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Immunology

D-Index
56
Citations
11004
World Ranking
3725
National Ranking
36

Overview

Fu-Dong Shi is affiliated with Tianjin Medical University General Hospital in China. Their research predominantly falls within the broad field of Medicine, with a substantial focus on Neurology, Pathology and Forensic Medicine, Immunology, Molecular Biology, and Rheumatology. Throughout their career, they have contributed extensively to the scientific understanding of various neurological and immunological disorders.

Their work covers several main topics, including:

  • Multiple Sclerosis Research Studies
  • Peripheral Neuropathies and Disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Acute Ischemic Stroke Management
  • Systemic Lupus Erythematosus Research
  • Myasthenia Gravis and Thymoma
  • Intracerebral and Subarachnoid Hemorrhage Research

Shi has frequently published in several key venues, notably:

  • The Lancet Regional Health - Western Pacific
  • Multiple Sclerosis and Related Disorders
  • Annals of Clinical and Translational Neurology
  • Journal of Neuroinflammation
  • Stroke and Vascular Neurology

Among recent papers associated with Shi, the following stand out:

  • Safety and efficacy of tocilizumab versus azathioprine in highly relapsing neuromyelitis optica spectrum disorder (TANGO): an open-label, multicentre, randomised, phase 2 trial (2020, The Lancet Neurology)
  • Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition (2020, Nature Neuroscience)
  • tPA Mobilizes Immune Cells That Exacerbate Hemorrhagic Transformation in Stroke (2020, Circulation Research)
  • Bone marrow hematopoiesis drives multiple sclerosis progression (2022, Cell)
  • The Efficacy and Safety of Remimazolam Tosilate versus Etomidate-Propofol in Elderly Outpatients Undergoing Colonoscopy: A Prospective, Randomized, Single-Blind, Non-Inferiority Trial (2021, Drug Design Development and Therapy)

Shi's research collaborations include repeated partnerships with several coauthors, such as:

  • De-Cai Tian
  • Xinghu Zhang
  • Kaibin Shi
  • Yongjun Wang
  • Qiang Liu

Additionally, Fu-Dong Shi has contributed to book publications. One notable work published by Frontiers Media in 2023 is Therapeutic Potential of Innate and Innate-like Effector Lymphocytes in Autoimmune and Inflammatory Diseases.

Best Publications

  • Global brain inflammation in stroke.

    Kaibin Shi;De-Cai Tian;Zhi-Guo Li;Andrew F Ducruet

  • Organ-specific features of natural killer cells

    Fu-Dong Shi;Fu-Dong Shi;Hans-Gustaf Ljunggren;Antonio La Cava;Luc Van Kaer

  • Fingolimod for the treatment of intracerebral hemorrhage: a 2-arm proof-of-concept study.

    Ying Fu;Junwei Hao;Ningnannan Zhang;Li Ren

  • Impact of an immune modulator fingolimod on acute ischemic stroke.

    Ying Fu;Ningnannan Zhang;Li Ren;Yaping Yan

  • Safety and efficacy of tocilizumab versus azathioprine in highly relapsing neuromyelitis optica spectrum disorder (TANGO): an open-label, multicentre, randomised, phase 2 trial.

    Chao Zhang;Meini Zhang;Wei Qiu;Hongshan Ma

  • Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology.

    Junwei Hao;Ruolan Liu;Wenhua Piao;Qinghua Zhou

  • IL-18 Directs Autoreactive T Cells and Promotes Autodestruction in the Central Nervous System Via Induction of IFN-γ by NK Cells

    Fu-Dong Shi;Fu-Dong Shi;Kiyoshi Takeda;Shizuo Akira;Nora Sarvetnick

  • Natural killer cells determine the outcome of B cell–mediated autoimmunity

    Shi Fd;Shi Fd;Wang Hb;Li H;Hong S

  • Induction of Antigen-Specific Tolerance in Multiple Sclerosis After Immunization With DNA Encoding Myelin Basic Protein in a Randomized, Placebo-Controlled Phase 1/2 Trial

    Amit Bar-Or;Timothy Vollmer;Jack Antel;Douglas L. Arnold

  • Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity

    Minshu Li;Zhiguo Li;Yang Yao;Wei-Na Jin;Wei-Na Jin

  • Differential Effects of IL-21 during Initiation and Progression of Autoimmunity against Neuroantigen

    Timothy L. Vollmer;Ruolan Liu;Mary Price;Susan Rhodes

  • tPA Mobilizes Immune Cells That Exacerbate Hemorrhagic Transformation in Stroke

    Kaibin Shi;Kaibin Shi;Ming Zou;Dong-Mei Jia;Samuel Shi

  • Reciprocal regulation between natural killer cells and autoreactive T cells.

    Fu-Dong Shi;Luc Van Kaer

  • Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition

    Wei-Na Jin;Wei-Na Jin;Kaibin Shi;Wenyan He;Jun-Hong Sun

  • Responsiveness to reduced dosage of rituximab in Chinese patients with neuromyelitis optica

    Chun-Sheng Yang;Li Yang;Ting Li;Da-Qi Zhang

  • Colony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage

    Minshu Li;Zhiguo Li;Honglei Ren;Wei-Na Jin;Wei-Na Jin

  • mTORC1 pathway disruption ameliorates brain inflammation following stroke via a shift in microglia phenotype from M1 type to M2 type

    Daojing Li;Chunjiong Wang;Yang Yao;Li Chen

  • Dissemination of brain inflammation in traumatic brain injury.

    Kaibin Shi;Jianning Zhang;Jing-Fei Dong;Fu-Dong Shi;Fu-Dong Shi;Fu-Dong Shi

  • Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation

    Qiang Liu;Qiang Liu;Nader Sanai;Wei-Na Jin;Wei-Na Jin;Antonio La Cava

  • Nicotinic Attenuation of Central Nervous System Inflammation and Autoimmunity

    Fu-Dong Shi;Wen-Hua Piao;Yen-Ping Kuo;Denise I. Campagnolo

  • Natural killer cells in human autoimmunity.

    Malin Flodström-Tullberg;Yenan T Bryceson;Fu-Dong Shi;Petter Höglund

  • IL-17 Promotes Murine Lupus

    Gil Amarilyo;Elaine V. Lourenço;Fu-Dong Shi;Antonio La Cava

  • Erratum: Organ-specific features of natural killer cells

    Fu-Dong Shi;Hans-Gustaf Ljunggren;Antonio La Cava;Luc Van Kaer

Frequent Co-Authors

Qiang Liu
Qiang Liu Chinese Academy of Sciences
Hans Link
Hans Link Karolinska Institute
Timothy Vollmer
Timothy Vollmer University of Florida
Antonio La Cava
Antonio La Cava University of California, Los Angeles
Xue-Feng Bai
Xue-Feng Bai The Ohio State University
Hans-Gustaf Ljunggren
Hans-Gustaf Ljunggren Karolinska Institute
Chunshui Yu
Chunshui Yu Tianjin Medical University General Hospital
Bao-Guo Xiao
Bao-Guo Xiao Fudan University
Luc Van Kaer
Luc Van Kaer Vanderbilt University Medical Center
Nora Sarvetnick
Nora Sarvetnick University of Nebraska Medical Center

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