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Brent R. Stockwell

Brent R. Stockwell

D-Index & Metrics

Biology and Biochemistry

D-Index
108
Citations
112997
World Ranking
1024
National Ranking
617

Overview

Brent R. Stockwell is affiliated with Columbia University in the United States. Their research primarily spans fields such as Biochemistry, Genetics and Molecular Biology, with a significant focus also on Medicine.

The research subfields in which Brent R. Stockwell has contributed frequently include Molecular Biology, Pulmonary and Respiratory Medicine, Cancer Research, Infectious Diseases, and Immunology.

The scientist's work covers several main topics, notably:

  • Ferroptosis and cancer prognosis
  • RNA modifications and cancer
  • Cancer, Lipids, and Metabolism
  • Cancer-related molecular mechanisms research
  • Epigenetics and DNA Methylation
  • Computational Drug Discovery Methods
  • SARS-CoV-2 and COVID-19 Research

Brent R. Stockwell has published extensively in various journals. Their frequent publication venues include:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Nature Cell Biology
  • Cell chemical biology

Highlighted recent papers authored or coauthored by the scientist are:

  • "Ferroptosis: mechanisms, biology and role in disease," 2021, published in Nature Reviews Molecular Cell Biology
  • "Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications," 2022, published in Cell
  • "Cysteine depletion induces pancreatic tumor ferroptosis in mice," 2020, published in Science
  • "Emerging Mechanisms and Disease Relevance of Ferroptosis," 2020, published in Trends in Cell Biology
  • "Energy-stress-mediated AMPK activation inhibits ferroptosis," 2020, published in Nature Cell Biology

The scientist collaborates regularly with a group of frequent coauthors, which include Fereshteh Zandkarimi, Xuejun Jiang, Hengrui Liu, F. Forouhar, and Wei Gu.

Best Publications

  • Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

    Scott J. Dixon;Kathryn M. Lemberg;Michael R. Lamprecht;Rachid Skouta

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Regulation of Ferroptotic Cancer Cell Death by GPX4

    Wan Seok Yang;Rohitha SriRamaratnam;Matthew E. Welsch;Kenichi Shimada

  • Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

    Brent R. Stockwell;José Pedro Friedmann Angeli;Hülya Bayir;Ashley I. Bush

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Ferroptosis: mechanisms, biology and role in disease.

    Xuejun Jiang;Brent R. Stockwell;Marcus Conrad

  • Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

    Jose Pedro Friedmann Angeli;Manuela Schneider;Bettina Proneth;Yulia Y. Tyurina

  • Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

    Valerian E Kagan;Gaowei Mao;Feng Qu;Jose Pedro Friedmann Angeli

  • Ferroptosis: Death by Lipid Peroxidation

    Wan Seok Yang;Brent R. Stockwell;Brent R. Stockwell

  • The role of iron and reactive oxygen species in cell death

    Scott J Dixon;Brent R Stockwell

  • A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen

    Jason Moffat;Dorre A. Grueneberg;Xiaoping Yang;So Young Kim;So Young Kim

  • Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

    Scott J Dixon;Darpan N Patel;Matthew Welsch;Rachid Skouta

  • Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.

    Wan Seok Yang;Katherine J. Kim;Michael M. Gaschler;Milesh Patel

  • Privileged Scaffolds for Library Design and Drug Discovery

    Matthew E Welsch;Scott A Snyder;Brent R Stockwell;Brent R Stockwell

  • Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells

    Wan Seok Yang;Brent R. Stockwell

  • Lipid peroxidation in cell death.

    Michael M. Gaschler;Brent R. Stockwell

  • An Induced Proximity Model for Caspase-8 Activation

    Marta Muzio;Brent R. Stockwell;Henning R. Stennicke;Guy S. Salvesen

  • Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

    Vasanthi S. Viswanathan;Matthew J. Ryan;Harshil D. Dhruv;Shubhroz Gill

  • RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels

    Nicholas Yagoda;Moritz von Rechenberg;Elma Zaganjor;Andras J. Bauer

  • Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells

    Sonam Dolma;Stephen L Lessnick;Stephen L Lessnick;William C Hahn;William C Hahn;Brent R Stockwell

Frequent Co-Authors

Michael Foley
Michael Foley La Trobe University
Stuart L. Schreiber
Stuart L. Schreiber Harvard University
Peter Vandenabeele
Peter Vandenabeele Ghent University
Donald C. Lo
Donald C. Lo Duke University
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Marcus Conrad
Marcus Conrad Helmholtz Zentrum München
David E. Root
David E. Root Broad Institute
William C. Hahn
William C. Hahn Dana-Farber Cancer Institute
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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