D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 89 Citations 23,747 223 World Ranking 1265 National Ranking 535
Molecular Biology D-index 95 Citations 26,527 222 World Ranking 371 National Ranking 213

Research.com Recognitions

Awards & Achievements

1992 - Fellow of the American Association for the Advancement of Science (AAAS)

1987 - Member of the National Academy of Sciences

1978 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • DNA
  • Gene
  • Enzyme

His primary areas of study are DNA, Stereochemistry, Base pair, Biophysics and Biochemistry. His research in DNA intersects with topics in Steric effects, Molecule, Kinetics and Binding site. His Stereochemistry research incorporates themes from Covalent bond, Chromophore, Reaction rate constant, Adduct and Proflavine.

Donald M. Crothers has researched Base pair in several fields, including Nucleic acid, Crystallography, Helix, Polynucleotide and Oligonucleotide. The various areas that he examines in his Crystallography study include Curvature and Enthalpy. The concepts of his Biophysics study are interwoven with issues in Catabolite activator protein, Plasma protein binding, Molecular biology, Binding constant and DNA sequencing.

His most cited work include:

  • Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on interaction of daunomycin with deoxyribonucleic acid. (827 citations)
  • Studies of the binding of actinomycin and related compounds to DNA (721 citations)
  • The Speed of RNA Transcription and Metabolite Binding Kinetics Operate an FMN Riboswitch (356 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include DNA, Crystallography, Biochemistry, Stereochemistry and Base pair. His studies deal with areas such as Molecular biology, Biophysics, Catabolite activator protein and Binding site as well as DNA. His Crystallography study combines topics from a wide range of disciplines, such as Reaction rate constant, Kinetics, Molecule and Relaxation.

His study in Biochemistry focuses on RNA and Nucleic acid. His studies in Stereochemistry integrate themes in fields like Polynucleotide, Oligonucleotide, Intercalation and Nucleotide. His study explores the link between Base pair and topics such as Dichroism that cross with problems in Molecular physics.

He most often published in these fields:

  • DNA (42.97%)
  • Crystallography (25.70%)
  • Biochemistry (24.90%)

What were the highlights of his more recent work (between 1996-2016)?

  • DNA (42.97%)
  • Crystallography (25.70%)
  • Biophysics (18.88%)

In recent papers he was focusing on the following fields of study:

DNA, Crystallography, Biophysics, RNA and Stereochemistry are his primary areas of study. His DNA study incorporates themes from Electrophoresis, Kinetics and Binding site. His Binding site research incorporates elements of Molecular biology and Fungal protein.

His Crystallography study combines topics from a wide range of disciplines, such as Twist, Geometry, Curvature, Footprinting and Base pair. His study in Biophysics is interdisciplinary in nature, drawing from both Biochemistry, DNA-binding protein, Sense, Resolution and Antisense RNA. Donald M. Crothers works mostly in the field of Stereochemistry, limiting it down to concerns involving Agarose gel electrophoresis and, occasionally, Intercalation, Chromophore, Titration and Bromide.

Between 1996 and 2016, his most popular works were:

  • The Speed of RNA Transcription and Metabolite Binding Kinetics Operate an FMN Riboswitch (356 citations)
  • The Kinetics of Ligand Binding by an Adenine-Sensing Riboswitch (238 citations)
  • Identification and Characterization of Genomic Nucleosome-positioning Sequences (174 citations)

In his most recent research, the most cited papers focused on:

  • DNA
  • Gene
  • Enzyme

Donald M. Crothers mainly investigates RNA, DNA, Biochemistry, Nuclear magnetic resonance spectroscopy and Base pair. Donald M. Crothers interconnects Monomer, Pulsed field gradient, Nucleic acid and Analytical chemistry in the investigation of issues within RNA. His work carried out in the field of DNA brings together such families of science as Twist, Writhe and Heteronuclear molecule.

His research on Biochemistry frequently links to adjacent areas such as Biophysics. His research on Nuclear magnetic resonance spectroscopy concerns the broader Stereochemistry. His research in Base pair focuses on subjects like Bending, which are connected to Curvature, Wedge, Crystallography, A-DNA and Delocalized electron.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Studies of the binding of actinomycin and related compounds to DNA

Werner Müller;Donald M. Crothers.
Journal of Molecular Biology (1968)

1179 Citations

Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on interaction of daunomycin with deoxyribonucleic acid.

Jonathan B. Chaires;Nanibhushan Dattagupta;Donald M. Crothers.
Biochemistry (1982)

1076 Citations

Fragments of the HIV-1 Tat protein specifically bind TAR RNA

Kevin M. Weeks;Christophe Ampe;Steve C. Schultz;Thomas A. Steitz.
Science (1990)

592 Citations

Stability and properties of double and triple helices: dramatic effects of RNA or DNA backbone composition.

Richard W. Roberts;Donald M. Crothers.
Science (1992)

568 Citations

The influence of polyvalency on the binding properties of antibodies.

Donald M. Crothers;Donald M. Crothers;Henry Metzger;Henry Metzger.
Immunochemistry (1972)

545 Citations

The Speed of RNA Transcription and Metabolite Binding Kinetics Operate an FMN Riboswitch

J. Kenneth Wickiser;Wade C. Winkler;Ronald R. Breaker;Donald M. Crothers.
Molecular Cell (2005)

491 Citations

Interactions of heteroaromatic compounds with nucleic acids. 1. The influence of heteroatoms and polarizability on the base specificity of intercalating ligands.

Werner Muller;Donald M. Crothers.
FEBS Journal (1975)

463 Citations

Artificial nucleosome positioning sequences

Thomas E. Shrader;Donald M. Crothers.
Proceedings of the National Academy of Sciences of the United States of America (1989)

439 Citations

RNA recognition by Tat-derived peptides: Interaction in the major groove?

Kevin M. Weeks;Donald M. Crothers.
Cell (1991)

435 Citations

The DNA binding domain and bending angle of E. coli CAP protein

Huei-Nin Liu-Johnson;Marc R. Gartenberg;Donald M. Crothers.
Cell (1986)

413 Citations

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