World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
43879
World Ranking
12865
National Ranking
227

Overview

Martin Jinek is affiliated with the University of Zurich in Switzerland and specializes in the field of Biochemistry, Genetics, and Molecular Biology. Their research portfolio includes 188 publications with a predominant focus on Molecular Biology, represented in 169 papers, along with contributions to Genetics, Endocrinology, Ecology, and Immunology.

The scientist's work extensively covers several main topics including:

  • CRISPR and Genetic Engineering
  • RNA and protein synthesis mechanisms
  • Advanced biosensing and bioanalysis techniques
  • RNA modifications and cancer
  • RNA Research and Splicing
  • RNA regulation and disease
  • RNA Interference and Gene Delivery

Frequent publication venues for their work demonstrate a focus on high-impact and specialized journals and datasets, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • EMPIAR dataset
  • Biophysical Journal
  • Nature Communications
  • Cell

Notable recent papers authored or co-authored by Martin Jinek include:

  • "In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels," 2021, Nature Biotechnology
  • "Past, present, and future of CRISPR genome editing technologies," 2024, Cell
  • "Structural basis for Cas9 off-target activity," 2022, Cell
  • "R-loop formation and conformational activation mechanisms of Cas9," 2022, Nature
  • "Hakai is required for stabilization of core components of the m6A mRNA methylation machinery," 2021, Nature Communications

Their network of frequent collaborators includes several researchers who appear repeatedly in joint publications. These co-authors are:

  • Martin Pačesa
  • Luuk Loeff
  • Irma Querques
  • Christelle Chanez
  • Giulia Palermo

Best Publications

  • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

    Martin Jinek;Krzysztof Chylinski;Krzysztof Chylinski;Ines Fonfara;Michael Hauer

  • RNA-programmed genome editing in human cells

    Martin Jinek;Alexandra East;Aaron Cheng;Steven Lin

  • DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

    Samuel H. Sternberg;Sy Redding;Martin Jinek;Eric C. Greene

  • Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation

    Martin Jinek;Fuguo Jiang;David W. Taylor;David W. Taylor;Samuel H. Sternberg

  • Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

    Carolin Anders;Ole Niewoehner;Alessia Duerst;Martin Jinek

  • A three-dimensional view of the molecular machinery of RNA interference

    Martin Jinek;Jennifer A. Doudna

  • Sequence- and structure-specific RNA processing by a CRISPR endonuclease.

    Rachel E. Haurwitz;Martin Jinek;Blake Wiedenheft;Kaihong Zhou

  • A prudent path forward for genomic engineering and germline gene modification

    David Baltimore;Paul Berg;Michael Botchan;Dana Carroll

  • Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription

    Jennifer A. Doudna;Martin Jinek;Krzysztof Chylinski;Emmanuelle Charpentier

  • Structural biology of nucleocytoplasmic transport.

    Atlanta Cook;Fulvia Bono;Martin Jinek;Elena Conti

  • Structural insights into the molecular mechanism of the m(6)A writer complex.

    Paweł Śledź;Martin Jinek

  • Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

    Marc R. Fabian;Géraldine Mathonnet;Thomas Sundermeier;Hansruedi Mathys

  • Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.

    Daan C. Swarts;John van der Oost;Martin Jinek

  • Mechanistic Insights into the Cis- and Trans-acting Deoxyribonuclease Activities of Cas12a

    Daan C. Swarts;Martin Jinek

  • Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers.

    Ole Niewoehner;Carmela Garcia-Doval;Jakob T. Rostøl;Christian Berk

  • The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha.

    Martin Jínek;Jan Rehwinkel;Brooke D Lazarus;Elisa Izaurralde

  • Structural Basis for DNase Activity of a Conserved Protein Implicated in CRISPR-Mediated Genome Defense.

    Blake Wiedenheft;Kaihong Zhou;Martin Jinek;Scott M. Coyle

  • An RNA-Induced Conformational Change Required for Crispr RNA Cleavage by the Endoribonuclease Cse3.

    Dipali G Sashital;Martin Jinek;Jennifer A Doudna

  • Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes

    Alexa Burger;Helen Lindsay;Helen Lindsay;Anastasia Felker;Christopher Hess

  • In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels.

    Tanja Rothgangl;Melissa K Dennis;Paulo J C Lin;Rurika Oka

Frequent Co-Authors

Jennifer A. Doudna
Jennifer A. Doudna University of California, Berkeley
Lei S. Qi
Lei S. Qi Stanford University
Wendell A. Lim
Wendell A. Lim University of California, San Francisco
Emmanuelle Charpentier
Emmanuelle Charpentier Max Planck Institute for Infection Biology
Blake Wiedenheft
Blake Wiedenheft Montana State University
Mark D. Robinson
Mark D. Robinson University of Zurich
J. Andrew McCammon
J. Andrew McCammon University of California, San Diego
Luciano A. Marraffini
Luciano A. Marraffini Rockefeller University
Elena Conti
Elena Conti Max Planck Society

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