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D-Index & Metrics

Molecular Biology

D-Index
61
Citations
15611
World Ranking
1895
National Ranking
133

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Achim Leutz is affiliated with the Max Delbrück Center for Molecular Medicine in Germany. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology.

The scientist has contributed extensively to subfields such as Molecular Biology, Immunology, Oncology, Pulmonary and Respiratory Medicine, and Surgery. Their work focuses on several key topics including Epigenetics and DNA Methylation, Immunotherapy and Immune Responses, Cancer-related gene regulation, Immune responses and vaccinations, Immune cells in cancer, Protein Degradation and Inhibitors, and RNA and protein synthesis mechanisms.

Achim Leutz has published in various scientific venues with frequent appearances in bioRxiv (Cold Spring Harbor Laboratory), Cell Stem Cell, Nature Immunology, iScience, and eLife.

  • Recent papers:
  • C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells, 2020, Cell Stem Cell
  • Cxcl10+ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation, 2020, Nature Immunology
  • C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells, 2020, Cell Stem Cell
  • C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages, 2022, Science Immunology
  • CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis, 2022, Annals of the Rheumatic Diseases

Frequent collaborators in research include Alexander Mildner, Dorothea Dörr, Karin Zimmermann, Elisabeth Kowenz-Leutz, and Ido Amit.

Best Publications

  • The c-erb-A protein is a high-affinity receptor for thyroid hormone

    Jan Sap;Alberto Muñoz;Klaus Damm;Yves Goldberg

  • Translational control of C/EBPalpha and C/EBPbeta isoform expression.

    Cor F. Calkhoven;Christine Müller;Achim Leutz

  • DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction

    Ann-Marie Bröske;Lena Vockentanz;Shabnam Kharazi;Matthew R Huska

  • Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation

    Marina Scheller;Joerg Huelsken;Frank Rosenbauer;Makoto Mark Taketo

  • A C/EBPβ Isoform Recruits the SWI/SNF Complex to Activate Myeloid Genes

    Elisabeth Kowenz-Leutz;Achim Leutz

  • Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein

    Philippe Dhordain;Olivier Albagli;Richard J. Lin;Stéphane Ansieau

  • The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators.

    R Dechend;F Hirano;K Lehmann;V Heissmeyer

  • Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell types.

    Scott A. Ness;Elisabeth Kowenz-Leutz;Tullia Casini;Thomas Graf

  • A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

    Henri Marc Bourbon;Andres Aguilera;Aseem Z. Ansari;Francisco J. Asturias

  • Chlamydia pneumoniae infection of vascular smooth muscle and endothelial cells activates NF-kappaB and induces tissue factor and PAI-1 expression: a potential link to accelerated arteriosclerosis.

    Ralf Dechend;M. Maass;J. Gieffers;R. Dietz

  • Cloning of two novel human importin-α subunits and analysis of the expression pattern of the importin-α protein family

    Matthias Köhler;Stéphane Ansieau;Siegfried Prehn;Achim Leutz

  • Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1

    Frank Rosenbauer;Frank Rosenbauer;Bronwyn M. Owens;Li Yu;Joseph R. Tumang

  • Novel mechanism of C/EBP beta (NF-M) transcriptional control: activation through derepression.

    Elisabeth Kowenz-Leutz;Geraldine Twamley;Stephane Ansieau;Achim Leutz

  • Genomic characterization of murine monocytes reveals C/EBPβ transcription factor dependence of Ly6C(-) cells

    Alexander Mildner;Alexander Mildner;Jörg Schönheit;Amir Giladi;Eyal David

  • Epidermal growth factor stimulates DNA-synthesis of astrocytes in primary cerebellar cultures

    A. Leutz;M. Schachner

  • Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin

    Grégoire Jeannet;Marina Scheller;Léonardo Scarpellino;Stéphane Duboux

  • C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells

    Bérengère de Laval;Julien Maurizio;Prashanth K. Kandalla;Prashanth K. Kandalla;Gabriel Brisou

  • Constitutive apical secretion of an 80-kD sulfated glycoprotein complex in the polarized epithelial Madin-Darby canine kidney cell line.

    Joachim Urban;Karsten Parczyk;Achim Leutz;Marlene Kayne

  • Upstream open reading frames: Molecular switches in (patho)physiology

    Klaus Wethmar;Jeske J. Smink;Achim Leutz

  • Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth

    David G. Simmons;David R. C. Natale;Valerie Begay;Martha Hughes

Frequent Co-Authors

Thomas Graf
Thomas Graf Centre for Genomic Regulation
Gunnar Dittmar
Gunnar Dittmar Luxembourg Institute of Health
Miguel A. Andrade-Navarro
Miguel A. Andrade-Navarro Johannes Gutenberg University of Mainz
Hartmut Beug
Hartmut Beug Research Institute of Molecular Pathology
Bernd Dörken
Bernd Dörken Charité - University Medicine Berlin
Walter Birchmeier
Walter Birchmeier Max Delbrück Center for Molecular Medicine
Ido Amit
Ido Amit Weizmann Institute of Science
Steffen Jung
Steffen Jung Weizmann Institute of Science
Udo Heinemann
Udo Heinemann Max Delbrück Center for Molecular Medicine

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