What is he best known for?
The fields of study he is best known for:
Timothy M. Lohman mainly investigates DNA, Biophysics, Biochemistry, Helicase and Nucleic acid.
The various areas that Timothy M. Lohman examines in his DNA study include Crystallography, Nucleotide, Single-stranded binding protein and Escherichia coli.
His Biophysics research incorporates themes from HMG-box, Molecular biology, Protein filament and Förster resonance energy transfer.
His research investigates the connection between Biochemistry and topics such as Stereochemistry that intersect with problems in Polynucleotide, Counterion, Counterion condensation and Binding constant.
His work is dedicated to discovering how Helicase, Binding site are connected with Enzyme and other disciplines.
His study on Nucleic acid also encompasses disciplines like
- Chromatography and related Titration, Membrane and Nitrocellulose,
- Ion which connect with Macromolecule.
His most cited work include:
- Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity. (1371 citations)
- Ion effects on ligand-nucleic acid interactions (864 citations)
- Mechanisms of helicase-catalyzed DNA unwinding. (643 citations)
What are the main themes of his work throughout his whole career to date?
DNA, Helicase, Biophysics, Biochemistry and Crystallography are his primary areas of study.
His DNA research integrates issues from Translocase, Nucleic acid, Single-stranded binding protein and Escherichia coli.
His Helicase research incorporates elements of RecBCD, ATP hydrolysis, Dimer, Circular bacterial chromosome and A-DNA.
His Biophysics research is multidisciplinary, incorporating perspectives in Replication protein A, Duplex, Molecular biology, Base pair and Förster resonance energy transfer.
His work on Binding site, Plasma protein binding, ATPase and Protein subunit as part of general Biochemistry research is frequently linked to DNA clamp, thereby connecting diverse disciplines of science.
His biological study spans a wide range of topics, including Equilibrium constant, Reaction rate constant, Isothermal titration calorimetry, Tetramer and Homotetramer.
He most often published in these fields:
- DNA (64.02%)
- Helicase (41.84%)
- Biophysics (41.84%)
What were the highlights of his more recent work (between 2016-2021)?
- Biophysics (41.84%)
- DNA (64.02%)
- Helicase (41.84%)
In recent papers he was focusing on the following fields of study:
Timothy M. Lohman spends much of his time researching Biophysics, DNA, Helicase, Escherichia coli and Single-stranded binding protein.
His research integrates issues of Replication protein A, Plasma protein binding, Protein subunit, Cooperative binding and Allosteric regulation in his study of Biophysics.
His studies deal with areas such as Nucleic acid, Tetramer and Cell biology as well as DNA.
His Helicase study combines topics in areas such as Processivity, Base pair and A-DNA.
Timothy M. Lohman interconnects Translocase and DNA repair in the investigation of issues within Escherichia coli.
The Single-stranded binding protein study combines topics in areas such as Prokaryotic DNA replication and dnaB helicase.
Between 2016 and 2021, his most popular works were:
- Dynamics of E. coli single stranded DNA binding (SSB) protein-DNA complexes (31 citations)
- Glutamate promotes SSB protein-protein Interactions via intrinsically disordered regions. (28 citations)
- Large domain movements upon UvrD dimerization and helicase activation. (20 citations)
In his most recent research, the most cited papers focused on:
Timothy M. Lohman focuses on Biophysics, DNA, Escherichia coli, Tetramer and DNA repair.
He combines subjects such as Photosynthetic reaction centre, Molecular mass, Single-stranded binding protein and Protein biosynthesis with his study of Biophysics.
His DNA study frequently draws connections to adjacent fields such as Plasma protein binding.
His work investigates the relationship between Tetramer and topics such as Cooperativity that intersect with problems in Cooperative binding, DNA replication and Gene.
DNA repair is closely attributed to Helicase in his research.
His study in Helicase is interdisciplinary in nature, drawing from both Dimer, Translocase and DNA mismatch repair.
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