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David W. Threadgill

David W. Threadgill

D-Index & Metrics

Genetics

D-Index
73
Citations
21475
World Ranking
2034
National Ranking
932

Overview

David W. Threadgill is affiliated with Texas A&M University in the United States. Their research spans several areas within biochemistry, genetics, molecular biology, and medicine, contributing extensively to the understanding of molecular and genetic mechanisms across various biological systems.

The scientist's publication record includes papers focusing on diet, metabolism, genetics, immunity, and microbiota relationships. Some recent publications are:

  • Indole Alleviates Diet-Induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3 (2020, Hepatology)
  • Genetic and metabolic links between the murine microbiome and memory (2020, Microbiome)
  • Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research (2020, Genetics)
  • Transcriptional Correlates of Tolerance and Lethality in Mice Predict Ebola Virus Disease Patient Outcomes (2020, Cell Reports)
  • Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2 (2021, EMBO Reports)

Threadgill frequently collaborates with several researchers including:

  • Fernando Pardo-Manuel de Villena
  • Helene Andrews-Polymenis
  • Andrew Hillhouse
  • Aravindh Nagarajan
  • L. Garry Adams

The scientist publishes regularly in venues such as:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Genetics
  • Microbiome
  • Research Square (Research Square)

David W. Threadgill's main fields of study include Biochemistry, Genetics and Molecular Biology, with 122 publications, and Medicine, with 118 publications. Their work also covers subfields such as Molecular Biology, Genetics, Physiology, Infectious Diseases, and Oncology.

Key research topics addressed in their work include:

  • Diet and metabolism studies
  • Gut microbiota and health
  • Genetic Mapping and Diversity in Plants and Animals
  • Adipose Tissue and Metabolism
  • Salmonella and Campylobacter epidemiology
  • Genetic and phenotypic traits in livestock
  • CRISPR and Genetic Engineering

Best Publications

  • Targeted Disruption of Mouse EGF Receptor: Effect of Genetic Background on Mutant Phenotype

    David W. Threadgill;Andrzej A. Dlugosz;Laura A. Hansen;Tamar Tennenbaum

  • The Collaborative Cross, a community resource for the genetic analysis of complex traits

    Gary A. Churchill;David C. Airey;Hooman Allayee;Joe M. Angel

  • Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains

    Sheryl S. Moy;Jessica J. Nadler;Nancy B. Young;Antonio Perez

  • Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function

    Elissa J Chesler;Lu Lu;Siming Shou;Yanhua Qu

  • The genome architecture of the collaborative cross mouse genetic reference population

    Fuad A. Iraqi;Mustafa Mahajne;Yasser Salaymah;Hani Sandovski

  • The nature and identification of quantitative trait loci: a community's view.

    Oduola Abiola;Joe M. Angel;Philip Avner;Alexander A. Bachmanov

  • EGF Receptor is Required for KRAS-induced Pancreatic Tumorigenesis

    Christine M. Ardito;Barbara M. Grüner;Kenneth K. Takeuchi;Clara Lubeseder-Martellato

  • A Gnotobiotic Mouse Model Demonstrates that Dietary Fiber Protects Against Colorectal Tumorigenesis in a Microbiota- and Butyrate-Dependent Manner

    Dallas R. Donohoe;Darcy Holley;Leonard B. Collins;Stephanie A. Montgomery

  • Genetic analysis of complex traits in the emerging Collaborative Cross

    David L. Aylor;William Valdar;Wendy Foulds-Mathes;Ryan J. Buus

  • Genomic analysis of the major bovine milk protein genes.

    David W. Threadgill;James E. Womack

  • Role of the Angiotensin Type 2 Receptor Gene in Congenital Anomalies of the Kidney and Urinary Tract, CAKUT, of Mice and Men

    Hideki Nishimura;Elizabeth Yerkes;Katharina Hohenfellner;Yoichi Miyazaki

  • Luteinizing Hormone-Dependent Activation of the Epidermal Growth Factor Network Is Essential for Ovulation

    Minnie Hsieh;Daekee Lee;Sara Panigone;Kathleen Horner

  • Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer

    Sergio Kaiser;Young Kyu Park;Jeffrey L. Franklin;Richard B. Halberg

  • Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis

    Reade B. Roberts;Lu Min;M. Kay Washington;Sandra J. Olsen

  • The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics.

    Elissa J. Chesler;Darla R. Miller;Lisa R. Branstetter;Leslie D. Galloway

  • EGFR Signaling Promotes TGFβ-Dependent Renal Fibrosis

    Jianchun Chen;Jian Kang Chen;Kojiro Nagai;David Plieth

  • Ten years of the Collaborative Cross.

    David W. Threadgill;Gary A. Churchill

  • The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics

    Adam Roberts;Fernando Pardo-Manuel de Villena;Wei Wang;Leonard McMillan

  • Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development

    Laura A. Hansen;Natalie Alexander;Margaret E. Hogan;John P. Sundberg

  • Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain

    David W. Threadgill;David W. Threadgill;Delia Yee;Argabin Matin;Joseph H. Nadeau

Frequent Co-Authors

Fernando Pardo-Manuel de Villena
Fernando Pardo-Manuel de Villena University of North Carolina at Chapel Hill
Leonard McMillan
Leonard McMillan University of North Carolina at Chapel Hill
Gary A. Churchill
Gary A. Churchill The Jackson Laboratory
Daniel Pomp
Daniel Pomp University of North Carolina at Chapel Hill
Ivan Rusyn
Ivan Rusyn Texas A&M University
Elissa J. Chesler
Elissa J. Chesler University of Tennessee at Knoxville
Terry Magnuson
Terry Magnuson University of North Carolina at Chapel Hill
James E. Womack
James E. Womack Texas A&M University
Robert J. Coffey
Robert J. Coffey Vanderbilt University Medical Center
Robert W. Williams
Robert W. Williams University of Tennessee Health Science Center

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