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Chemistry

D-Index
80
Citations
25205
World Ranking
3390
National Ranking
1115

Overview

Jonathan B. Chaires is affiliated with the University of Louisville in the United States. Their research is primarily situated within the fields of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology. They have contributed significantly to the study of DNA and nucleic acid chemistry, advanced biosensing and bioanalysis techniques, RNA interference and gene delivery, RNA and protein synthesis mechanisms, genomics and chromatin dynamics, thermodynamics and calorimetric analyses, and viral infectious diseases and gene expression in insects.

The scientist's recent publications span several years and are published in notable scientific venues. Among these are:

  • "The hTERT core promoter forms three parallel G-quadruplexes" (2020) published in Nucleic Acids Research
  • "G-quadruplex DNA: A Longer Story" (2022) published in Accounts of Chemical Research
  • "The solution structures of higher-order human telomere G-quadruplex multimers" (2021) published in Nucleic Acids Research
  • "Long promoter sequences form higher-order G-quadruplexes: an integrative structural biology study of c-Myc, k-Ras and c-Kit promoter sequences" (2022) published in Nucleic Acids Research
  • "Human POT1 unfolds G-quadruplexes by conformational selection" (2020) published in Nucleic Acids Research

Frequent publication venues for this researcher include:

  • Nucleic Acids Research
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE
  • Accounts of Chemical Research

They have collaborated extensively with several researchers, including:

  • Robert C. Monsen
  • John O. Trent
  • Lynn DeLeeuw
  • Robert D. Gray
  • William L. Dean

Best Publications

  • Neither delta- nor lambda-tris(phenanthroline)ruthenium(II) binds to DNA by classical intercalation.

    S. Satyanarayana;James C. Dabrowiak;Jonathan B. Chaires

  • Tris(phenanthroline)ruthenium(II) enantiomer interactions with DNA: Mode and specificity of binding

    S. Satyanarayana;James C. Dabrowiak;Jonathan B. Chaires

  • Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on interaction of daunomycin with deoxyribonucleic acid.

    Jonathan B. Chaires;Nanibhushan Dattagupta;Donald M. Crothers

  • Stability and kinetics of G-quadruplex structures

    Andrew N. Lane;J. Brad Chaires;Robert D. Gray;John O. Trent

  • Sequence and structural selectivity of nucleic acid binding ligands

    Jinsong Ren;Jonathan B. Chaires

  • Interaction of Delta- and Lambda-[Ru(phen)2DPPZ]2+ with DNA: A Calorimetric and Equilibrium Binding Study

    Ihtshamul Haq;Per Lincoln;Dongchul Suh;Bengt Norden

  • Criteria for the mode of binding of DNA binding agents.

    Dongchul Suh;Jonathan B. Chaires

  • ENERGETICS OF DRUG-DNA INTERACTIONS

    Jonathan B. Chaires

  • G-Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy.

    Rafael del Villar-Guerra;John O. Trent;Jonathan B. Chaires

  • Thermal difference spectra: a specific signature for nucleic acid structures

    Jean-Louis Mergny;Jing Li;Laurent Lacroix;Samir Amrane

  • A thermodynamic signature for drug-DNA binding mode.

    Jonathan B. Chaires

  • Calorimetry and Thermodynamics in Drug Design

    Jonathan B Chaires

  • Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal

    Jing-Jing Li;John J. Correia;Lei Wang;John O. Trent

  • Sequence-specific DNA minor groove binders. Design and synthesis of netropsin and distamycin analogues.

    Christian Bailly;Jonathan B. Chaires

  • Drug--DNA interactions.

    Jonathan B Chaires

  • Circular dichroism to determine binding mode and affinity of ligand–DNA interactions

    Nichola C Garbett;Patricia A Ragazzon;Jonathan B Chaires

  • Specific binding of hoechst 33258 to the d(CGCAAATTTGCG)2 duplex: calorimetric and spectroscopic studies.

    Ihtshamul Haq;Ihtshamul Haq;John E Ladbury;Babur Z Chowdhry;Terence C Jenkins

  • Energetics of DNA intercalation reactions.

    Jinsong Ren;Terence C. Jenkins;Jonathan B. Chaires

  • Selfassociation of daunomycin

    Jonathan B. Chaires;Nanibhushan Dattagupta;Donald M. Crothers

  • Hydration is a major determinant of the G-quadruplex stability and conformation of the human telomere 3' sequence of d(AG3(TTAG3)3).

    M. Clarke Miller;Robert Buscaglia;Jonathan B. Chaires;Andrew N. Lane

  • Preferential binding of daunomycin to 5'ATCG and 5'ATGC sequences revealed by footprinting titration experiments.

    Jonathan B. Chaires;Julio E. Herrera;Michael J. Waring

Frequent Co-Authors

John O. Trent
John O. Trent University of Louisville
Jinsong Ren
Jinsong Ren Chinese Academy of Sciences
Waldemar Priebe
Waldemar Priebe The University of Texas MD Anderson Cancer Center
Xiaogang Qu
Xiaogang Qu Chinese Academy of Sciences
Michael J. Waring
Michael J. Waring University of Cambridge
Donald M. Crothers
Donald M. Crothers Yale University
Loren Dean Williams
Loren Dean Williams Georgia Institute of Technology
Babur Z. Chowdhry
Babur Z. Chowdhry University of Greenwich
Jon B. Klein
Jon B. Klein University of Louisville
James C. Dabrowiak
James C. Dabrowiak Syracuse University

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