D-Index & Metrics Best Publications
Medicine
Japan
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 108 Citations 50,549 444 World Ranking 3474 National Ranking 70
Molecular Biology D-index 109 Citations 50,976 452 World Ranking 213 National Ranking 15

Research.com Recognitions

Awards & Achievements

2023 - Research.com Medicine in Japan Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His primary areas of study are Cell biology, Genetics, Molecular biology, Polycomb-group proteins and PRC2. His work deals with themes such as Cellular differentiation, T cell, Immunology, Enhancer and Cytotoxic T cell, which intersect with Cell biology. His studies deal with areas such as Haematopoiesis, CD44 and Cancer research as well as Immunology.

His Genetics study is mostly concerned with Chromatin, PRC1, Gene, Regulation of gene expression and Epigenetics. His Molecular biology study combines topics in areas such as CD40, CD74, Reprogramming, Antigen processing and T-cell receptor. His study focuses on the intersection of Polycomb-group proteins and fields such as Histone H2A with connections in the field of X-inactivation and Computational biology.

His most cited work include:

  • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells (2330 citations)
  • CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. (2191 citations)
  • Control of developmental regulators by Polycomb in human embryonic stem cells. (2007 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Molecular biology, Genetics, Gene and Stem cell. His Cell biology study integrates concerns from other disciplines, such as Embryonic stem cell, Cellular differentiation and Chromatin, PRC1, Epigenetics. His Chromatin research integrates issues from Histone and Gene expression.

His Molecular biology research also works with subjects such as

  • T-cell receptor which connect with Alpha,
  • Cytotoxic T cell which is related to area like T cell. His study in PRC2, Polycomb-group proteins, Hox gene, Transcription factor and Enhancer are all subfields of Genetics. His Haematopoiesis research is multidisciplinary, incorporating elements of Myeloid, Cancer research and Bone marrow.

He most often published in these fields:

  • Cell biology (42.70%)
  • Molecular biology (25.75%)
  • Genetics (20.39%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (42.70%)
  • Chromatin (10.73%)
  • Epigenetics (10.52%)

In recent papers he was focusing on the following fields of study:

Haruhiko Koseki mainly investigates Cell biology, Chromatin, Epigenetics, Gene and Gene expression. His Cell biology research includes elements of PRC2, DNA methylation, Transcription factor, PRC1 and Regulation of gene expression. His research in Chromatin intersects with topics in Sonic hedgehog, Embryonic stem cell, Morphogen and Wnt signaling pathway.

His research investigates the link between Embryonic stem cell and topics such as Polycomb-group proteins that cross with problems in Cellular differentiation. Haruhiko Koseki has researched Epigenetics in several fields, including Synapsis, Homologous chromosome, Pericentric heterochromatin and Prophase. As part of one scientific family, he deals mainly with the area of Gene, narrowing it down to issues related to the Function, and often Lysine, SUZ12, Enteric nervous system, Pathology and Megacolon.

Between 2018 and 2021, his most popular works were:

  • Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression (83 citations)
  • PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation. (51 citations)
  • Functional annotation of human long noncoding RNAs via molecular phenotyping (28 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His main research concerns Cell biology, Chromatin, Gene expression, Gene and Regulation of gene expression. His research investigates the connection between Cell biology and topics such as Epigenetics that intersect with problems in Histone deacetylase 2, HDAC1, B cell and Downregulation and upregulation. His study in PRC2 and Histone H3 is carried out as part of his Chromatin studies.

The various areas that Haruhiko Koseki examines in his Gene expression study include Phenotype, Genome, Transcription and Cell growth. Haruhiko Koseki is studying Chromatin immunoprecipitation, which is a component of Gene. Haruhiko Koseki has included themes like H3K4me3, EZH2, DNA-binding domain, RNA polymerase II and Corepressor in his Regulation of gene expression study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Yukihiro Furusawa;Yuuki Obata;Shinji Fukuda;Takaho A. Endo.
Nature (2013)

3724 Citations

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides.

Tetsu Kawano;Junqing Cui;Yasuhiko Koezuka;Isao Toura.
Science (1997)

3709 Citations

Control of developmental regulators by Polycomb in human embryonic stem cells.

Tong Ihn Lee;Richard G. Jenner;Laurie A. Boyer;Matthew G. Guenther.
Cell (2006)

2597 Citations

Requirement for Vα14 NKT Cells in IL-12-Mediated Rejection of Tumors

Junqing Cui;Tahiro Shin;Tetsu Kawano;Hiroshi Sato.
Science (1997)

1884 Citations

A promoter-level mammalian expression atlas

Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie.
Nature (2014)

1550 Citations

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

Jafar Sharif;Masahiro Muto;Shin-ichiro Takebayashi;Isao Suetake.
Nature (2007)

1265 Citations

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

Manching Ku;Richard P. Koche;Richard P. Koche;Richard P. Koche;Esther Rheinbay;Esther Rheinbay;Esther Rheinbay;Eric M. Mendenhall;Eric M. Mendenhall.
PLOS Genetics (2008)

1083 Citations

Polycomb Group Proteins Ring1A/B Link Ubiquitylation of Histone H2A to Heritable Gene Silencing and X Inactivation

Mariana de Napoles;Jacqueline E. Mermoud;Rika Wakao;Y.Amy Tang.
Developmental Cell (2004)

1000 Citations

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

Julie K. Stock;Sara Giadrossi;Miguel Casanova;Emily Brookes.
Nature Cell Biology (2007)

737 Citations

Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells

Tetsu Kawano;Junqing Cui;Yasuhiko Koezuka;Isao Toura.
Proceedings of the National Academy of Sciences of the United States of America (1998)

705 Citations

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