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Genetics

D-Index
64
Citations
14821
World Ranking
2792
National Ranking
352

Overview

Dario Acampora is affiliated with King's College London in the United Kingdom. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with a significant contribution to Medicine. Within these areas, they have specialized in subfields including Molecular Biology, Genetics, Pediatrics, Perinatology and Child Health, and Surgery.

Their work addresses key topics such as Genetic Syndromes and Imprinting, Epigenetics and DNA Methylation, Prenatal Screening and Diagnostics, Pluripotent Stem Cells Research, Renal and related cancers, and Tissue Engineering and Regenerative Medicine.

Recent publications by Dario Acampora include:

  • A maternal-effect Padi6 variant causes nuclear and cytoplasmic abnormalities in oocytes, as well as failure of epigenetic reprogramming and zygotic genome activation in embryos (2024, Genes & Development)
  • Direct repression of Nanog and Oct4 by OTX2 modulates the contribution of epiblast-derived cells to germline and somatic lineage (2021, Development)
  • A maternal-effect Padi6 variant results in abnormal nuclear localization of DNMT1 and failure of epigenetic reprogramming and zygotic genome activation in mouse embryos (2023, bioRxiv (Cold Spring Harbor Laboratory))

Publications by Acampora have appeared in venues including Genes & Development, Development, and bioRxiv (Cold Spring Harbor Laboratory).

Collaborations form an important part of Acampora's research activity. Frequent co-authors include Carlo Giaccari, Francesco Cecere, Lucia Argenziano, António Galvão, and Gianna Rossi, each having contributed to multiple works with Acampora.

Best Publications

  • Nested expression domains of four homeobox genes in developing rostral brain.

    Antonio Simeone;Dario Acampora;Massimo Gulisano;Anna Stornaiuolo

  • Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation

    Dario Acampora;Sylvie Mazan;Yvan Lallemand;Virginia Avantaggiato

  • A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo.

    Antonio Simeone;Dario Acampora;Antonio Mallamaci;Anna Stornaiuolo

  • Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

    Antonio Simeone;Dario Acampora;Laura Arcioni;Peter W. Andrews

  • Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5

    Dario Acampora;Giorgio R. Merlo;Laura Paleari;Barbara Zerega

  • Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex.

    Antonio Simeone;Massimo Gulisano;Dario Acampora;Anna Stornaiuolo

  • Reorganization of Enhancer Patterns in Transition from Naive to Primed Pluripotency

    Christa Buecker;Rajini Srinivasan;Zhixiang Wu;Eliezer Calo

  • The human HOX gene family

    Dario Acampora;Maurizio D'Esposito;Antonio Faiella;Maria Pannese

  • Cloning and characterization of two members of the vertebrate Dlx gene family.

    A Simeone;D Acampora;M Pannese;M D'Esposito

  • Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells

    Antonio Simeone;Dario Acampora;Vincenzo Nigro;Antonio Faiella

  • Otx genes are required for tissue specification in the developing eye

    Juan Ramon Martinez-Morales;Massimo Signore;Massimo Signore;Dario Acampora;Antonio Simeone

  • Identification of the Syrian Hamster Cardiomyopathy Gene

    Vincenzo Nigro;Yasushi Okazaki;Angela Belsito;Giulio Piluso

  • Epilepsy and brain abnormalities in mice lacking the Otx1 gene.

    Dario Acampora;Sylvie Mazan;Virginia Avantaggiato;Paolo Barone

  • HOX gene activation by retinoic acid

    Edoardo Boncinelli;Antonio Simeone;Dario Acampora;Fulvio Mavilio

  • Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain.

    Eduardo Puelles;Alessandro Annino;Francesca Tuorto;Alessandro Usiello

  • Genetic control of brain morphogenesis through Otx gene dosage requirement

    Dario Acampora;Virginia Avantaggiato;Francesca Tuorto;Antonio Simeone

  • Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene.

    Dario Acampora;Maria Pia Postiglione;Virginia Avantaggiato;Maria Di Bonito

  • Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition.

    Dario Acampora;Luca G. Di Giovannantonio;Antonio Simeone

  • Alternative splicing of PML transcripts predicts coexpression of several carboxy-terminally different protein isoforms.

    Fagioli M;Alcalay M;Pandolfi Pp;Venturini L

  • Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and drosophila

    Antonio Simeone;Maria Rosaria D'Apice;Vincenzo Nigro;Jordi Casanova

Frequent Co-Authors

Antonio Simeone
Antonio Simeone King's College London
Edoardo Boncinelli
Edoardo Boncinelli Vita-Salute San Raffaele University
Maurizio D'Esposito
Maurizio D'Esposito National Research Council (CNR)
Vincenzo Nigro
Vincenzo Nigro University of Campania "Luigi Vanvitelli"
Wolfgang Wurst
Wolfgang Wurst German Center for Neurodegenerative Diseases
Fulvio Mavilio
Fulvio Mavilio University of Modena and Reggio Emilia
Juan Pedro Martinez-Barbera
Juan Pedro Martinez-Barbera University College London
Giorgio Corte
Giorgio Corte University of Genoa
Heinrich Reichert
Heinrich Reichert University of Basel
Alain Prochiantz
Alain Prochiantz Collège de France

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