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Neuroscience

D-Index
49
Citations
11244
World Ranking
5906
National Ranking
167

Overview

Marten P. Smidt is affiliated with the University of Amsterdam in the Netherlands. Their research mainly centers around biochemistry, genetics, molecular biology, and neuroscience, with a strong focus on molecular biology and cellular and molecular neuroscience.

The scientist has contributed to several key topics in their field, including:

  • Genetics and neurodevelopmental disorders
  • Nuclear receptors and signaling
  • Congenital heart defects research
  • Receptor mechanisms and signaling
  • Epigenetics and DNA methylation
  • Circadian rhythm and melatonin
  • Neuroscience and neuropharmacology research

Marten P. Smidt's publication record includes papers in highly regarded journals, such as The Lancet Psychiatry, Molecular and Cellular Neuroscience, Neuron, International Journal of Molecular Sciences, and Genome Research. Some of the recent papers are:

  • Advancing urban mental health research: from complexity science to actionable targets for intervention (2021, The Lancet Psychiatry)
  • Tcf4 is required for correct brain development during embryogenesis (2020, Molecular and Cellular Neuroscience)
  • The continued need for animals to advance brain research (2021, Neuron)
  • Acquisition of the Midbrain Dopaminergic Neuronal Identity (2020, International Journal of Molecular Sciences)
  • ZNF91 deletion in human embryonic stem cells leads to ectopic activation of SVA retrotransposons and up-regulation of KRAB zinc finger gene clusters (2021, Genome Research)

Their collaborative network features several frequent coauthors with whom they have multiple joint publications, including Lars P. van der Heide, Lars von Oerthel, Simone Mesman, Willemieke M. Kouwenhoven, and Erik H. Douma.

Publication venues where Marten P. Smidt has frequently contributed include:

  • International Journal of Molecular Sciences
  • Cell Death and Disease
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Lancet Psychiatry
  • Molecular and Cellular Neuroscience

Their research spans various subfields with particular emphasis on molecular biology, cellular and molecular neuroscience, and genetics. This focus supports an interdisciplinary approach linking molecular mechanisms to broader physiological and developmental phenomena.

Best Publications

  • Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons.

    Odila Saucedo-Cardenas;Juan D. Quintana-Hau;Wei-Dong Le;Marten P. Smidt

  • Insulin signaling in the central nervous system: learning to survive.

    Lars P. van der Heide;Geert M.J. Ramakers;Marten P. Smidt

  • A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b.

    Marten P. Smidt;Ceriel H. J. Asbreuk;Joke J. Cox;Haixu Chen

  • FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics.

    Frank M.J. Jacobs;Lars P. van der Heide;Patrick J.E.C. Wijchers;J.Peter H. Burbach

  • A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons

    Marten P. Smidt;Hermien S. A. van Schaick;Christian Lanctôt;Jacques J. Tremblay

  • How to make a mesodiencephalic dopaminergic neuron

    Marten P. Smidt;J. Peter H. Burbach

  • Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3.

    Marten P. Smidt;Simone M. Smits;Hans Bouwmeester;Frank P. T. Hamers

  • Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system.

    Edgar R Kramer;Liviu Aron;Geert M. J Ramakers;Sabine Seitz

  • Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons.

    Simone M. Smits;Tiia Ponnio;Orla M. Conneely;J. Peter H. Burbach

  • Disruption of the gene Euchromatin Histone Methyl Transferase1 (Eu-HMTase1) is associated with the 9q34 subtelomeric deletion syndrome

    T. Kleefstra;M. Smidt;M.J.G. Banning;A.R. Oudakker

  • Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain

    Marco F.M. Hoekman;Frank M.J. Jacobs;Marten P. Smidt;J. Peter H. Burbach

  • Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression.

    Frank M. J. Jacobs;Susan van Erp;Annemarie J. A. van der Linden;Lars von Oerthel

  • Modulation of serotonin transporter function during fetal development causes dilated heart cardiomyopathy and lifelong behavioral abnormalities.

    Cornelle W. Noorlander;Frederique F. T. Ververs;Peter G. J. Nikkels;Cees J. A. van Echteld

  • Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice.

    Paola Sgadò;Lavinia Albéri;Daniel Gherbassi;Sherri L. Galasso

  • Evolution of arthropod hemocyanins and insect storage proteins (hexamerins).

    Jaap J. Beintema;Wytze T. Stam;Bart Hazes;Marten P. Smidt

  • Developmental origin and fate of meso-diencephalic dopamine neurons.

    Simone M. Smits;J. Peter H. Burbach;Marten P. Smidt

  • Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency

    Frank M. J. Jacobs;Simone M. Smits;Cornelle W. Noorlander;Lars von Oerthel

  • Homeobox Gene Pitx3 and Its Role in the Development of Dopamine Neurons of the Substantia Nigra

    Marten P. Smidt;Simone M. Smits;J. Peter H. Burbach

  • A response element for the homeodomain transcription factor Ptx3 in the tyrosine hydroxylase gene promoter.

    P. Cazorla;M. P. Smidt;K. L. O'malley;J. P. H. Burbach

  • Semaphorin 3F Is a Bifunctional Guidance Cue for Dopaminergic Axons and Controls Their Fasciculation, Channeling, Rostral Growth, and Intracortical Targeting

    Sharon M. Kolk;Rou Afza F. Gunput;Tracy S. Tran;Dianne M.A. Van Den Heuvel

Frequent Co-Authors

Geert M.J. Ramakers
Geert M.J. Ramakers Utrecht University
Frank C. P. Holstege
Frank C. P. Holstege Utrecht University
Roger A.H. Adan
Roger A.H. Adan Utrecht University
Ralph E. Mistlberger
Ralph E. Mistlberger Simon Fraser University
Richard H. Dyck
Richard H. Dyck University of Calgary
Rüdiger Klein
Rüdiger Klein Max Planck Society
Martien J H Kas
Martien J H Kas University of Groningen
Jochen Graw
Jochen Graw Technical University of Munich
Martin Hrabé de Angelis
Martin Hrabé de Angelis Technical University of Munich
Erik A. Sistermans
Erik A. Sistermans University of Amsterdam

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