World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
14266
World Ranking
13043
National Ranking
5562

Overview

Thomas B. Knudsen is affiliated with the Environmental Protection Agency in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a notable emphasis on molecular biology as a key subfield. Their work also spans pediatrics, perinatology and child health, small animals, biomedical engineering, and biochemistry.

Their scholarly contributions address several main topics that include:

  • Pluripotent Stem Cells Research
  • Animal testing and alternatives
  • Retinoids in leukemia and cellular processes
  • 3D Printing in Biomedical Research
  • Pharmaceutical studies and practices
  • Antioxidant Activity and Oxidative Stress
  • Estrogen and related hormone effects

Knudsen has published extensively in various scientific venues. The most frequent venues for their publications are:

  • Birth Defects Research
  • OPAL (Open@LaTrobe) (La Trobe University)
  • Reproductive Toxicology
  • Toxicological Sciences
  • Current Research in Toxicology

Their recent papers reflect a focus on developmental toxicity, systemic toxicity prediction, neural tube closure, and the transition from animal models to new testing methods. Notable recent publications include:

  • FutureTox IV Workshop Summary: Predictive Toxicology for Healthy Children (2021, Toxicological Sciences)
  • Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity (2020, Toxicological Sciences)
  • New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop (2020, Regulatory Toxicology and Pharmacology)
  • An ontology for developmental processes and toxicities of neural tube closure (2020, Reproductive Toxicology)
  • Protecting Human and Animal Health: The Road from Animal Models to New Approach Methods (2024, Pharmacological Reviews)

Collaborative efforts are reflected in their frequent co-authorship with several researchers, including:

  • Nicole Kleinstreuer
  • Nancy Baker
  • Kristin Artinger
  • Sue Marty
  • Sonja A. Rasmussen

Best Publications

  • Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function.

    Vassilios Papadopoulos;Mario Baraldi;Tomás R. Guilarte;Thomas B. Knudsen

  • Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework

    Edward J. Calabrese;Kenneth A. Bachmann;A. John Bailer;P. Michael Bolger

  • In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project

    Richard S. Judson;Keith A. Houck;Robert J. Kavlock;Thomas B. Knudsen

  • ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology

    Ann M. Richard;Richard S. Judson;Keith A. Houck;Christopher M. Grulke

  • Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management

    Robert Kavlock;Kelly Chandler;Keith Houck;Sid Hunter

  • The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency

    Russell S Thomas;Tina Bahadori;Timothy J Buckley;John Cowden

  • Endocrine profiling and prioritization of environmental chemicals using ToxCast data.

    David M. Reif;Matthew T. Martin;Shirlee W. Tan;Keith A. Houck

  • Zebrafish developmental screening of the ToxCast™ Phase I chemical library.

    S. Padilla;D. Corum;B. Padnos;D.L. Hunter

  • Zebrafish: as an integrative model for twenty-first century toxicity testing.

    Nisha S. Sipes;Nisha S. Sipes;Stephanie Padilla;Thomas B. Knudsen

  • Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High Throughput Screening Assays for the Estrogen Receptor

    Richard S. Judson;Felicia Maria Magpantay;Vijay Chickarmane;Cymra Haskell

  • High-Throughput Models for Exposure-Based Chemical Prioritization in the ExpoCast Project

    John F. Wambaugh;R. Woodrow Setzer;David M. Reif;Sumit Gangwal

  • Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

    Richard Judson;Keith Houck;Matt Martin;Ann M. Richard

  • A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing.

    David A. Basketter;Harvey Clewell;Ian Kimber;Annamaria Rossi

  • Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment.

    Richard S Judson;Robert J Kavlock;R Woodrow Setzer;Elaine A Cohen Hubal

  • Analysis of Eight Oil Spill Dispersants Using Rapid, In Vitro Tests for Endocrine and Other Biological Activity

    Richard S. Judson;Matthew T. Martin;David M. Reif;Keith A. Houck

  • Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays.

    Nisha Schuler Sipes;Matthew Thomas Martin;Parth Kothiya;David M. Reif

  • Predictive Models of Prenatal Developmental Toxicity from ToxCast High-Throughput Screening Data

    Nisha S. Sipes;Matthew T. Martin;David M. Reif;Nicole C. Kleinstreuer

  • Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms

    Nicole C Kleinstreuer;Jian Yang;Ellen L Berg;Thomas B Knudsen

  • Reprogramming of genetic networks during initiation of the Fetal Alcohol Syndrome

    Maia L. Green;Maia L. Green;Amar V. Singh;Amar V. Singh;Yihzi Zhang;Kimberly A. Nemeth

  • Consensus report on the future of animal-free systemic toxicity testing.

    Marcel Leist;Nina Hasiwa;Costanza Rovida;Mardas Daneshian

Frequent Co-Authors

Aldert H. Piersma
Aldert H. Piersma Centre for Health Protection
Kevin M. Crofton
Kevin M. Crofton R3Fellows LLC
Menghang Xia
Menghang Xia National Institutes of Health
Thomas Hartung
Thomas Hartung Johns Hopkins University
Ruili Huang
Ruili Huang National Institutes of Health
Linda F. Thompson
Linda F. Thompson Oklahoma Medical Research Foundation
Marcel Leist
Marcel Leist University of Konstanz
Michael R. Blackburn
Michael R. Blackburn The University of Texas Health Science Center at Houston
Jan-Åke Gustafsson
Jan-Åke Gustafsson University of Houston
David A. Basketter
David A. Basketter University of Bedfordshire

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology and Biochemistry in the USA opens doors to a range of diverse and rewarding career options, many of which can be pursued through flexible online learning. For those interested in health and nutrition, online nutrition degrees are becoming increasingly popular, offering foundational knowledge in dietetics, health promotion, and food science. Graduates may work in wellness coaching, public health, or as nutrition consultants.

Students seeking leadership positions in healthcare may consider cahme accredited online mha programs, which are designed to build management and organizational skills for roles in hospitals, clinics, and healthcare systems. At the doctoral level, professionals looking to advance their clinical expertise without extensive clinical hours can benefit from the best online dnp programs.

Additionally, those interested in strategic or executive healthcare roles may pursue a doctorate in healthcare management. These programs prepare graduates for high-level positions in policy, administration, and academic research, matching perfectly with the evolving landscape of healthcare careers.

Best Scientists Citing Thomas B. Knudsen

Trending Scientists