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Naoto Yamaguchi

Naoto Yamaguchi

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
8345
World Ranking
17271
National Ranking
1245

Overview

Naoto Yamaguchi is affiliated with Chiba University in Japan and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research predominantly focuses on molecular biology and cell biology, with specific attention to cancer research, pathology, forensic medicine, and oncology.

The scientist's primary research topics include microtubule and mitosis dynamics, cellular transport and secretion, ubiquitin and proteasome pathways, Hippo pathway signaling and YAP/TAZ, single-cell and spatial transcriptomics, genetic factors in colorectal cancer, and cancer-related molecular mechanisms research.

Among Naoto Yamaguchi's recent publications are:

  • Vestigial-like family member 3 (VGLL3), a cofactor for TEAD transcription factors, promotes cancer cell proliferation by activating the Hippo pathway (2020, Journal of Biological Chemistry)
  • Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes (2023, Nature Biotechnology)
  • VGLL3 activates inflammatory responses by inducing interleukin-1α secretion (2021, The FASEB Journal)
  • VGLL3 increases the dependency of cancer cells on de novo nucleotide synthesis through GART expression (2022, Journal of Cellular Biochemistry)
  • Multiomic single-cell lineage tracing to dissect fate-specific gene regulatory programs (2022, bioRxiv (Cold Spring Harbor Laboratory))

The venues in which Naoto Yamaguchi frequently publishes include the Journal of Biological Chemistry, Journal of Cellular and Molecular Medicine, Cellular Signalling, Scientific Reports, and Nature Biotechnology.

Frequent collaborators in Naoto Yamaguchi's work include Noritaka Yamaguchi, Hiroyuki Takano, Yuji Nakayama, Naoto Hori, and Yuki Takakura.

Best Publications

  • Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production.

    E Sonoda;R Matsumoto;Y Hitoshi;T Ishii

  • T Cell‐Replacing Factor (TRF)/Interleukin 5 (IL‐5): Molecular and Functional Properties

    Kiyoshi Takatsu;Akira Tominaga;Nobuyuki Harada;Seiji Mita

  • Molecular cloning and expression of the murine interleukin-5 receptor.

    S. Takaki;A. Tominaga;Y. Hitoshi;S. Mita

  • Golgi retention of a trans-Golgi membrane protein, galactosyltransferase, requires cysteine and histidine residues within the membrane-anchoring domain.

    Daisuke Aoki;Ni Lee;Naoto Yamaguchi;Craig Dubois

  • Golgi retention mechanism of beta-1,4-galactosyltransferase. Membrane-spanning domain-dependent homodimerization and association with alpha- and beta-tubulins.

    Naoto Yamaguchi;Michiko N. Fukuda

  • Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain.

    Izumi Sato;Yuuki Obata;Kousuke Kasahara;Yuji Nakayama

  • The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.

    Yuta Mishima;Satoru Miyagi;Atsunori Saraya;Masamitsu Negishi

  • The role of interleukin-5 in protective immunity to Strongyloides venezuelensis infection in mice.

    M Korenaga;Y Hitoshi;N Yamaguchi;Y Sato

  • Identification of the second subunit of the murine interleukin-5 receptor: interleukin-3 receptor-like protein, AIC2B is a component of the high affinity interleukin-5 receptor.

    S. Takaki;S. Mita;T. Kitamura;S. Yonehara

  • STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family.

    Atsushi Iwama;Naoto Yamaguchi;Toshio Suda

  • Interleukin 5, a T-cell-derived B-cell differentiation factor also induces cytotoxic T lymphocytes.

    Kiyoshi Takatsu;Yuji Kikuchi;Takeo Takahashi;Tasuku Honjo

  • Distribution of IL-5 receptor-positive B cells. Expression of IL-5 receptor on Ly-1(CD5)+ B cells.

    Y Hitoshi;N Yamaguchi;S Mita;E Sonoda

  • Cost-effective gene transfection by DNA compaction at pH 4.0 using acidified, long shelf-life polyethylenimine

    Yasunori Fukumoto;Yuuki Obata;Kenichi Ishibashi;Naoki Tamura

  • Role of Src-family kinases in formation and trafficking of macropinosomes.

    Kousuke Kasahara;Yuji Nakayama;Izumi Sato;Kikuko Ikeda

  • Src Signaling Regulates Completion of Abscission in Cytokinesis through ERK/MAPK Activation at the Midbody

    Kousuke Kasahara;Yuji Nakayama;Yoshimi Nakazato;Kikuko Ikeda

  • Terminal differentiation of murine resident peritoneal macrophages is characterized by expression of the STK protein tyrosine kinase, a receptor for macrophage-stimulating protein.

    Atsushi Iwama;Ming Hai Wang;Naoto Yamaguchi;Noriko Ohno

  • Characterization of high-affinity receptors for interleukin 5 on interleukin 5-dependent cell lines.

    Seiji Mita;Akira Tominaga;Yasumichi Hitoshi;Kiyoshi Sakamoto

  • Rapid trafficking of c-Src, a non-palmitoylated Src-family kinase, between the plasma membrane and late endosomes/lysosomes.

    Kousuke Kasahara;Yuji Nakayama;Akio Kihara;Daisuke Matsuda

  • Role of macrophage-stimulating protein and its receptor, RON tyrosine kinase, in ciliary motility.

    Osamu Sakamoto;Atsushi Iwama;Ryoichi Amitani;Toyohiro Takehara

  • A common signaling pathway via Syk and Lyn tyrosine kinases generated from capping of the sialomucins CD34 and CD43 in immature hematopoietic cells.

    Jun Ichi Tada;Jun Ichi Tada;Mitsuhiro Omine;Mitsuhiro Omine;Toshio Suda;Toshio Suda;Naoto Yamaguchi

Frequent Co-Authors

Kiyoshi Takatsu
Kiyoshi Takatsu University of Toyama
Toshio Suda
Toshio Suda National University of Singapore
Atsushi Iwama
Atsushi Iwama University of Tokyo
Eiichiro Sonoda
Eiichiro Sonoda Kyoto University
Masami Ishibashi
Masami Ishibashi Chiba University
Haruhiko Koseki
Haruhiko Koseki RIKEN Center for Integrative Medical Sciences
Ichiro Matsuda
Ichiro Matsuda Kumamoto University
Masayuki Ando
Masayuki Ando Kumamoto University
Naoto Oku
Naoto Oku University of Shizuoka
Toshihide Yamashita
Toshihide Yamashita Osaka University

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