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D-Index & Metrics

Neuroscience

D-Index
54
Citations
14124
World Ranking
4861
National Ranking
2192

Research.com Recognitions

  • 1994 - Fellow of Alfred P. Sloan Foundation

Overview

Donald C. Lo is affiliated with Duke University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions also in Infectious Diseases, Molecular Biology, Computational Theory and Mathematics, Epidemiology, and Public Health, Environmental and Occupational Health.

The main topics covered in their work include:

  • SARS-CoV-2 and COVID-19 Research
  • Computational Drug Discovery Methods
  • COVID-19 Clinical Research Studies
  • Autophagy in Disease and Therapy
  • Mosquito-borne diseases and control
  • Virus-based gene therapy research
  • Viral Infectious Diseases and Gene Expression in Insects

Donald C. Lo has published extensively in several venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Drug Discovery Today
  • Nature Reviews Drug Discovery
  • Human Gene Therapy
  • Chemistry - A European Journal

Recent papers include:

  • "MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling," 2020, Genes & Development
  • "RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery," 2020, SLAS DISCOVERY
  • "Drug combination therapy for emerging viral diseases," 2021, Drug Discovery Today
  • "An OpenData portal to share COVID-19 drug repurposing data in real time," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2," 2021, Frontiers in Pharmacology

Frequent co-authors collaborating with Donald C. Lo include:

  • Wei Zheng
  • Catherine Z. Chen
  • Anton Simeonov
  • Wenwei Huang
  • Xin Hu

Donald C. Lo also has book publications under Frontiers Media, including the 2023 title "Impacts of Public-Private Collaborative Research on Alzheimer's Disease: The Case of the Innovative Medicines Initiative."

Recognition in their career includes being named a Fellow of the Alfred P. Sloan Foundation in 1994.

Best Publications

  • Neurotrophins and synaptic plasticity.

    A K McAllister;L C Katz;D C Lo

  • Neurotrophins regulate dendritic growth in developing visual cortex

    A.Kimberley McAllister;Donald C. Lo;Lawrence C. Katz

  • Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth.

    A.Kimberley McAllister;A.Kimberley McAllister;Lawrence C. Katz;Lawrence C. Katz;Donald C. Lo

  • Neurotrophin regulation of cortical dendritic growth requires activity

    A.Kimberley McAllister;A.Kimberley McAllister;Lawrence C Katz;Lawrence C Katz;Donald C Lo

  • IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

    Leslie Michels Thompson;Charity T. Aiken;Linda S. Kaltenbach;Namita Agrawal

  • Truncated and full-length TrkB receptors regulate distinct modes of dendritic growth.

    Talene A. Yacoubian;Donald C. Lo

  • Neurotrophic factors and synaptic plasticity

    Donald C. Lo

  • Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins

    Benjamin G Hoffstrom;Anna Kaplan;Reka Letso;Ralf S Schmid

  • Reversal of muscle differentiation during urodele limb regeneration

    Donald C. Lo;Francesca Allen;Jeremy P. Brockes

  • Neuronal transfection in brain slices using particle-mediated gene transfer

    Donald C. Lo;A. Kimberley McAllister;Lawrence C. Katz

  • NT-4-mediated rescue of lateral geniculate neurons from effects of monocular deprivation

    David R. Riddle;Donald C. Lo;Lawrence C. Katz

  • Brain-Derived Neurotrophic Factor Differentially Regulates Excitatory and Inhibitory Synaptic Transmission in Hippocampal Cultures

    M. McLean Bolton;Andrew J. Pittman;Donald C. Lo

  • Increased expression of brain-derived neurotrophic factor induces formation of basal dendrites and axonal branching in dentate granule cells in hippocampal explant cultures.

    Steve C. Danzer;Kristy R. C. Crooks;Donald C. Lo;James O. McNamara

  • Endocytosis and synaptic removal of NR3A-containing NMDA receptors by PACSIN1/syndapin1

    Isabel Pérez-Otaño;Isabel Pérez-Otaño;Rafael Luján;Steven J Tavalin;Markus Plomann

  • Selectivity, Cocrystal Structures, and Neuroprotective Properties of Leucettines, a Family of Protein Kinase Inhibitors Derived from the Marine Sponge Alkaloid Leucettamine B.

    Tania Tahtouh;Jonathan M. Elkins;Panagis Filippakopoulos;Meera Soundararajan

  • Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington’s disease

    Rocio Gomez-Pastor;Eileen T. Burchfiel;Daniel W. Neef;Alex M. Jaeger

  • Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition

    Anan Yu;Yoko Shibata;Bijal Shah;Barbara Calamini

  • Downregulation of NR3A-Containing NMDARs Is Required for Synapse Maturation and Memory Consolidation

    Adam C. Roberts;Javier Díez-García;Ramona M. Rodriguiz;Iciar Paula López

  • Cardiac glycosides provide neuroprotection against ischemic stroke: Discovery by a brain slice-based compound screening platform

    James K. T. Wang;Stuart Portbury;Mary Beth Thomas;Shawn Barney

  • Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models

    Sonia Marco;Albert Giralt;Milos M Petrovic;Milos M Petrovic;Mahmoud A Pouladi;Mahmoud A Pouladi

  • Limit on the Role of Activity in Controlling the Release-Ready Supply of Synaptic Vesicles

    John F. Wesseling;Donald C. Lo

  • Long-Term Enhancement of Central Synaptic Transmission by Chronic Brain-Derived Neurotrophic Factor Treatment

    Nina Tang Sherwood;Donald C. Lo

Frequent Co-Authors

A. Kimberley McAllister
A. Kimberley McAllister University of California, Davis
Douglas A. Marchuk
Douglas A. Marchuk Duke University
Gillian P. Bates
Gillian P. Bates University College London
Rafael Luján
Rafael Luján University of Castilla-La Mancha
Charles F. Stevens
Charles F. Stevens Salk Institute for Biological Studies
Paul Greengard
Paul Greengard Rockefeller University
Rona K. Graham
Rona K. Graham Université de Sherbrooke
Michael D. Ehlers
Michael D. Ehlers MPM BioImpact
Lawrence C. Katz
Lawrence C. Katz Howard Hughes Medical Institute
John Landers
John Landers University of Massachusetts Chan Medical School

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