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D-Index & Metrics

Chemistry

D-Index
69
Citations
17397
World Ranking
6179
National Ranking
1883

Research.com Recognitions

  • 1996 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Kenneth J. Breslauer is affiliated with Rutgers, The State University of New Jersey in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology.

The main fields of study in their work include:

  • Biochemistry, Genetics and Molecular Biology

Their subfields extend into:

  • Molecular Biology
  • Astronomy and Astrophysics
  • Cell Biology
  • Physiology
  • Radiology, Nuclear Medicine and Imaging

Kenneth J. Breslauer has published research on diverse topics such as:

  • RNA and protein synthesis mechanisms
  • DNA and Nucleic Acid Chemistry
  • Genomics and Phylogenetic Studies
  • Protein Structure and Dynamics
  • Advanced biosensing and bioanalysis techniques
  • RNA Interference and Gene Delivery
  • Origins and Evolution of Life

Some of Breslauer's recent papers include:

  • Energy mapping of the genetic code and genomic domains: implications for code evolution and molecular Darwinism, 2020, Quarterly Reviews of Biophysics
  • HSF1, Aging, and Neurodegeneration, 2022, Advances in Experimental Medicine and Biology
  • Structural and mechanistic insights into the transport of aristolochic acids and their active metabolites by human serum albumin, 2024, Journal of Biological Chemistry
  • How sequence alterations enhance the stability and delay expansion of DNA triplet repeat domains, 2023, QRB Discovery
  • Heat Capacity Changes (ΔCp) for Interconversions between Differentially-Ordered DNA States within Physiological Temperature Domains: Implications for Biological Regulatory Switches, 2020, The Journal of Physical Chemistry B

The scientist has frequently collaborated with coauthors such as:

  • Jens Völker
  • Conceição A.S.A. Minetti
  • David P. Remeta
  • Radha Bonala
  • Francis Johnson

Their work is often published in venues that include:

  • Journal of Biological Chemistry
  • Quarterly Reviews of Biophysics
  • Advances in Experimental Medicine and Biology
  • QRB Discovery
  • The Journal of Physical Chemistry B

Kenneth J. Breslauer was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 1996.

Best Publications

  • Predicting DNA duplex stability from the base sequence.

    Kenneth J. Breslauer;Ronald Frank;Helmut Blocker;Luis A. Marky

  • Calculating thermodynamic data for transitions of any molecularity from equilibrium melting curves

    Luis A. Marky;Kenneth J. Breslauer

  • The hydration of globular proteins as derived from volume and compressibility measurements: cross correlating thermodynamic and structural data.

    Tigran V. Chalikian;Maxim Totrov;Ruben Abagyan;Kenneth J. Breslauer

  • Extracting Thermodynamic Data From Equilibrium Melting Curves for Oligonucleotide Order-Disorder Transitions

    Kenneth J. Breslauer

  • A more unified picture for the thermodynamics of nucleic acid duplex melting: A characterization by calorimetric and volumetric techniques

    Tigran V. Chalikian;Jens Völker;G. Eric Plum;Kenneth J. Breslauer

  • Enthalpy-entropy compensations in drug-DNA binding studies

    Kenneth J. Breslauer;David P. Remeta;Wan-Yin Chou;Robert Ferrante

  • Salt-dependent conformational transitions in the self-complementary deoxydodecanucleotide d(CGCAATTCGCG): evidence for hairpin formation.

    Luis A. Marky;Kenneth S. Blumenfeld;Sharon Kozlowski;Kenneth J. Breslauer

  • Hydration and partial compressibility of biological compounds

    Tigran V. Chalikian;Armen P. Sarvazyan;Kenneth J. Breslauer

  • Thermodynamic characterization of the stability and the melting behavior of a DNA triplex: a spectroscopic and calorimetric study.

    G. E. Plum;Young-Whan Park;S. F. Singleton;P. B. Dervan

  • On volume changes accompanying conformational transitions of biopolymers.

    Tigran V. Chalikian;Kenneth J. Breslauer

  • Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex.

    Natasa Poklar;Daniel S. Pilch;Stephen J. Lippard;Elizabeth A. Redding

  • Partial molar volumes, expansibilities, and compressibilities of α,ω-aminocarboxylic acids in aqueous solutions between 18 and 55 °C

    Tigran V. Chalikian;Armen P. Sarvazyan;Armen P. Sarvazyan;Kenneth J. Breslauer

  • What drives proteins into the major or minor grooves of DNA

    Peter L. Privalov;Anatoly I. Dragan;Colyn Crane-Robinson;Kenneth J. Breslauer

  • Origins of netropsin binding affinity and specificity: correlations of thermodynamic and structural data.

    Luis A. Marky;Kenneth J. Breslauer

  • Thermodynamics and structure of a DNA tetraplex : a spectroscopic and calorimetric study of the tetramolecular complexes of d(TG3T) and d(TG3T2G3T)

    Renzhe Jin;Barbara L. Gaffney;Chuan Wang;Roger A. Jones

  • Influence of the Oxidatively Damaged Adduct 8-Oxodeoxyguanosine on the Conformation, Energetics, and Thermodynamic Stability of a DNA Duplex

    Plum Ge;Grollman Ap;Johnson F;Breslauer Kj

  • Spectroscopic and Calorimetric Characterizations of DNA Duplexes Containing 2-Aminopurine†

    Scott M. Law;Ramon Eritja;Myron F. Goodman;Kenneth J. Breslauer

  • The contribution of DNA single-stranded order to the thermodynamics of duplex formation.

    Gorazd Vesnaver;Kenneth J. Breslauer

  • Premelting and melting transitions in the d(CGCGAATTCGCG) self-complementary duplex in solution.

    Dinshaw J. Patel;Sharon A. Kozlowski;Janet A. Rice;Luis A. Marky

  • Influence of loop residues on the relative stabilities of DNA hairpin structures

    Mary M. Senior;Roger A. Jones;Kenneth J. Breslauer

Frequent Co-Authors

Daniel S. Pilch
Daniel S. Pilch Rutgers, The State University of New Jersey
Luis A. Marky
Luis A. Marky University of Nebraska Medical Center
Armen Sarvazyan
Armen Sarvazyan Artann Laboratories, Inc.
Roger A. Jones
Roger A. Jones Rutgers, The State University of New Jersey
Francis Johnson
Francis Johnson Stony Brook University
Arthur P. Grollman
Arthur P. Grollman Stony Brook University
Wilma K. Olson
Wilma K. Olson Rutgers, The State University of New Jersey
Stanley Stein
Stanley Stein Rutgers, The State University of New Jersey
Tigran V. Chalikian
Tigran V. Chalikian University of Toronto
Peter B. Dervan
Peter B. Dervan California Institute of Technology

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