What is he best known for?
The fields of study he is best known for:
Matthew H. Porteus spends much of his time researching Gene targeting, Genetics, Genome editing, Zinc finger and Zinc finger nuclease.
The various areas that he examines in his Gene targeting study include Mutation, Molecular biology, Stem cell and Chromatin.
His Genetics research is multidisciplinary, incorporating perspectives in Computational biology and Cell biology.
His Genome editing research incorporates themes from Ribonucleoprotein and Cas9.
His Zinc finger research includes elements of Transcription activator-like effector nuclease and Genome engineering.
His work in the fields of Homologous recombination, Complementary DNA, Molecular cloning and DLX6 overlaps with other areas such as Melanogaster.
His most cited work include:
- Highly efficient endogenous human gene correction using designed zinc-finger nucleases (1526 citations)
- Chimeric Nucleases Stimulate Gene Targeting in Human Cells (684 citations)
- Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. (639 citations)
What are the main themes of his work throughout his whole career to date?
Matthew H. Porteus mostly deals with Genome editing, Genetics, Stem cell, Haematopoiesis and Cell biology.
Matthew H. Porteus has researched Genome editing in several fields, including Computational biology and Homologous recombination.
His work on Genetics deals in particular with Gene, Zinc finger nuclease, Genome engineering, Locus and Transcription factor.
His research integrates issues of Molecular biology, Cancer research, Genetic enhancement and Transplantation in his study of Stem cell.
In his study, Bone marrow is strongly linked to Progenitor cell, which falls under the umbrella field of Haematopoiesis.
His study looks at the relationship between Gene targeting and fields such as Zinc finger, as well as how they intersect with chemical problems.
He most often published in these fields:
- Genome editing (36.12%)
- Genetics (28.63%)
- Stem cell (27.31%)
What were the highlights of his more recent work (between 2019-2021)?
- Stem cell (27.31%)
- Haematopoiesis (20.70%)
- Cell biology (21.59%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Stem cell, Haematopoiesis, Cell biology, Cancer research and Gene.
His biological study spans a wide range of topics, including Cystic fibrosis and CD19.
His Haematopoiesis study combines topics in areas such as Progenitor cell and Glucocerebrosidase.
His Cell biology study incorporates themes from Genome editing and Phenotype.
His studies in Genome editing integrate themes in fields like Cell and Disease.
His Gene study frequently draws connections between related disciplines such as Molecular biology.
Between 2019 and 2021, his most popular works were:
- High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia. (35 citations)
- Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells. (15 citations)
- Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards (14 citations)
In his most recent research, the most cited papers focused on:
Matthew H. Porteus focuses on Stem cell, Cell biology, Cancer research, Induced pluripotent stem cell and Transplantation.
The study incorporates disciplines such as Inflammation, T cell and Cytokine in addition to Stem cell.
Matthew H. Porteus combines subjects such as Phenotype, Premovement neuronal activity and Cellular model with his study of Cell biology.
The concepts of his Cancer research study are interwoven with issues in Haematopoiesis, HEK 293 cells, Genetic enhancement, Monocyte and Chimeric antigen receptor.
His Transplantation research includes themes of Genome editing, Cell and Bioinformatics.
His Genome editing study is concerned with the field of Genome as a whole.
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