World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
99
Citations
66349
World Ranking
767
National Ranking
381

Molecular Biology

D-Index
99
Citations
66349
World Ranking
542
National Ranking
298

Research.com Recognitions

  • 2010 - National Institutes of Health Director's Pioneer Award

Overview

J. Keith Joung is affiliated with Harvard University in the United States and focuses on research within biochemistry, genetics, and molecular biology. Their work primarily concentrates on molecular biology, genetics, and plant science, while also spanning oncology and business and international management in smaller capacities.

The scientist's research covers key topics including CRISPR and genetic engineering, RNA and protein synthesis mechanisms, RNA regulation and disease, advanced biosensing and bioanalysis techniques, virus-based gene therapy research, innovation and socioeconomic development, and mosquito-borne diseases and control.

Joung has contributed frequently to several scientific venues. These include bioRxiv (Cold Spring Harbor Laboratory), Nature Biotechnology, Nature Communications, Nature Protocols, and Molecular Therapy - Nucleic Acids.

Among their recent papers are the following:

  • CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells, 2020, Nature Biotechnology
  • Therapeutic base editing of human hematopoietic stem cells, 2020, Nature Medicine
  • A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing, 2020, Nature Biotechnology
  • Optimization of AsCas12a for combinatorial genetic screens in human cells, 2020, Nature Biotechnology
  • CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells, 2021, Nature Biotechnology

They have collaborated extensively with notable coauthors, including Luca Pinello, Karl Petri, Jonathan Y. Hsu, Kendell Clement, and Martin J. Aryee, among others.

Best Publications

  • CRISPR-Cas systems for editing, regulating and targeting genomes

    Jeffry D Sander;J Keith Joung

  • High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.

    Yanfang Fu;Jennifer A Foden;Cyd Khayter;Morgan L Maeder

  • Efficient genome editing in zebrafish using a CRISPR-Cas system

    Woong Y. Hwang;Yanfang Fu;Deepak Reyon;Morgan L. Maeder

  • High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects

    Benjamin P. Kleinstiver;Vikram Pattanayak;Michelle S. Prew;Shengdar Q. Tsai

  • Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

    Yanfang Fu;Jeffry D Sander;Deepak Reyon;Vincent M Cascio

  • GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

    Shengdar Q Tsai;Zongli Zheng;Nhu T Nguyen;Matthew Liebers

  • TALENs: a widely applicable technology for targeted genome editing

    J. Keith Joung;Jeffry D. Sander

  • Engineered CRISPR-CAS9 nucleases with altered PAM specificity

    J. Keith Joung;Benjamin Kleinstiver

  • Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

    John A. Zuris;David B. Thompson;Yilai Shu;John Paul Guilinger

  • FLASH assembly of TALENs for high-throughput genome editing

    Deepak Reyon;Shengdar Q Tsai;Cyd Khayter;Jennifer A Foden

  • CRISPR RNA–guided activation of endogenous human genes

    Morgan L Maeder;Samantha J Linder;Vincent M Cascio;Yanfang Fu

  • Gene therapy comes of age.

    Cynthia E. Dunbar;Katherine A. High;J. Keith Joung;Donald B. Kohn

  • CRISPResso2 provides accurate and rapid genome editing sequence analysis.

    Clement K;Rees H;Canver Mc;Canver Mc;Gehrke Jm

  • Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

    Shengdar Q Tsai;Nicolas Wyvekens;Cyd Khayter;Jennifer A Foden

  • Enhanced Proofreading Governs CRISPR-Cas9 Targeting Accuracy

    Janice S. Chen;Yavuz S. Dagdas;Benjamin P. Kleinstiver;Moira M. Welch

  • Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification.

    Morgan L. Maeder;Stacey Thibodeau-Beganny;Anna Osiak;David A. Wright

  • High-frequency modification of plant genes using engineered zinc-finger nucleases

    Jeffrey A. Townsend;David A. Wright;Ronnie J. Winfrey;Fengli Fu

  • Targeted gene disruption in somatic zebrafish cells using engineered TALENs.

    Jeffry D Sander;Lindsay Cade;Cyd Khayter;Deepak Reyon

  • Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)

    Jeffry D. Sander;Elizabeth J. Dahlborg;Mathew J. Goodwin;Lindsay Cade

  • 731. High-Fidelity CRISPR-Cas9 Nucleases with No Detectable Genome-Wide Off-Target Effects

    Benjamin P. Kleinstiver;Vikram Pattanayak;Michelle S. Prew;Shengdar Q. Tsai

Frequent Co-Authors

Shengdar Q. Tsai
Shengdar Q. Tsai St. Jude Children's Research Hospital
Daniel F. Voytas
Daniel F. Voytas University of Minnesota
Martin J. Aryee
Martin J. Aryee Harvard University
David R. Liu
David R. Liu Broad Institute
Randall T. Peterson
Randall T. Peterson University of Utah
Toni Cathomen
Toni Cathomen University of Freiburg
Matthew H. Porteus
Matthew H. Porteus Stanford University
Alexander F. Schier
Alexander F. Schier University of Basel
Daniel E. Bauer
Daniel E. Bauer Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring genetics opens the door to diverse career trajectories, many of which can be accessed through flexible online education. For students interested in blending genetics with health information management, pursuing a medical coding and billing certification is a valuable option. This qualification connects genetic data management to the growing demand in healthcare administration.

If advancing your studies quickly is a priority, consider looking into accelerated degree programs. These programs are designed to help motivated students earn degrees faster, allowing them to enter the workforce or pursue further specialization sooner.

For those who need maximum flexibility, the best accredited self-paced online colleges offer genetics and related courses that fit around work or personal responsibilities. These programs let you control your learning schedule and pace.

Finally, saving on application costs can make a significant difference. Explore universities with no application fee to apply to multiple programs without financial barriers.

Best Scientists Citing J. Keith Joung

Trending Scientists