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Microbiology

D-Index
52
Citations
10158
World Ranking
4197
National Ranking
287

Overview

Klaus Schughart is affiliated with the Helmholtz Centre for Infection Research in Germany. Their research portfolio encompasses a broad spectrum of topics within medicine, with a primary focus on epidemiology, immunology, molecular biology, infectious diseases, and pulmonary and respiratory medicine.

The scientist has contributed extensively to studies on influenza virus and related immune responses. The main topics covered in their work include:

  • Influenza Virus Research Studies
  • Interferon and Immune Responses
  • Respiratory Viral Infections Research
  • Immune Response and Inflammation
  • SARS-CoV-2 and COVID-19 Research
  • Respiratory Support and Mechanisms
  • Neonatal Respiratory Health Research

Several recent papers illustrate the breadth of Klaus Schughart's scientific contributions. Among them are:

  • "Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection" (2022), published in PLoS Pathogens
  • "Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross" (2020), published in Cell Reports
  • "Blood transcriptome analysis of patients with uncomplicated bacterial infection and sepsis" (2021), published in BMC Research Notes
  • "Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways" (2020), published in Journal of Biological Chemistry
  • "Long-Term Consequence of Non-neurotropic H3N2 Influenza A Virus Infection for the Progression of Alzheimer's Disease Symptoms" (2021), published in Frontiers in Cellular Neuroscience

Klaus Schughart has frequently collaborated with a number of other researchers, including:

  • Federico Armando
  • Robert Geffers
  • Heike Kollmus
  • Wolfgang Baumgärtner
  • Mark T. Heise

The scientist's work appears in multiple publication venues, notably:

  • UNC Libraries
  • Tierärztliche Praxis Ausgabe K Kleintiere / Heimtiere
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • BMC Genomic Data

Best Publications

  • Genome-wide, large-scale production of mutant mice by ENU mutagenesis

    M. H. Hrabe de Angelis;H. Flaswinkel;H. Fuchs;B. Rathkolb

  • The genome architecture of the collaborative cross mouse genetic reference population

    Fuad A. Iraqi;Mustafa Mahajne;Yasser Salaymah;Hani Sandovski

  • The mouse Pax21Neu mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney

    Jack Favor;Rodica Sandulache;Angelika Neuhäuser-Klaus;Walter Pretsch

  • THE EXPRESSION OF THE MOUSE ZIC1, ZIC2, AND ZIC3 GENE SUGGESTS AN ESSENTIAL ROLE FOR ZIC GENES IN BODY PATTERN FORMATION

    Takeharu Nagai;Jun Aruga;Shinji Takada;Thomas Günther

  • Two steps in the evolution of Antennapedia-class vertebrate homeobox genes.

    Claudia Kappen;Klaus Schughart;Frank H. Ruddle

  • TMPRSS2 and TMPRSS4 Facilitate Trypsin-Independent Spread of Influenza Virus in Caco-2 Cells

    Stephanie Bertram;Ilona Glowacka;Paulina Blazejewska;Elizabeth Soilleux

  • Long-term neuroinflammation induced by influenza A virus infection and the impact on hippocampal neuron morphology and function

    Shirin Hosseini;Esther Wilk;Kristin Michaelsen-Preusse;Ingo Gerhauser

  • Host genetic background strongly influences the response to influenza a virus infections.

    Barkha Srivastava;Paulina Błażejewska;Manuela Heßmann;Dunja Bruder

  • Tmprss2 Is Essential for Influenza H1N1 Virus Pathogenesis in Mice

    Bastian Hatesuer;Stephanie Bertram;Nora Mehnert;Mahmoud M. Bahgat

  • Mouse Hox-2.2 specifies thoracic segmental identity in Drosophila embryos and larvae

    Jarema Malicki;Klaus Schughart;William McGinnis

  • Hoxd-12 differentially affects preaxial and postaxial chondrogenic branches in the limb and regulates Sonic hedgehog in a positive feedback loop

    V. Knezevic;R. De Santo;K. Schughart;U. Huffstadt

  • Early evolutionary origin of major homeodomain sequence classes.

    Claudia Kappen;Klaus Schughart;Frank H. Ruddle

  • Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection

    Benjamin M Tang;Maryam Shojaei;Sally Teoh;Adrienne Meyers

  • Duplication of large genomic regions during the evolution of vertebrate homeobox genes.

    Klaus Schughart;Claudia Kappen;Frank H. Ruddle

  • Lim1 activity is required for intermediate mesoderm differentiation in the mouse embryo.

    Tania E Tsang;William Shawlot;Simon J Kinder;Akio Kobayashi;Akio Kobayashi

  • A novel immune biomarker IFI27 discriminates between influenza and bacteria in patients with suspected respiratory infection.

    Benjamin M. Tang;Maryam Shojaei;Grant P. Parnell;Stephen Huang

  • Characterization and expression pattern of the frizzled gene Fzd9, the mouse homolog of FZD9 which is deleted in Williams-Beuren syndrome.

    Yu-Ker Wang;Ralf Spörle;Tamar Paperna;Klaus Schughart

  • Global Transcriptome Analysis in Influenza-Infected Mouse Lungs Reveals the Kinetics of Innate and Adaptive Host Immune Responses

    Claudia Pommerenke;Esther Wilk;Barkha Srivastava;Annika Schulze

  • Retinoic Acid Receptor α Function in Vertebrate Limb Skeletogenesis: a Modulator of Chondrogenesis

    David E. Cash;Cheryl B. Bock;Klaus Schughart;Elwood Linney

  • Homeobox genes in mouse development.

    C. S. Shashikant;M. F. Utset;S. M. Violette;T. L. Wise

Frequent Co-Authors

Robert Geffers
Robert Geffers Helmholtz Centre for Infection Research
Frank H. Ruddle
Frank H. Ruddle Yale University
Rainer Bischoff
Rainer Bischoff University of Groningen
Rudi Balling
Rudi Balling University of Bonn
Robert W. Williams
Robert W. Williams University of Tennessee Health Science Center
Morris A. Swertz
Morris A. Swertz University Medical Center Groningen
Paul N. Schofield
Paul N. Schofield University of Cambridge
Damian Smedley
Damian Smedley Queen Mary University of London
Stefan Pöhlmann
Stefan Pöhlmann German Primate Center
Ritsert C. Jansen
Ritsert C. Jansen University of Groningen

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