What is she best known for?
The fields of study she is best known for:
Constanze Bonifer mainly focuses on Molecular biology, Chromatin, Transcription factor, Gene expression and Genetics.
Her Molecular biology research is multidisciplinary, incorporating elements of Enhancer, Chromatin remodeling, Transcription, Adenomatous polyposis coli and Familial adenomatous polyposis.
Her Chromatin research incorporates themes from Epigenetics, Cellular differentiation, Regulatory sequence and Ectopic expression.
Her Cell biology research extends to Transcription factor, which is thematically connected.
Locus is closely connected to Transgene in her research, which is encompassed under the umbrella topic of Gene expression.
Her research investigates the connection with Genetics and areas like Computational biology which intersect with concerns in Gene regulatory network, Gene silencing, Sequence analysis, Deoxyribonuclease I and Genome.
Her most cited work include:
- Tissue specific and position independent expression of the complete gene domain for chicken lysozyme in transgenic mice. (249 citations)
- Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma (229 citations)
- Localization of cyclooxygenase-2 in human sporadic colorectal adenomas. (204 citations)
What are the main themes of her work throughout her whole career to date?
Constanze Bonifer mostly deals with Transcription factor, Chromatin, Cell biology, Molecular biology and Genetics.
The various areas that Constanze Bonifer examines in her Transcription factor study include Regulation of gene expression, Cellular differentiation and Gene regulatory network.
Her Chromatin research integrates issues from Gene expression and Epigenetics.
The Cell biology study combines topics in areas such as Embryonic stem cell and Reprogramming.
Her Molecular biology study integrates concerns from other disciplines, such as Lysozyme, Enhancer, Promoter, DNase I hypersensitive site and Binding site.
Her study ties her expertise on Computational biology together with the subject of Genetics.
She most often published in these fields:
- Transcription factor (51.21%)
- Chromatin (47.83%)
- Cell biology (35.27%)
What were the highlights of her more recent work (between 2017-2021)?
- Cell biology (35.27%)
- Transcription factor (51.21%)
- RUNX1 (23.19%)
In recent papers she was focusing on the following fields of study:
Constanze Bonifer spends much of her time researching Cell biology, Transcription factor, RUNX1, Myeloid leukemia and Chromatin.
Her research integrates issues of Embryonic stem cell, Gene expression and Epigenetics in her study of Cell biology.
Her Transcription factor research incorporates themes from Regulation of gene expression and Gene regulatory network.
Her study in RUNX1 is interdisciplinary in nature, drawing from both Myeloid and Regulator.
Her Myeloid leukemia research integrates issues from Leukemia, Gene, Somatic evolution in cancer and DNA.
Her Chromatin research incorporates elements of Mutation and Cell fate determination.
Between 2017 and 2021, her most popular works were:
- Subtype-specific regulatory network rewiring in acute myeloid leukemia (62 citations)
- The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation. (37 citations)
- Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones (32 citations)
In her most recent research, the most cited papers focused on:
Transcription factor, RUNX1, Myeloid leukemia, Cell biology and Regulation of gene expression are her primary areas of study.
Her Transcription factor study often links to related topics such as Chromatin.
Her biological study spans a wide range of topics, including Transcription factor complex, Haematopoiesis, Progenitor cell, FLI1 and General transcription factor.
Her work deals with themes such as Myeloid and Leukemia, which intersect with RUNX1.
Much of her study explores Cell biology relationship to Gene expression.
Her study looks at the intersection of Regulation of gene expression and topics like Epigenetics with Cell signaling, Transcriptional regulation, Epigenomics and Computational biology.
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