2023 - Research.com Medicine in Japan Leader Award
His primary areas of study are Cell biology, Genetics, Molecular biology, Polycomb-group proteins and PRC2. His work deals with themes such as Cellular differentiation, T cell, Immunology, Enhancer and Cytotoxic T cell, which intersect with Cell biology. His studies deal with areas such as Haematopoiesis, CD44 and Cancer research as well as Immunology.
His Genetics study is mostly concerned with Chromatin, PRC1, Gene, Regulation of gene expression and Epigenetics. His Molecular biology study combines topics in areas such as CD40, CD74, Reprogramming, Antigen processing and T-cell receptor. His study focuses on the intersection of Polycomb-group proteins and fields such as Histone H2A with connections in the field of X-inactivation and Computational biology.
The scientist’s investigation covers issues in Cell biology, Molecular biology, Genetics, Gene and Stem cell. His Cell biology study integrates concerns from other disciplines, such as Embryonic stem cell, Cellular differentiation and Chromatin, PRC1, Epigenetics. His Chromatin research integrates issues from Histone and Gene expression.
His Molecular biology research also works with subjects such as
Haruhiko Koseki mainly investigates Cell biology, Chromatin, Epigenetics, Gene and Gene expression. His Cell biology research includes elements of PRC2, DNA methylation, Transcription factor, PRC1 and Regulation of gene expression. His research in Chromatin intersects with topics in Sonic hedgehog, Embryonic stem cell, Morphogen and Wnt signaling pathway.
His research investigates the link between Embryonic stem cell and topics such as Polycomb-group proteins that cross with problems in Cellular differentiation. Haruhiko Koseki has researched Epigenetics in several fields, including Synapsis, Homologous chromosome, Pericentric heterochromatin and Prophase. As part of one scientific family, he deals mainly with the area of Gene, narrowing it down to issues related to the Function, and often Lysine, SUZ12, Enteric nervous system, Pathology and Megacolon.
His main research concerns Cell biology, Chromatin, Gene expression, Gene and Regulation of gene expression. His research investigates the connection between Cell biology and topics such as Epigenetics that intersect with problems in Histone deacetylase 2, HDAC1, B cell and Downregulation and upregulation. His study in PRC2 and Histone H3 is carried out as part of his Chromatin studies.
The various areas that Haruhiko Koseki examines in his Gene expression study include Phenotype, Genome, Transcription and Cell growth. Haruhiko Koseki is studying Chromatin immunoprecipitation, which is a component of Gene. Haruhiko Koseki has included themes like H3K4me3, EZH2, DNA-binding domain, RNA polymerase II and Corepressor in his Regulation of gene expression study.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
Yukihiro Furusawa;Yuuki Obata;Shinji Fukuda;Takaho A. Endo.
Nature (2013)
CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides.
Tetsu Kawano;Junqing Cui;Yasuhiko Koezuka;Isao Toura.
Science (1997)
Control of developmental regulators by Polycomb in human embryonic stem cells.
Tong Ihn Lee;Richard G. Jenner;Laurie A. Boyer;Matthew G. Guenther.
Cell (2006)
Requirement for Vα14 NKT Cells in IL-12-Mediated Rejection of Tumors
Junqing Cui;Tahiro Shin;Tetsu Kawano;Hiroshi Sato.
Science (1997)
A promoter-level mammalian expression atlas
Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie.
Nature (2014)
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
Jafar Sharif;Masahiro Muto;Shin-ichiro Takebayashi;Isao Suetake.
Nature (2007)
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains
Manching Ku;Richard P. Koche;Richard P. Koche;Richard P. Koche;Esther Rheinbay;Esther Rheinbay;Esther Rheinbay;Eric M. Mendenhall;Eric M. Mendenhall.
PLOS Genetics (2008)
Polycomb Group Proteins Ring1A/B Link Ubiquitylation of Histone H2A to Heritable Gene Silencing and X Inactivation
Mariana de Napoles;Jacqueline E. Mermoud;Rika Wakao;Y.Amy Tang.
Developmental Cell (2004)
Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells
Julie K. Stock;Sara Giadrossi;Miguel Casanova;Emily Brookes.
Nature Cell Biology (2007)
Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells
Tetsu Kawano;Junqing Cui;Yasuhiko Koezuka;Isao Toura.
Proceedings of the National Academy of Sciences of the United States of America (1998)
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