World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
98
Citations
52554
World Ranking
770
National Ranking
438

Medicine

D-Index
98
Citations
52557
World Ranking
8757
National Ranking
4516

Overview

Luc Van Kaer is affiliated with Vanderbilt University Medical Center in the United States. Their research primarily spans the fields of Immunology and Microbiology as well as Medicine, with a significant focus on Immunology as a subfield. Other subfields of study include Epidemiology, Molecular Biology, Physiology, and Oncology.

The scientist's research topics cover a range of areas related to immune system function and regulation. These include:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Autophagy in Disease and Therapy
  • IL-33, ST2, and ILC Pathways
  • Phagocytosis and Immune Regulation
  • Dermatology and Skin Diseases
  • Immunotherapy and Immune Responses

Van Kaer's recent published papers are as follows:

  • Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition, 2020, Nature Neuroscience
  • Autophagy-related protein PIK3C3/VPS34 controls T cell metabolism and function, 2020, Autophagy
  • NKG2A Is a Therapeutic Vulnerability in Immunotherapy Resistant MHC-I Heterogeneous Triple-Negative Breast Cancer, 2023, Cancer Discovery
  • Understanding ER+ Breast Cancer Dormancy Using Bioinspired Synthetic Matrices for Long-Term 3D Culture and Insights into Late Recurrence, 2020, Advanced Biosystems
  • Innate and Innate-like Effector Lymphocytes in Health and Disease, 2022, The Journal of Immunology

Frequent co-authors in Van Kaer's publications include Lan Wu, Seokmann Hong, Hyun Jung Park, Sung Won Lee, and Guan Yang.

The scientist has contributed to the following publication venues multiple times:

  • The Journal of Immunology (8 publications)
  • Frontiers in Immunology (8 publications)
  • International Journal of Molecular Sciences (6 publications)
  • Autophagy (4 publications)
  • Proceedings of the National Academy of Sciences (3 publications)

Van Kaer has also authored a book titled Therapeutic Potential of Innate and Innate-like Effector Lymphocytes in Autoimmune and Inflammatory Diseases, published in 2023 by Frontiers Media.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • NKT cells: what's in a name?

    Dale I Godfrey;H Robson MacDonald;Mitchell Kronenberg;Mark J Smyth

  • The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Receptor Expression on NKT Cells

    Hidemitsu Kitamura;Kenji Iwakabe;Takashi Yahata;Shin-ichiro Nishimura

  • Evidence for a differential avidity model of T cell selection in the thymus

    Philip G. Ashton-Rickardt;Antonio Bandeira;Joseph R. Delaney;Luc Van Kaer

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells.

    Luc Van Kaer;Luc Van Kaer;Philip G. Ashton-Rickardt;Philip G. Ashton-Rickardt;Hidde L. Ploegh;Susumu Tonegawa;Susumu Tonegawa

  • The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice.

    Seokmann Hong;Michael T. Wilson;Isao Serizawa;Lan Wu

  • CD1d1 Mutant Mice Are Deficient in Natural T Cells That PromptlyProduce IL-4

    Sanjeev K Mendiratta;W.David Martin;Seokmann Hong;Alina Boesteanu

  • Critical contribution of liver natural killer T cells to a murine model of hepatitis.

    Kazuyoshi Takeda;Yoshihiro Hayakawa;Luc Van Kaer;Hironori Matsuda

  • Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits.

    Thomas A. Griffin;Dipankar Nandi;Miguel Cruz;Hans Jörg Fehling

  • Glycolipid antigen induces long-term natural killer T cell anergy in mice

    Vrajesh V. Parekh;Michael T. Wilson;Danyvid Olivares-Villagómez;Avneesh K. Singh

  • Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.

    Avneesh K. Singh;Michael T. Wilson;Seokmann Hong;Danyvid Olivares-Villagómez

  • Organ-specific features of natural killer cells

    Fu-Dong Shi;Fu-Dong Shi;Hans-Gustaf Ljunggren;Antonio La Cava;Luc Van Kaer

  • Cutting Edge: Activation of NK T Cells by CD1d and α-Galactosylceramide Directs Conventional T Cells to the Acquisition of a Th2 Phenotype

    Nagendra Singh;Seokmann Hong;David C. Scherer;David C. Scherer;Isao Serizawa

  • Natural Killer T Cell Ligand α-Galactosylceramide Enhances Protective Immunity Induced by Malaria Vaccines

    Gloria Gonzalez-Aseguinolaza;Luc Van Kaer;Cornelia C. Bergmann;James M. Wilson

  • The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion.

    Michael T. Wilson;Cecilia Johansson;Danyvid Olivares-Villagómez;Avneesh K. Singh

  • alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles.

    Luc Van Kaer

  • H2-M Mutant Mice Are Defective in the Peptide Loading of Class II Molecules, Antigen Presentation, and T Cell Repertoire Selection

    W.David Martin;Geoffrey G Hicks;Sanjeev K Mendiratta;Hitesh I Leva

  • Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus

    Philip G. Ashton-Rickardt;Luc Van Kaer;Ton N.M. Schumacher;Hidde L. Ploegh

  • Erratum: Organ-specific features of natural killer cells

    Fu-Dong Shi;Hans-Gustaf Ljunggren;Antonio La Cava;Luc Van Kaer

Frequent Co-Authors

Sebastian Joyce
Sebastian Joyce Vanderbilt University Medical Center
Fu-Dong Shi
Fu-Dong Shi Tianjin Medical University General Hospital
Ko Okumura
Ko Okumura Juntendo University
Antonio La Cava
Antonio La Cava University of California, Los Angeles
Hans-Gustaf Ljunggren
Hans-Gustaf Ljunggren Karolinska Institute
Hideo Yagita
Hideo Yagita Juntendo University
Hidde L. Ploegh
Hidde L. Ploegh Boston Children's Hospital
Yasuhiko Koezuka
Yasuhiko Koezuka Vanderbilt University
Keith T. Wilson
Keith T. Wilson Vanderbilt University Medical Center

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