World's Best Scientists 2026 revealed!

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Medicine

D-Index
97
Citations
36728
World Ranking
9241
National Ranking
4769

Research.com Recognitions

  • 2016 - Fellow, National Academy of Inventors
  • 2012 - Distinguished Scientist Award, American Heart Association
  • 2001 - Member of the National Academy of Medicine (NAM)
  • 1985 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Warren M. Zapol is affiliated with Harvard University in the United States. Their research spans primarily the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on pulmonary and respiratory medicine, molecular biology, endocrine systems, physiology, and genetics.

The scientist's research topics cover a range of areas including respiratory support and mechanisms, neonatal respiratory health research, neuroscience of respiration and sleep, neonatal health and biochemistry, mitochondrial function and pathology, metabolism and genetic disorders, and cardiac arrest and resuscitation.

Frequent publication venues for Warren M. Zapol include Nitric Oxide, Lasers in Surgery and Medicine, Journal of Visualized Experiments, UNC Libraries, and Nature Biotechnology.

Selected recent papers demonstrate a focus on respiratory and biochemical mechanisms:

  • "An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance" (2020, Nature Biotechnology)
  • "High Concentrations of Nitric Oxide Inhalation Therapy in Pregnant Patients With Severe Coronavirus Disease 2019 (COVID-19)" (2020, Obstetrics and Gynecology)
  • "Airway stem cells sense hypoxia and differentiate into protective solitary neuroendocrine cells" (2020, Science)
  • "Inhaled high dose nitric oxide is a safe and effective respiratory treatment in spontaneous breathing hospitalized patients with COVID-19 pneumonia" (2021, Nitric Oxide)
  • "Antimicrobial effects of nitric oxide in murine models of Klebsiella pneumonia" (2020, Redox Biology)

Collaboration has been a notable component of their career, with frequent coauthors including Lorenzo Berra, Fumito Ichinose, Ryan W. Carroll, Donald B. Bloch, and Steffen B. Wiegand.

Warren M. Zapol has been recognized by several organizations, receiving the Distinguished Scientist Award from the American Heart Association in 2012, being named a Fellow of the American Association for the Advancement of Science in 1985, elected as a Member of the National Academy of Medicine in 2001, and named Fellow of the National Academy of Inventors in 2016.

Best Publications

  • Inhaled Nitric Oxide for the Adult Respiratory Distress Syndrome

    Rolf Rossaint;Konrad J. Falke;Frank Lopez;Klaus Slama

  • Extracorporeal membrane oxygenation in severe acute respiratory failure. A randomized prospective study.

    W M Zapol;M T Snider;J D Hill;R J Fallat

  • Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Failure. A Randomized Prospective Study

    W. M. Zapol;M. T. Snider;J. D. Hill;R. J. Fallat

  • Inhaled Nitric Oxide: A Selective Pulmonary Vasodilator Reversing Hypoxic Pulmonary Vasoconstriction

    C. Frostell;M. D. Fratacci;J. C. Wain;R. Jones

  • Inhaled Nitric Oxide and Persistent Pulmonary Hypertension of the Newborn

    Jesse D. Roberts;Jeffrey R. Fineman;Frederick C. Morin;Philip W. Shaul

  • Inhaled nitric oxide in persistent pulmonary hypertension of the newborn

    J D Roberts;D M Polaner;P Lang;W M Zapol

  • Pulmonary Hypertension in Severe Acute Respiratory Failure

    Warren M. Zapol;Michael T. Snider

  • Acute left ventricular dysfunction during unsuccessful weaning from mechanical ventilation.

    Francois Lemaire;Jean-Louis Teboul;Luc Cinotti;Guillen Giotto

  • Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation.

    Claes G. Frostell;Hans Blomqvist;Göran Hedenstierna;Jan Lundberg

  • The pulmonary vascular lesions of the adult respiratory distress syndrome.

    J. F. Tomashefski;P. Davies;C. Boggis;R. Greene

  • Inhaled Nitric Oxide in Congenital Heart Disease

    Jesse D. Roberts;Peter Lang;Luca M. Bigatello;Gus J. Vlahakes

  • Inhaled nitric oxide: a selective pulmonary vasodilator: current uses and therapeutic potential

    Fumito Ichinose;Jesse D. Roberts;Warren M. Zapol

  • Hypoxia as a therapy for mitochondrial disease

    Isha H. Jain;Luca Zazzeron;Rahul Goli;Rahul Goli;Kristen Alexa

  • Bronchodilator Action of Inhaled Nitric Oxide in Guinea Pigs

    P. M. Dupuy;S. A. Shore;J. M. Drazen;C. Frostell

  • The rise of oxygen over the past 205 million years and the evolution of large placental mammals.

    Paul G. Falkowski;Miriam E. Katz;Allen J. Milligan;Katja Fennel

  • Inhaled nitric oxide. A selective pulmonary vasodilator of heparin-protamine vasoconstriction in sheep.

    Marie-Dominique Fratacci;Claes G. Frostell;Tong-Yen Chen;John C. Wain

  • Endothelial Nitric Oxide Synthase Limits Left Ventricular Remodeling After Myocardial Infarction in Mice

    Marielle Scherrer-Crosbie;Roman Ullrich;Kenneth D. Bloch;Hiroshi Nakajima

  • Prolonged inhalation of low concentrations of nitric oxide in patients with severe adult respiratory distress syndrome. Effects on pulmonary hemodynamics and oxygenation.

    Luca M. Bigatello;William E. Hurford;Robert M. Kacmarek;Jesse D. Roberts

  • Regional blood flow during simulated diving in the conscious Weddell seal

    W. M. Zapol;G. C. Liggins;R. C. Schneider;J. Qvist

  • Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3.

    W Steudel;Marielle Scherrer-Crosbie;K D Bloch;J Weimann

Frequent Co-Authors

Kenneth D. Bloch
Kenneth D. Bloch Harvard University
Vamsi K. Mootha
Vamsi K. Mootha Harvard Medical School
Robert M. Kacmarek
Robert M. Kacmarek Harvard University
Peter W. Hochachka
Peter W. Hochachka University of British Columbia
Michael H. Picard
Michael H. Picard Harvard University
Lynne Reid
Lynne Reid Harvard University
Martin Feelisch
Martin Feelisch University of Southampton
Anthony Rosenzweig
Anthony Rosenzweig Harvard University
John C. Wain
John C. Wain Harvard University

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