What is he best known for?
The fields of study he is best known for:
Virginijus Siksnys mostly deals with DNA, CRISPR, Cas9, RNA and Trans-activating crRNA.
His DNA study improves the overall literature in Biochemistry.
CRISPR is a subfield of Genetics that Virginijus Siksnys investigates.
In general Genetics, his work in Protospacer adjacent motif is often linked to R-loop and DNA supercoil linking many areas of study.
Sequence alignment and Ribonuclease III is closely connected to Cell biology in his research, which is encompassed under the umbrella topic of Cas9.
His RNA research integrates issues from Molecular biology and Effector.
His most cited work include:
- Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria (1659 citations)
- The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli (677 citations)
- Cas3 is a single‐stranded DNA nuclease and ATP‐dependent helicase in the CRISPR/Cas immune system (297 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are DNA, Restriction enzyme, Biochemistry, CRISPR and Genetics.
In his work, Nucleic acid sequence is strongly intertwined with Molecular biology, which is a subfield of DNA.
His work deals with themes such as Restriction fragment, Cleavage, Stereochemistry and Active site, which intersect with Restriction enzyme.
His CRISPR research includes themes of RNA, Computational biology and Cell biology.
His CRISPR interference study in the realm of Genetics connects with subjects such as DNA supercoil.
His studies deal with areas such as Genome editing and Acquired immune system as well as Cas9.
He most often published in these fields:
- DNA (58.70%)
- Restriction enzyme (49.28%)
- Biochemistry (34.06%)
What were the highlights of his more recent work (between 2018-2021)?
- CRISPR (30.43%)
- Computational biology (21.01%)
- Cas9 (23.19%)
In recent papers he was focusing on the following fields of study:
Virginijus Siksnys mainly focuses on CRISPR, Computational biology, Cas9, Genome editing and RNA.
His CRISPR research is multidisciplinary, relying on both Cell biology, Effector, Protein subunit and Endonuclease.
His biological study spans a wide range of topics, including Genome, DNA, Base pair, Gene and Nuclease.
His DNA research incorporates themes from Nucleotide, Dimer, Stereochemistry, Protein structure and Binding site.
His studies in Cas9 integrate themes in fields like Bacteriophage and DNA-binding protein.
He has included themes like Trans-activating crRNA and Cleavage in his RNA study.
Between 2018 and 2021, his most popular works were:
- Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants. (282 citations)
- CRISPR-Cas9 Editing in Maize: Systematic Evaluation of Off-target Activity and Its Relevance in Crop Improvement. (22 citations)
- PAM recognition by miniature CRISPR-Cas12f nucleases triggers programmable double-stranded DNA target cleavage. (19 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include CRISPR, Computational biology, Cas9, DNA and RNA.
His research in CRISPR focuses on subjects like Cleave, which are connected to Plasmid.
His study ties his expertise on Binding site together with the subject of Cas9.
His DNA study incorporates themes from Bacteriophage, DNA-binding protein, Dimer, Stereochemistry and Protein structure.
Many of his studies on RNA apply to Cell biology as well.
Virginijus Siksnys has researched Guide RNA in several fields, including Nuclease, Genome engineering, Genetic variation and Homology.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
