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Tigran V. Chalikian

Tigran V. Chalikian

D-Index & Metrics

Chemistry

D-Index
43
Citations
6743
World Ranking
17234
National Ranking
464

Overview

Tigran V. Chalikian is affiliated with the University of Toronto in Canada. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with notable activity in Molecular Biology, Physical and Theoretical Chemistry, Spectroscopy, Ecology, and Materials Chemistry.

The scientist's scholarly output includes numerous publications focused on DNA and nucleic acid chemistry, RNA interference and gene delivery, and advanced biosensing and bioanalysis techniques. Additional research areas cover protein structure and dynamics, thermodynamics and calorimetric analyses, mass spectrometry techniques, and RNA and protein synthesis mechanisms.

Frequent publication venues for their work include:

  • Biophysical Journal
  • The Journal of Physical Chemistry B
  • Life
  • Biophysical Chemistry
  • Biology

Noteworthy recent papers authored or coauthored by Tigran V. Chalikian are:

  • Duplex-tetraplex equilibria in guanine- and cytosine-rich DNA, 2020, Biophysical Chemistry
  • Conformational Preferences of DNA Strands from the Promoter Region of the c-MYC Oncogene, 2020, The Journal of Physical Chemistry B
  • Volumetric Properties of Four-Stranded DNA Structures, 2021, Biology
  • Volumetric Interplay between the Conformational States Adopted by Guanine-Rich DNA from the c-MYC Promoter, 2021, The Journal of Physical Chemistry B
  • Distribution of Conformational States Adopted by DNA from the Promoter Regions of the VEGF and Bcl-2 Oncogenes, 2022, The Journal of Physical Chemistry B

Collaborations have been established with several frequent co-authors, including Lutan Liu, James W. Wells, David N. Dubins, Robert B. Macgregor, and L. Ridgway Scott. These collaborative efforts have contributed to the development and dissemination of research in their areas of expertise.

Best Publications

  • VOLUMETRIC PROPERTIES OF PROTEINS

    Tigran V Chalikian

  • The hydration of globular proteins as derived from volume and compressibility measurements: cross correlating thermodynamic and structural data.

    Tigran V. Chalikian;Maxim Totrov;Ruben Abagyan;Kenneth J. Breslauer

  • A more unified picture for the thermodynamics of nucleic acid duplex melting: A characterization by calorimetric and volumetric techniques

    Tigran V. Chalikian;Jens Völker;G. Eric Plum;Kenneth J. Breslauer

  • Characterization of pH-induced transitions of beta-lactoglobulin: ultrasonic, densimetric, and spectroscopic studies.

    Nicolas Taulier;Tigran V. Chalikian

  • Hydration and partial compressibility of biological compounds

    Tigran V. Chalikian;Armen P. Sarvazyan;Kenneth J. Breslauer

  • On volume changes accompanying conformational transitions of biopolymers.

    Tigran V. Chalikian;Kenneth J. Breslauer

  • Partial molar volumes, expansibilities, and compressibilities of α,ω-aminocarboxylic acids in aqueous solutions between 18 and 55 °C

    Tigran V. Chalikian;Armen P. Sarvazyan;Armen P. Sarvazyan;Kenneth J. Breslauer

  • Compressibility of protein transitions

    Nicolas Taulier;Tigran V. Chalikian

  • Structural Thermodynamics of Hydration

    Tigran V. Chalikian

  • Volumetric characterizations of the native, molten globule and unfolded states of cytochrome c at acidic pH.

    Tigran V. Chalikian;Vera S. Gindikin;Kenneth J. Breslauer

  • Thermodynamic analysis of biomolecules: a volumetric approach

    Tigran V Chalikian;Kenneth J Breslauer

  • Influence of base composition, base sequence, and duplex structure on DNA hydration: apparent molar volumes and apparent molar adiabatic compressibilities of synthetic and natural DNA duplexes at 25 degrees C.

    Chalikian Tv;Sarvazyan Ap;Plum Ge;Breslauer Kj

  • On the stability of double stranded nucleic acids.

    David N. Dubins;Adrian Lee;Robert B. Macgregor;Tigran V. Chalikian

  • Influence of drug binding on DNA hydration: acoustic and densimetric characterizations of netropsin binding to the poly(dAdT).poly(dAdT) and poly(dA).poly(dT) duplexes and the poly(dT).poly(dA).poly(dT) triplex at 25 degrees C.

    Chalikian Tv;Plum Ge;Sarvazyan Ap;Breslauer Kj

  • The hydration of nucleic acid duplexes as assessed by a combination of volumetric and structural techniques.

    Tigran V. Chalikian;Jens Völker;A. R. Srinivasan;Wilma K. Olson

  • Stability of DNA duplexes containing GG, CC, AA, and TT mismatches.

    Anna Tikhomirova;Irina V Beletskaya;Tigran V Chalikian

  • Partial molar volumes, expansibilities, and compressibilities of oligoglycines in aqueous solutions at 18–55°C

    Tigran V. Chalikian;Armen P. Sarvazyan;Theodor Funck;Kenneth J. Breslauer

  • Volumetric characterization of sodium-induced G-quadruplex formation.

    Helen Y. Fan;Yuen Lai Shek;Amir Amiri;David N. Dubins

  • Compressibility as a means to detect and characterize globular protein states

    Tigran V. Chalikian;Kenneth J. Breslauer

  • Association of the Minor Groove Binding Drug Hoechst 33258 with d(CGCGAATTCGCG)2: Volumetric, Calorimetric, and Spectroscopic Characterizations†

    Feixue Han;Nicolas Taulier;Tigran V. Chalikian

  • The native and the heat-induced denatured states of alpha-chymotrypsinogen A: thermodynamic and spectroscopic studies.

    Tigran V Chalikian;Jens Völker;Dan Anafi;Kenneth J Breslauer

Frequent Co-Authors

Kenneth J. Breslauer
Kenneth J. Breslauer Rutgers, The State University of New Jersey
Armen Sarvazyan
Armen Sarvazyan Artann Laboratories, Inc.
Heiko Heerklotz
Heiko Heerklotz University of Freiburg
Lewis E. Kay
Lewis E. Kay University of Toronto
Régis Pomès
Régis Pomès University of Toronto
Gregor Anderluh
Gregor Anderluh University of Ljubljana
Peter Maček
Peter Maček University of Ljubljana
Wilma K. Olson
Wilma K. Olson Rutgers, The State University of New Jersey
Giuseppe Melacini
Giuseppe Melacini McMaster University

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