin

  • Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza.

    Timothy R. Abbott;Girija Dhamdhere;Yanxia Liu;Xueqiu Lin

  • Small Molecules Enhance CRISPR Genome Editing in Pluripotent Stem Cells

    Chen Yu;Yanxia Liu;Tianhua Ma;Kai Liu

  • Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions

    John Paul Shen;Dongxin Zhao;Roman Sasik;Jens Luebeck

  • CRISPR technologies for precise epigenome editing

    Muneaki Nakamura;Yuchen Gao;Antonia A Dominguez;Lei S Qi

  • Complex transcriptional modulation with orthogonal and inducible dCas9 regulators

    Yuchen Gao;Xin Xiong;Spencer Wong;Emeric J Charles

  • A CRISPR-dCas Toolbox for Genetic Engineering and Synthetic Biology.

    Xiaoshu Xu;Lei S. Qi

  • Versatile RNA-sensing transcriptional regulators for engineering genetic networks

    Julius B. Lucks;Lei Qi;Vivek K. Mutalik;Denise Wang

  • Engineered miniature CRISPR-Cas system for mammalian genome regulation and editing.

    Xiaoshu Xu;Augustine Chemparathy;Leiping Zeng;Hannah R. Kempton

  • The New State of the Art: Cas9 for Gene Activation and Repression.

    Marie F La Russa;Lei S Qi

Frequent Co-Authors

Wendell A. Lim
Wendell A. Lim University of California, San Francisco
Adam P. Arkin
Adam P. Arkin Lawrence Berkeley National Laboratory
Jennifer A. Doudna
Jennifer A. Doudna University of California, Berkeley
Martin Jinek
Martin Jinek University of Zurich
Luke A. Gilbert
Luke A. Gilbert University of California, San Francisco
Emmanuelle Charpentier
Emmanuelle Charpentier Max Planck Institute for Infection Biology
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Sheng Ding
Sheng Ding Tsinghua University
Michael C. Bassik
Michael C. Bassik Stanford University

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