Marten P. Smidt mainly focuses on Dopaminergic, Neuroscience, Transcription factor, Dopamine and Cell biology. His work in the fields of Neuroscience, such as Tyrosine hydroxylase, Dopaminergic neuron and Axonal Pathfinding, intersects with other areas such as Insulin receptor. His research in Transcription factor focuses on subjects like Molecular biology, which are connected to Chromosomal translocation, Histone H3 and Cell culture.
The concepts of his Dopamine study are interwoven with issues in Homeobox and Midbrain. His work in Homeobox covers topics such as Embryonic stem cell which are related to areas like Retinoic acid. His study in Cell biology is interdisciplinary in nature, drawing from both CREB-binding protein, Acetylation, Transcriptional regulation and Cellular differentiation.
Marten P. Smidt mostly deals with Neuroscience, Dopaminergic, Transcription factor, Dopamine and Cell biology. He works mostly in the field of Dopaminergic, limiting it down to topics relating to Embryonic stem cell and, in certain cases, Retinoic acid. His study in Homeobox and Forkhead Transcription Factors is carried out as part of his studies in Transcription factor.
His Dopamine research focuses on Tyrosine hydroxylase in particular. His research integrates issues of Chromatin, Regulation of gene expression, Epigenetics and Histone deacetylase 2 in his study of Cell biology. The various areas that Marten P. Smidt examines in his Midbrain study include Hindbrain and Anatomy.
The scientist’s investigation covers issues in Neuroscience, Dopaminergic, Dopamine, Midbrain and Substantia nigra. Marten P. Smidt is interested in Ventral tegmental area, which is a field of Neuroscience. Marten P. Smidt has researched Dopaminergic in several fields, including Progenitor cell, Transcription factor, Serotonergic, Cell biology and Neuronal differentiation.
His Dopamine study combines topics from a wide range of disciplines, such as Genetically modified mouse, Transgene, Glutamate receptor, 5-HT receptor and Biological neural network. Marten P. Smidt combines subjects such as Dopaminergic Cell and Anatomy with his study of Midbrain. His studies deal with areas such as Floor plate, ASCL1 and Neuron as well as Substantia nigra.
His primary scientific interests are in Neuroscience, Gene knockdown, Substantia nigra, Dopaminergic and Transcription factor. His Neuroscience research focuses on Parkinson's disease and how it connects with Neurodegeneration, Brainstem and Developmental biology. His Substantia nigra research is multidisciplinary, incorporating elements of Ventral tegmental area and ASCL1.
His work deals with themes such as Homeobox, Dopaminergic Cell and Hindbrain, which intersect with Ventral tegmental area. His Dopaminergic study is associated with Dopamine. His Transcription factor study incorporates themes from Gliogenesis, Axon guidance, Plexin, Neocortex and Transcriptome.
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Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons.
Odila Saucedo-Cardenas;Juan D. Quintana-Hau;Wei-Dong Le;Marten P. Smidt.
Proceedings of the National Academy of Sciences of the United States of America (1998)
The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation.
Lars P Van Der Heide;Marco F M Hoekman;Marten P Smidt.
Biochemical Journal (2004)
A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b.
Marten P. Smidt;Ceriel H. J. Asbreuk;Joke J. Cox;Haixu Chen.
Nature Neuroscience (2000)
Insulin signaling in the central nervous system: learning to survive.
Lars P. van der Heide;Geert M.J. Ramakers;Marten P. Smidt.
Progress in Neurobiology (2006)
A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons
Marten P. Smidt;Hermien S. A. van Schaick;Christian Lanctôt;Jacques J. Tremblay.
Proceedings of the National Academy of Sciences of the United States of America (1997)
FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics.
Frank M.J. Jacobs;Lars P. van der Heide;Patrick J.E.C. Wijchers;J.Peter H. Burbach.
Journal of Biological Chemistry (2003)
How to make a mesodiencephalic dopaminergic neuron
Marten P. Smidt;J. Peter H. Burbach.
Nature Reviews Neuroscience (2007)
U-SPECT-I: A Novel System for Submillimeter-Resolution Tomography with Radiolabeled Molecules in Mice
Freek J Beekman;Frans van der Have;Brendan Vastenhouw;Annemarie J A van der Linden.
The Journal of Nuclear Medicine (2005)
Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3.
Marten P. Smidt;Simone M. Smits;Hans Bouwmeester;Frank P. T. Hamers.
Development (2004)
Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons.
Simone M. Smits;Tiia Ponnio;Orla M. Conneely;J. Peter H. Burbach.
European Journal of Neuroscience (2003)
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