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Medicine

D-Index
87
Citations
39203
World Ranking
13428
National Ranking
6830

Overview

Ivan Rusyn is affiliated with Texas A&M University in the United States and has a substantial body of research primarily in biochemistry, genetics, and molecular biology. Their work spans several subfields including health, toxicology and mutagenesis, molecular biology, cancer research, epidemiology, and biomedical engineering.

The scientist's research topics cover diverse areas such as:

  • Effects and risks of endocrine disrupting chemicals
  • Carcinogens and genotoxicity assessment
  • Liver disease diagnosis and treatment
  • Computational drug discovery methods
  • Toxic organic pollutants impact
  • 3D printing in biomedical research
  • Animal testing and alternatives

Ivan Rusyn has contributed to key publications including:

  • "The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning," 2021, Environmental Health Perspectives
  • "Emerging technologies and their impact on regulatory science," 2021, Experimental Biology and Medicine
  • "Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterization," 2021, Expert Opinion on Drug Metabolism & Toxicology
  • "Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis," 2020, Journal of Clinical Investigation
  • "Key Characteristics of Human Hepatotoxicants as a Basis for Identification and Characterization of the Causes of Liver Toxicity," 2021, Hepatology

The scientist collaborates frequently with colleagues such as Weihsueh A. Chiu, Fred A. Wright, Igor P. Pogribny, Volodymyr Tryndyak, and Lucie C. Ford.

Publication venues with multiple contributions by Ivan Rusyn include:

  • UNC Libraries
  • Toxicological Sciences
  • Toxics
  • Toxicology
  • bioRxiv (Cold Spring Harbor Laboratory)

The focus of research encompasses various aspects of toxicology and molecular mechanisms underlying disease and toxicity. The inclusion of computational methods, biomedical engineering approaches, and regulatory science reflects a multidisciplinary approach within the broad field of biochemistry, genetics, and molecular biology.

Best Publications

  • The Genotype-Tissue Expression (GTEx) project

    John Lonsdale;Jeffrey Thomas;Mike Salvatore;Rebecca Phillips

  • The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

    Kristin G. Ardlie;David S. Deluca;Ayellet V. Segrè

  • Correction: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

    Jialiang Yang;Tao Huang;Francesca Petralia;Quan Long

  • Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis.

    Martyn T. Smith;Kathryn Z. Guyton;Catherine F. Gibbons;Jason M. Fritz

  • NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

    Hiroshi Kono;Ivan I Rusyn;Ming Yin;Erwin Gäbele

  • Standardizing global gene expression analysis between laboratories and across platforms

    Theodore Bammler;Richard P. Beyer;Sanchita Bhattacharya;Gary A. Boorman

  • In vitro models for liver toxicity testing.

    Valerie Y. Soldatow;Edward L. LeCluyse;Linda G. Griffith;Ivan Rusyn

  • Role of the Kupffer Cell in Mediating Hepatic Toxicity and Carcinogenesis

    Ruth A. Roberts;Patricia E. Ganey;Changqing Ju;Lisa M. Kamendulis

  • THE ROLE OF KUPFFER CELL OXIDANT PRODUCTION IN EARLY ETHANOL-INDUCED LIVER DISEASE

    Michael D. Wheeler;Hiroshi Kono;Ming Yin;Mikio Nakagami

  • Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver

    Ivan Rusyn;Jeffrey M. Peters;Michael L. Cunningham

  • Alcohol consumption and ethyl carbamate

    Naomi Allen;Lucy M. Anderson;Frederick A. Beland;Jacques Bénichou

  • Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA).

    Christopher J. Portier;Bruce K Armstrong;Bruce C Baguley;Xaver Baur

  • Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice

    Igor P Pogribny;Athena Starlard-Davenport;Volodymyr P Tryndyak;Tao Han

  • Predicting Drug-induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches

    Yen Low;Takeki Uehara;Yohsuke Minowa;Hiroshi Yamada

  • Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat.

    Hiroshi Kono;Ivan Rusyn;Takehiko Uesugi;Shunhei Yamashina

  • Glycine: a new anti-inflammatory immunonutrient

    M. D. Wheeler;K. Ikejema;N. Enomoto;R. F. Stacklewitz

  • Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

    Jialiang Yang;Tao Huang;Francesca Petralia;Quan Long

  • Glycine and uridine prevent D-galactosamine hepatotoxicity in the rat: role of Kupffer cells.

    Robert F. Stachlewitz;Vitor Seabra;Blair Bradford;Cynthia A. Bradham

  • Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet.

    Igor P. Pogribny;Volodymyr P. Tryndyak;Tetyana V. Bagnyukova;Stepan Melnyk

  • The Genotype-Tissue Expression (GTEx) project

    John Lonsdale;Jeffrey Thomas;Mike Salvatore;Rebecca Phillips

Frequent Co-Authors

Igor P. Pogribny
Igor P. Pogribny National Center for Toxicological Research
Fred A. Wright
Fred A. Wright North Carolina State University
Ronald G. Thurman
Ronald G. Thurman University of North Carolina at Chapel Hill
David W. Threadgill
David W. Threadgill Texas A&M University
Frederick A. Beland
Frederick A. Beland National Center for Toxicological Research
Ronald P. Mason
Ronald P. Mason National Institutes of Health
Alexander Tropsha
Alexander Tropsha University of North Carolina at Chapel Hill
Ramon Bataller
Ramon Bataller University of Pittsburgh
Thomas J. McDonald
Thomas J. McDonald Texas A&M University
James A. Swenberg
James A. Swenberg University of North Carolina at Chapel Hill

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