What is he best known for?
The fields of study he is best known for:
Molecular biology, Cell biology, Genetics, Haematopoiesis and Cellular differentiation are his primary areas of study.
His studies in Molecular biology integrate themes in fields like Complementary DNA, Transcription factor, Gene expression, Gene and Erythroid-Specific DNA-Binding Factors.
His Transcription factor study incorporates themes from Promoter and Regulation of gene expression.
He works in the field of Cell biology, namely Stem cell.
His study in Haematopoiesis is interdisciplinary in nature, drawing from both Progenitor cell and Cancer research.
Stuart H. Orkin interconnects SOX2 and Homeobox protein NANOG in the investigation of issues within Cellular differentiation.
His most cited work include:
- Epigenetic memory in induced pluripotent stem cells (1761 citations)
- Hematopoiesis: an evolving paradigm for stem cell biology. (1723 citations)
- An early haematopoietic defect in mice lacking the transcription factor GATA-2. (1205 citations)
What are the main themes of his work throughout his whole career to date?
Stuart H. Orkin focuses on Molecular biology, Cell biology, Genetics, Gene and Transcription factor.
His Molecular biology research is multidisciplinary, incorporating perspectives in GATA1, Gene expression, Complementary DNA, Globin and Erythroid-Specific DNA-Binding Factors.
Stuart H. Orkin works mostly in the field of Cell biology, limiting it down to topics relating to Embryonic stem cell and, in certain cases, Reprogramming, as a part of the same area of interest.
His Gene research is mostly focused on the topic Transcription.
His Haematopoiesis research integrates issues from Progenitor cell, Cancer research, Bone marrow and Erythropoiesis.
His biological study spans a wide range of topics, including Enhancer and Epigenetics.
He most often published in these fields:
- Molecular biology (45.70%)
- Cell biology (45.80%)
- Genetics (37.51%)
What were the highlights of his more recent work (between 2012-2021)?
- Cell biology (45.80%)
- Genetics (37.51%)
- Regulation of gene expression (22.24%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cell biology, Genetics, Regulation of gene expression, Chromatin and Cancer research.
Stuart H. Orkin has researched Cell biology in several fields, including Embryonic stem cell, Transcription factor and Gene expression.
His Regulation of gene expression research incorporates elements of Translation and MYB.
His Chromatin research also works with subjects such as
- Enhancer that intertwine with fields like Computational biology, GATA1 and Locus,
- Histone which intersects with area such as Super-enhancer and Cohesin.
Stuart H. Orkin has included themes like Cell, Cellular differentiation and Immunology in his Stem cell study.
His research integrates issues of Molecular biology, Erythropoiesis, Bone marrow and Transplantation in his study of Haematopoiesis.
Between 2012 and 2021, his most popular works were:
- A comparative encyclopedia of DNA elements in the mouse genome (1022 citations)
- Mapping the Mouse Cell Atlas by Microwell-Seq (614 citations)
- BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis (546 citations)
In his most recent research, the most cited papers focused on:
Stuart H. Orkin mainly investigates Genetics, Regulation of gene expression, Chromatin, Cell biology and Stem cell.
His study ties his expertise on Transcription factor together with the subject of Regulation of gene expression.
His Chromatin research incorporates themes from Promoter, Chromatin immunoprecipitation, Gene expression and Epigenetics.
His research in Cell biology tackles topics such as Cellular differentiation which are related to areas like Molecular biology, Cell and Cell growth.
His work carried out in the field of Molecular biology brings together such families of science as Gene knockdown and Single-cell analysis.
His study in Stem cell focuses on Haematopoiesis and Progenitor cell.
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