D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 51 Citations 13,068 132 World Ranking 3507 National Ranking 1675

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Cancer

David W. Threadgill mainly focuses on Genetics, Cancer research, Inbred strain, Epidermal growth factor receptor and Phenotype. His Cancer research study incorporates themes from Carcinogenesis, Cancer, Receptor, Biochemistry and MAPK/ERK pathway. His Carcinogenesis research is multidisciplinary, relying on both WNT4 and Colorectal cancer.

His Inbred strain research includes elements of Altered Schaedler flora, Real-time polymerase chain reaction, Disease susceptibility and In vivo. His Epidermal growth factor receptor research incorporates themes from Proinflammatory cytokine, Endocrinology and Cell biology. His studies in Phenotype integrate themes in fields like Gene targeting and Recombinant DNA.

His most cited work include:

  • Targeted Disruption of Mouse EGF Receptor: Effect of Genetic Background on Mutant Phenotype (1306 citations)
  • The Collaborative Cross, a community resource for the genetic analysis of complex traits (852 citations)
  • Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function (645 citations)

What are the main themes of his work throughout his whole career to date?

David W. Threadgill mostly deals with Genetics, Internal medicine, Endocrinology, Cancer research and Epidermal growth factor receptor. His works in Gene, Allele, Inbred strain, Quantitative trait locus and Gene mapping are all subjects of inquiry into Genetics. As a part of the same scientific family, David W. Threadgill mostly works in the field of Allele, focusing on Evolutionary biology and, on occasion, Genetic drift.

When carried out as part of a general Internal medicine research project, his work on Epidermal growth factor and Obesity is frequently linked to work in Liver X receptor, therefore connecting diverse disciplines of study. His research integrates issues of Nonalcoholic fatty liver disease, Receptor, Toxicity and Cell biology in his study of Endocrinology. His work focuses on many connections between Cancer research and other disciplines, such as Colorectal cancer, that overlap with his field of interest in Carcinogenesis and Immunology.

He most often published in these fields:

  • Genetics (43.89%)
  • Internal medicine (59.41%)
  • Endocrinology (43.56%)

What were the highlights of his more recent work (between 2015-2021)?

  • Internal medicine (59.41%)
  • Endocrinology (43.56%)
  • Colorectal cancer (23.43%)

In recent papers he was focusing on the following fields of study:

Internal medicine, Endocrinology, Colorectal cancer, Steatosis and Genetics are his primary areas of study. His Internal medicine study frequently draws connections to other fields, such as Carcinogen. His work deals with themes such as Quantitative trait locus and Nonalcoholic fatty liver disease, which intersect with Endocrinology.

The concepts of his Colorectal cancer study are interwoven with issues in Oncology and Epidermal growth factor receptor. Epidermal growth factor receptor is closely attributed to Cancer research in his research. His study in Inbred strain, Allele, Locus, Genetic variation and Gene falls under the purview of Genetics.

Between 2015 and 2021, his most popular works were:

  • R2d2 drives selfish sweeps in the house mouse (42 citations)
  • The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice. (39 citations)
  • Developing gene drive technologies to eradicate invasive rodents from islands (35 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Genetics
  • DNA

His primary areas of study are Internal medicine, Endocrinology, Steatosis, Nonalcoholic fatty liver disease and Xenobiotic. David W. Threadgill combines Internal medicine and Glucagon-like peptide-2 in his studies. His Endocrinology research includes themes of Proinflammatory cytokine, PI3K/AKT/mTOR pathway, Signal transduction, Fatty liver and Parenteral nutrition.

David W. Threadgill combines subjects such as Cell, Myeloid, Inflammation, Glycolysis and Indole test with his study of Steatosis. He has included themes like Toxicity, Toxicokinetics, Drug metabolism and Methionine in his Nonalcoholic fatty liver disease study. His work carried out in the field of Carcinogen brings together such families of science as Phenotype, Gene, Metabolism and PPAR Pathway.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Targeted Disruption of Mouse EGF Receptor: Effect of Genetic Background on Mutant Phenotype

David W. Threadgill;Andrzej A. Dlugosz;Laura A. Hansen;Tamar Tennenbaum.
Science (1995)

1663 Citations

The Collaborative Cross, a community resource for the genetic analysis of complex traits

Gary A. Churchill;David C. Airey;Hooman Allayee;Joe M. Angel.
Nature Genetics (2004)

974 Citations

Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function

Elissa J Chesler;Lu Lu;Siming Shou;Yanhua Qu.
Nature Genetics (2005)

775 Citations

Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains

Sheryl S. Moy;Jessica J. Nadler;Nancy B. Young;Antonio Perez.
Behavioural Brain Research (2007)

743 Citations

The genome architecture of the collaborative cross mouse genetic reference population

Fuad A. Iraqi;Mustafa Mahajne;Yasser Salaymah;Hani Sandovski.
Genetics (2012)

551 Citations

The nature and identification of quantitative trait loci: a community's view.

Oduola Abiola;Joe M. Angel;Philip Avner;Alexander A. Bachmanov.
Nature Reviews Genetics (2003)

472 Citations

EGF Receptor is Required for KRAS-induced Pancreatic Tumorigenesis

Christine M. Ardito;Barbara M. Grüner;Kenneth K. Takeuchi;Clara Lubeseder-Martellato.
Cancer Cell (2012)

422 Citations

Role of the Angiotensin Type 2 Receptor Gene in Congenital Anomalies of the Kidney and Urinary Tract, CAKUT, of Mice and Men

Hideki Nishimura;Elizabeth Yerkes;Katharina Hohenfellner;Yoichi Miyazaki.
Molecular Cell (1999)

371 Citations

Genomic analysis of the major bovine milk protein genes.

David W. Threadgill;James E. Womack.
Nucleic Acids Research (1990)

370 Citations

Genetic analysis of complex traits in the emerging Collaborative Cross

David L. Aylor;William Valdar;Wendy Foulds-Mathes;Ryan J. Buus.
Genome Research (2011)

330 Citations

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