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Biology and Biochemistry

D-Index
80
Citations
17148
World Ranking
4186
National Ranking
2048

Overview

Stephen M. Black is affiliated with Florida International University in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a particular focus on pulmonary and respiratory medicine and molecular biology.

The scientist has contributed extensively to topics including:

  • Pulmonary Hypertension Research and Treatments
  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research
  • Nitric Oxide and Endothelin Effects
  • Cancer, Hypoxia, and Metabolism
  • Inhalation and Respiratory Drug Delivery
  • Eicosanoids and Hypertension Pharmacology

Among their recent publications are:

  • Complex interplay between autophagy and oxidative stress in the development of pulmonary disease, 2020, Redox Biology
  • Metabolic reprogramming, oxidative stress, and pulmonary hypertension, 2023, Redox Biology
  • Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension, 2021, American Journal of Physiology-Cell Physiology
  • Mitochondrial network dynamics in pulmonary disease: Bridging the gap between inflammation, oxidative stress, and bioenergetics, 2024, Redox Biology
  • SARS-CoV-2 spike protein induces IL-18-mediated cardiopulmonary inflammation via reduced mitophagy, 2023, Signal Transduction and Targeted Therapy

Stephen M. Black frequently collaborates with several researchers including Ting Wang, Qing Lü, Manivannan Yegambaram, Jeffrey R. Fineman, and Haiyang Tang.

Their work is regularly published in the following venues:

  • Free Radical Biology and Medicine
  • Redox Biology
  • International Journal of Molecular Sciences
  • American Journal of Respiratory and Critical Care Medicine
  • Nitric Oxide

Their research integrates themes of oxidative stress, mitochondrial dynamics, pulmonary hypertension, and inflammation, often focusing on molecular and cellular mechanisms underlying pulmonary disease. This includes exploring the roles of autophagy, bioenergetics, and mechanosensitive channels in respiratory pathologies.

Best Publications

  • ROS Signaling in the Pathogenesis of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS).

    Manuela Kellner;Satish Noonepalle;Qing Lu;Anup Srivastava

  • Regulators of endothelial and epithelial barrier integrity and function in acute lung injury

    Rudolf Lucas;Alexander D. Verin;Stephen M. Black;John D. Catravas

  • S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity

    Kandasam Ravi;Lisa A. Brennan;Snezana Levic;Patrick A. Ross

  • eNOS activation and NO function: structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity.

    Ruslan Rafikov;Fabio V Fonseca;Sanjiv Kumar;Daniel Pardo

  • ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species

    Stephen Wedgwood;Robert W. Dettman;Stephen M. Black

  • Complex interplay between autophagy and oxidative stress in the development of pulmonary disease.

    Wojciech Ornatowski;Qing Lu;Manivannan Yegambaram;Alejandro E. Garcia

  • Increased Superoxide Generation Is Associated With Pulmonary Hypertension in Fetal Lambs. A Role for NADPH Oxidase

    Lisa A. Brennan;Robin H. Steinhorn;Stephen Wedgwood;Eugenia Mata-Greenwood

  • Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension

    Thomas Bertero;Yu Lu;Sofia Annis;Andrew Hale

  • Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit

    Thomas Bertero;Katherine A. Cottrill;Yu Lu;Christina M. Haeger

  • Carnitine homeostasis, mitochondrial function and cardiovascular disease

    Shruti Sharma;Stephen M. Black

  • Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: contributions of serine106 and P450 reductase.

    Dong Lin;Stephen M. Black;Yoshitaka Nagahama;Walter L. Miller

  • REGULATION OF NEURONAL NITRIC OXIDE SYNTHASE THROUGH ALTERNATIVE TRANSCRIPTS

    Jay E. Brenman;Houhui Xia;Daniel S. Chao;Steve M. Black

  • Endothelin-1 decreases endothelial NOS expression and activity through ETA receptor-mediated generation of hydrogen peroxide

    Stephen Wedgwood;Stephen M. Black

  • Developmental changes in murine brain antioxidant enzymes.

    Janine Y Khan;Stephen M Black

  • The role of glutathione-dependent enzymes in drug resistance.

    Stephen M. Black;C.Roland Wolf

  • Increased oxidative stress in lambs with increased pulmonary blood flow and pulmonary hypertension: role of NADPH oxidase and endothelial NO synthase

    Albert C. Grobe;Sandra M. Wells;Eileen Benavidez;Peter Oishi

  • Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.

    Haiyang Tang;Aleksandra Babicheva;Kimberly M. McDermott;Yali Gu

  • Reactive oxygen species in pulmonary vascular remodeling.

    Saurabh Aggarwal;Christine M. Gross;Shruti Sharma;Jeffrey R. Fineman

  • Activation of constitutive nitric-oxide synthase activity is an early signaling event induced by ionizing radiation.

    J. Kevin Leach;Stephen M. Black;Rupert K. Schmidt-Ullrich;Ross B. Mikkelsen

  • Construction and function of fusion enzymes of the human cytochrome P450scc system.

    Jennifer A. Harikrishna;Stephen M. Black;Grazyna D. Szklarz;Walter L. Miller

Frequent Co-Authors

John D. Catravas
John D. Catravas Old Dominion University
Jason X.-J. Yuan
Jason X.-J. Yuan University of California, San Diego
Joe G.N. Garcia
Joe G.N. Garcia University of Arizona
Ting Wang
Ting Wang Washington University in St. Louis
Alexander D. Verin
Alexander D. Verin Augusta University
David Fulton
David Fulton Augusta University
Rudolf Lucas
Rudolf Lucas Augusta University
Walter L. Miller
Walter L. Miller University of California, San Francisco
James Bristow
James Bristow Lawrence Berkeley National Laboratory
Zheng Dong
Zheng Dong Augusta University

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