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Biology and Biochemistry

D-Index
69
Citations
16275
World Ranking
7427
National Ranking
3387

Overview

Kim Boekelheide is a researcher affiliated with Brown University in the United States. Their work primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on several specialized subfields including Molecular Biology, Small Animals, Health, Toxicology and Mutagenesis, Pharmacology, and Biomedical Engineering.

Their research addresses multiple key topics such as Animal testing and alternatives, Effects and risks of endocrine disrupting chemicals, Pharmacogenetics and Drug Metabolism, 3D Printing in Biomedical Research, Viral Infectious Diseases and Gene Expression in Insects, Molecular Biology Techniques and Applications, and Computational Drug Discovery Methods.

Boekelheide's recent publications illustrate the scope and focus of their research. Notable papers include:

  • "Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients," 2021, Regulatory Toxicology and Pharmacology
  • "Adverse effects in traditional and alternative toxicity tests," 2024, Regulatory Toxicology and Pharmacology
  • "Highly conserved sperm function-related transcripts across three species: human, rat and mouse," 2021, Reproductive Toxicology
  • "Development of a human liver microphysiological coculture system for higher throughput chemical safety assessment," 2024, Toxicological Sciences
  • "A novel co-culture model of human prostate epithelial and stromal cells for androgenic and antiandrogenic screening," 2023, Toxicology in Vitro

The venues in which Boekelheide frequently publishes include Regulatory Toxicology and Pharmacology, Reproductive Toxicology, Toxicological Sciences, Toxicology in Vitro, and Scientific Reports.

Collaboration forms a part of Boekelheide's research environment, with several frequent co-authors such as Samantha J. Madnick, Paul L. Carmichael, Susan J. Hall, Matthew Dent, and Russell S. Thomas.

Best Publications

  • TOXICITY TESTING IN THE 21ST CENTURY: A VISION AND A STRATEGY

    Daniel Krewski;Daniel Acosta;Melvin Andersen;Henry Anderson

  • The Fas System is a Key Regulator of Germ Cell Apoptosis in the Testis

    Jeongwu Lee;J. H. Richburg;S. C. Younkin;K. Boekelheide

  • The Mammalian SIR2α Protein Has a Role in Embryogenesis and Gametogenesis

    Michael W. McBurney;Xiaofeng Yang;Karen Jardine;Mary Hixon

  • NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di-n-butyl phthalate ☆

    Robert Kavlock;Kim Boekelheide;Robert Chapin;Michael Cunningham

  • NTP‐CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A

    Robert E. Chapin;Jane Adams;Kim Boekelheide;L. Earl Gray

  • Selective Protein Covalent Binding and Target Organ Toxicity

    Steven D. Cohen;Neil R. Pumford;Edward A. Khairallah;Kim Boekelheide

  • The Fas System, a Regulator of Testicular Germ Cell Apoptosis, Is Differentially Up-Regulated in Sertoli Cell Versus Germ Cell Injury of the Testis

    Jeongwu Lee;John H. Richburg;Elizabeth B. Shipp;Marvin L. Meistrich

  • Mono-(2-ethylhexyl) Phthalate Rapidly Alters both Sertoli Cell Vimentin Filaments and Germ Cell Apoptosis in Young Rat Testes

    John H. Richburg;Kim Boekelheide

  • Toxicity Testing in the 21st Century: Progress in the Past Decade and Future Perspectives

    D. Krewski;M. E. Andersen;M. G. Tyshenko;K. Krishnan

  • Mechanisms of Toxic Damage to Spermatogenesis

    Kim Boekelheide

  • Toxicity Testing in the 21st Century: Defining New Risk Assessment Approaches Based on Perturbation of Intracellular Toxicity Pathways

    Sudin Bhattacharya;Qiang Zhang;Paul L. Carmichael;Kim Boekelheide

  • NTP-CERHR Expert Panel Update on the Reproductive and Developmental Toxicity of di(2-ethylhexyl) phthalate.

    Robert Kavlock;Dana Barr;Kim Boekelheide;William Breslin

  • Predicting Later-Life Outcomes of Early-Life Exposures

    Kim Boekelheide;Bruce Blumberg;Robert E. Chapin;Ila Cote

  • Studies of the molecular pathogenesis of hexane neuropathy. II. Evidence that pyrrole derivatization of lysyl residues leads to protein crosslinking.

    Doyle G. Graham;D. Carter Anthony;Kim Boekelheide;Natalie A. Maschmann

  • NTP center for the evaluation of risks to human reproduction

    Robert Kavlock;Kim Boekelheide;Robert Chapin;Michael Cunningham

  • Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene.

    Susannah Varmuza;Andrea Jurisicova;Kazuhiro Okano;John Hudson

  • Of mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent.

    Kamin J. Johnson;Nicholas E. Heger;Kim Boekelheide

  • Exposure In Utero to Di(n-Butyl) Phthalate Alters the Vimentin Cytoskeleton of Fetal Rat Sertoli Cells and Disrupts Sertoli Cell-Gonocyte Contact

    Elena Kleymenova;Cynthia Swanson;Kim Boekelheide;Kevin W. Gaido

  • Fetal mouse phthalate exposure shows that gonocyte multinucleation is not associated with decreased testicular testosterone

    Kevin W. Gaido;Janan B. Hensley;Delong Liu;Duncan G. Wallace

  • Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand.

    John H. Richburg;Adrian Nañez;Lisa R. Williams;Michelle E. Embree

Frequent Co-Authors

Melvin E. Andersen
Melvin E. Andersen Research Triangle Park Foundation
Thomas Hartung
Thomas Hartung Johns Hopkins University
Susan M. Huse
Susan M. Huse Brown University
Robert E. Chapin
Robert E. Chapin Pfizer (United States)
Michael W. McBurney
Michael W. McBurney University of Ottawa
E. Andres Houseman
E. Andres Houseman Oregon State University
Albert J. Fornace
Albert J. Fornace Georgetown University
Jeffrey R. Morgan
Jeffrey R. Morgan Brown University
Dwaine F. Emerich
Dwaine F. Emerich Alkermes (Ireland)
John M. Sedivy
John M. Sedivy Brown University

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