M. Thomas Record

Research.com Recognitions

• 2007 - Fellow of the American Academy of Arts and Sciences
• 1991 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity.

  Record Mt;Anderson Cf;Lohman Tm

  2420
  Citations

• Ion effects on ligand-nucleic acid interactions

  M. Thomas Record;Timothy M. Lohman;Pieter de Haseth

  1239
  Citations

• Hofmeister salt effects on surface tension arise from partitioning of anions and cations between bulk water and the air-water interface.

  Laurel M. Pegram;M. Thomas Record

  548
  Citations

• Use of liquid hydrocarbon and amide transfer data to estimate contributions to thermodynamic functions of protein folding from the removal of nonpolar and polar surface from water.

  Unknown

  517
  Citations

• Responses of E. coli to osmotic stress: large changes in amounts of cytoplasmic solutes and water

  M.Thomas Record;Elizabeth S. Courtenay;D.Scott Cayley;Harry J. Guttman

  507
  Citations

• Novel computer program for fast exact calculation of accessible and molecular surface areas and average surface curvature.

  Oleg V. Tsodikov;M. Thomas Record;Yuri V. Sergeev

  481
  Citations

• Polypeptides containing highly conserved regions of transcription initiation factor σ70 exhibit specificity of binding to promoter DNA

  Alicia J. Dombroski;William A. Walter;M.Thomas Record;Deborah A. Slegele

  448
  Citations

• Role of the hydrophobic effect in stability of site-specific protein-DNA complexes.

  Unknown

  374
  Citations

• Nonspecific interaction of lac repressor with DNA: an association reaction driven by counterion release

  deHaseth Pl;Lohman Tm;Record Mt

  335
  Citations

• Biophysical compensation mechanisms buffering E. coli protein–nucleic acid interactions against changing environments

  M.Thomas Record;Elizabeth S Courtenay;Scott Cayley;Harry J Guttman

  325
  Citations

• Thermodynamic Origin of Hofmeister Ion Effects

  Laurel M. Pegram;M. Thomas Record

  322
  Citations

• Replacement of potassium chloride by potassium glutamate dramatically enhances protein-DNA interactions in vitro

  Leirmo S;Harrison C;Cayley Ds;Burgess Rr

  319
  Citations

• Contribution to the thermodynamics of protein folding from the reduction in water-accessible nonpolar surface area.

  Unknown

  316
  Citations

• Biophysical characterization of changes in amounts and activity of Escherichia coli cell and compartment water and turgor pressure in response to osmotic stress.

  D. Scott Cayley;Harry J. Guttman;M. Thomas Record

  302
  Citations

• Interpretation of monovalent and divalent cation effects on the lac repressor-operator interaction.

  Record Mt;deHaseth Pl;Lohman Tm

  296
  Citations

• Crowding and Confinement Effects on Protein Diffusion In Vivo

  Michael C. Konopka;Irina A. Shkel;Scott Cayley;M. Thomas Record

  277
  Citations

• Effects of Na+ and Mg++ ions on the helix–coil transition of DNA

  M. Thomas Record

  275
  Citations

• Salt-nucleic acid interactions.

  Unknown

  255
  Citations

• Quantifying why urea is a protein denaturant, whereas glycine betaine is a protein stabilizer.

  Emily J. Guinn;Laurel M. Pegram;Michael W. Capp;Michelle N. Pollock

  251
  Citations

• Variability of the intracellular ionic environment of Escherichia coli. Differences between in vitro and in vivo effects of ion concentrations on protein-DNA interactions and gene expression.

  Unknown

  246
  Citations

• Relative binding affinities of monovalent cations for double-stranded DNA.

  M. Louise Bleam;Charles F. Anderson;M. Thomas Record

  224
  Citations

• Temperature dependence of the rate constants of the Escherichia coli RNA polymerase-lambda PR promoter interaction. Assignment of the kinetic steps corresponding to protein conformational change and DNA opening.

  Jung-Hye Roe;Richard R. Burgess;M.Thomas Record

  221
  Citations

• Roles of Cytoplasmic Osmolytes, Water, and Crowding in the Response of Escherichia coli to Osmotic Stress: Biophysical Basis of Osmoprotection by Glycine Betaine†

  Scott Cayley;M. Thomas Record

  220
  Citations

• Thermodynamic stoichiometries of participation of water, cations and anions in specific and non-specific binding of lac repressor to DNA. Possible thermodynamic origins of the "glutamate effect" on protein-DNA interactions.

  Jeung-Hoi Ha;Michael W. Capp;Mark D. Hohenwalter;Mark Baskerville

  210
  Citations

• Thermodynamics of interactions of urea and guanidinium salts with protein surface: Relationship between solute effects on protein processes and changes in water-accessible surface area

  Elizabeth S. Courtenay;Michael W. Capp;M. Thomas Record

  206
  Citations

• Why Hofmeister effects of many salts favor protein folding but not DNA helix formation

  Laurel M. Pegram;Timothy Wendorff;Robert Erdmann;Irina Shkel

  200
  Citations

• Monte Carlo studies of counterion-DNA interactions. Comparison of the radial distribution of counterions with predictions of other polyelectrolyte theories

  Pamela Mills;Charles F. Anderson;M. Thomas Record

  198
  Citations

• Partitioning of atmospherically relevant ions between bulk water and the water/vapor interface.

  Laurel M. Pegram;M. Thomas Record

  197
  Citations