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Molecular Biology

D-Index
96
Citations
36156
World Ranking
606
National Ranking
48

Research.com Recognitions

  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Berthold Göttgens is affiliated with the University of Cambridge in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a strong presence in Medicine. Key subfields include Molecular Biology, Hematology, Immunology, Genetics, and Cell Biology.

The scientist's work is concentrated on several main topics including Single-cell and spatial transcriptomics, Acute Myeloid Leukemia Research, Hematopoietic Stem Cell Transplantation, Immune cells in cancer, Zebrafish Biomedical Research Applications, Epigenetics and DNA Methylation, and Pluripotent Stem Cells Research.

Frequent co-authors in their publications consist of Nicola K. Wilson, Fernando J. Calero-Nieto, Sarah Kinston, Iwo Kuciński, and John C. Marioni.

Berthold Göttgens has published extensively in several scientific venues. The most common publication outlets include bioRxiv (Cold Spring Harbor Laboratory) with 49 publications, Experimental Hematology with 28, Blood with 21, Nature Cell Biology with 9, and Nature Communications with 8.

Their recent papers include the following:

  • Single-cell multi-omics analysis of the immune response in COVID-19, 2021, Nature Medicine
  • Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease, 2021, Immunity
  • Local and systemic responses to SARS-CoV-2 infection in children and adults, 2021, Nature
  • Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis, 2021, Nature Biotechnology
  • A roadmap for the Human Developmental Cell Atlas, 2021, Nature

The scientist has been recognized by being named a Fellow of The Academy of Medical Sciences, United Kingdom, and as a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • The Human Cell Atlas

    Aviv Regev;Aviv Regev;Aviv Regev;Sarah A Teichmann;Sarah A Teichmann;Sarah A Teichmann;Eric S Lander;Eric S Lander;Eric S Lander;Ido Amit

  • PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

    F. Alexander Wolf;Fiona K. Hamey;Mireya Plass;Jordi Solana

  • A single-cell molecular map of mouse gastrulation and early organogenesis.

    Blanca Pijuan-Sala;Jonathan A. Griffiths;Carolina Guibentif;Tom W. Hiscock

  • Combinatorial transcriptional control in blood stem/progenitor cells: Genome-wide analysis of ten major transcriptional regulators

    Nicola K. Wilson;Samuel D. Foster;Xiaonan Wang;Kathy Knezevic

  • From haematopoietic stem cells to complex differentiation landscapes

    Elisa Laurenti;Berthold Göttgens

  • JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin

    Mark A. Dawson;Andrew J. Bannister;Berthold Göttgens;Samuel D. Foster

  • A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation.

    Sonia Nestorowa;Fiona K. Hamey;Blanca Pijuan Sala;Evangelia Diamanti

  • Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions

    Eric M. Pietras;Damien Reynaud;Yoon-A. Kang;Daniel Carlin

  • Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal

    Deqiang Sun;Min Luo;Mira Jeong;Benjamin Rodriguez

  • Decoding human fetal liver haematopoiesis

    Dorin-Mirel Popescu;Rachel A. Botting;Emily Stephenson;Kile Green

  • Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes

    Alexander W. Bruce;Ian J. Donaldson;Ian C. Wood;Sally A. Yerbury

  • The SCL gene specifies haemangioblast development from early mesoderm

    M. Gering;A.R.F. Rodaway;B. Göttgens;R.K. Patient

  • Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

    Nicola K. Wilson;David G. Kent;Florian Buettner;Mona Shehata

  • Decoding the regulatory network of early blood development from single-cell gene expression measurements

    Victoria Moignard;Steven Woodhouse;Laleh Haghverdi;Andrew J Lilly

  • Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal.

    Graziano Martello;Toshimi Sugimoto;Evangelia Diamanti;Anagha Joshi

  • Multi-omics profiling of mouse gastrulation at single-cell resolution.

    Ricard Argelaguet;Stephen J. Clark;Hisham Mohammed;L. Carine Stapel

  • Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium.

    Joachim R. Göthert;Sonja E. Gustin;J. Anke M. van Eekelen;Uli Schmidt

  • Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif.

    Diogo S. Castro;Dorota Skowronska-Krawczyk;Dorota Skowronska-Krawczyk;Olivier Armant;Olivier Armant;Ian J. Donaldson

  • Large conserved domains of low DNA methylation maintained by Dnmt3a.

    Mira Jeong;Deqiang Sun;Min Luo;Yun Huang

  • Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis

    Victoria Moignard;Iain C. Macaulay;Gemma Swiers;Florian Buettner

Frequent Co-Authors

Anthony R. Green
Anthony R. Green University of Cambridge
John C. Marioni
John C. Marioni European Bioinformatics Institute
Sarah A. Teichmann
Sarah A. Teichmann University of Cambridge
Valerie Kouskoff
Valerie Kouskoff University of Manchester
María José Sánchez
María José Sánchez University of Granada
Wolf Reik
Wolf Reik Babraham Institute
Benjamin D. Simons
Benjamin D. Simons University of Cambridge
Georges Lacaud
Georges Lacaud University of Manchester
Willem H. Ouwehand
Willem H. Ouwehand University of Cambridge
Muzlifah Haniffa
Muzlifah Haniffa Newcastle University

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