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Ernest Fraenkel

Ernest Fraenkel

MIT
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
24494
World Ranking
11097
National Ranking
4801

Ernest Fraenkel publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Ernest Fraenkel sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 171 publications — 37th percentile

37% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Ernest Fraenkel D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Ernest Fraenkel sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 61 D-Index — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Ernest Fraenkel is a researcher affiliated with MIT in the United States, specializing in the fields of Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their work spans multiple subfields including Molecular Biology, Neurology, Genetics, Cellular and Molecular Neuroscience, and Immunology.

Their research focuses on various key scientific topics such as Amyotrophic Lateral Sclerosis (ALS) Research, Neurogenetic and Muscular Disorders Research, Genetic Neurodegenerative Diseases, Single-cell and Spatial Transcriptomics, RNA Research and Splicing, Bioinformatics and Genomic Networks, and Mitochondrial Function and Pathology.

Their recent publications include the following papers:

  • "TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A" (2022), published in Nature
  • "Dictionary of immune responses to cytokines at single-cell resolution" (2023), published in Nature
  • "Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines" (2022), published in Nature Neuroscience
  • "Genome-scale screens identify factors regulating tumor cell responses to natural killer cells" (2021), published in Nature Genetics
  • "A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules" (2020), published in Scientific Reports

Frequently collaborating with peers, Fraenkel has co-authored numerous papers with the following researchers:

  • Leslie M. Thompson (22 collaborations)
  • James D. Berry (21 collaborations)
  • Steven Finkbeiner (17 collaborations)
  • Dhruv Sareen (15 collaborations)
  • Hemali Phatnani (13 collaborations)

Fraenkel's work is commonly published in notable scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory) - 21 publications
  • Nature Communications - 7 publications
  • arXiv (Cornell University) - 5 publications
  • Nature - 3 publications
  • Nature Neuroscience - 2 publications

Best Publications

  • Transcriptional Regulatory Networks in Saccharomyces cerevisiae

    Tong Ihn Lee;Nicola J. Rinaldi;François Robert;Duncan T. Odom

  • Transcriptional regulatory code of a eukaryotic genome

    Christopher T. Harbison;D. Benjamin Gordon;Tong Ihn Lee;Nicola J. Rinaldi

  • Control of Pancreas and Liver Gene Expression by HNF Transcription Factors

    Duncan T. Odom;Nora Zizlsperger;D. Benjamin Gordon;George W. Bell

  • The whole-genome landscape of medulloblastoma subtypes

    Paul A. Northcott;Paul A. Northcott;Ivo Buchhalter;Ivo Buchhalter;A. Sorana Morrissy;Volker Hovestadt

  • Foxp3 occupancy and regulation of key target genes during T-cell stimulation

    Alexander Marson;Karsten Kretschmer;Garrett M. Frampton;Elizabeth S. Jacobsen

  • An improved map of conserved regulatory sites for Saccharomyces cerevisiae

    Kenzie D MacIsaac;Ting Wang;D Benjamin Gordon;D Benjamin Gordon;David K Gifford

  • Computational discovery of gene modules and regulatory networks.

    Ziv Bar-Joseph;Georg K Gerber;Tong Ihn Lee;Nicola J Rinaldi

  • HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

    Marc L. Mendillo;Sandro Santagata;Sandro Santagata;Martina Koeva;George W. Bell

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Tissue-specific transcriptional regulation has diverged significantly between human and mouse.

    Duncan T Odom;Robin D Dowell;Elizabeth S Jacobsen;William Gordon

  • The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

    Alexandra B. Keenan;Sherry L. Jenkins;Kathleen M. Jagodnik;Simon Koplev

  • Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F–DP

    Ning Zheng;Ernest Fraenkel;Carl O. Pabo;Nikola P. Pavletich

  • Insights into GATA-1 Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis

    Ming Yu;Laura Riva;Huafeng Xie;Yocheved Schindler

  • Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity

    Esti Yeger-Lotem;Laura Riva;Linhui Julie Su;Aaron D Gitler;Aaron D Gitler

  • Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors

    Ming Yu;Tali Mazor;Hui Huang;Hsuan-Ting Huang

  • Practical Strategies for Discovering Regulatory DNA Sequence Motifs

    Kenzie D MacIsaac;Ernest Fraenkel

  • Core transcriptional regulatory circuitry in human hepatocytes

    Duncan T Odom;Robin D Dowell;Elizabeth S Jacobsen;Lena Nekludova

  • Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM

    Alan S. L. Wong;Gigi C. G. Choi;Cheryl H. Cui;Gabriela Pregernig

  • Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits

    Ryan G. Lim;Chris Quan;Andrea M. Reyes-Ortiz;Sarah E. Lutz

  • Genome-Wide Analyses Identify KIF5A as a Novel ALS Gene

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Nicola Ticozzi

Frequent Co-Authors

Leslie M. Thompson
Leslie M. Thompson University of California, Irvine
Clive N. Svendsen
Clive N. Svendsen Cedars-Sinai Medical Center
Richard A. Young
Richard A. Young MIT
David K. Gifford
David K. Gifford MIT
Alan B. Cantor
Alan B. Cantor Harvard University
Douglas A. Lauffenburger
Douglas A. Lauffenburger MIT
Susan Lindquist
Susan Lindquist MIT
Scott L. Pomeroy
Scott L. Pomeroy Boston Children's Hospital
Roger J. Davis
Roger J. Davis University of Massachusetts Chan Medical School
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco

External Links

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Best Scientists Citing Ernest Fraenkel

Stefan M. Pfister

Stefan M. Pfister

German Cancer Research Center

Publications: 74

Jens Nielsen

Jens Nielsen

Chalmers University of Technology

Publications: 59

Mark Gerstein

Mark Gerstein

Yale University

Publications: 55

Michael Snyder

Michael Snyder

Stanford University

Publications: 50

Susan Lindquist

Susan Lindquist

MIT

Publications: 47

Richard A. Young

Richard A. Young

MIT

Publications: 43

Trey Ideker

Trey Ideker

University of California, San Diego

Publications: 41

Ziv Bar-Joseph

Ziv Bar-Joseph

Carnegie Mellon University

Publications: 40

Aviv Regev

Aviv Regev

Genentech

Publications: 40

Duncan T. Odom

Duncan T. Odom

University of Cambridge

Publications: 39

Andrey Korshunov

Andrey Korshunov

German Cancer Research Center

Publications: 39

Martha L. Bulyk

Martha L. Bulyk

Harvard University

Publications: 37

David J. Waxman

David J. Waxman

Boston University

Publications: 37

Marcel Kool

Marcel Kool

German Cancer Research Center

Publications: 36

Wen-Hsiung Li

Wen-Hsiung Li

Academia Sinica

Publications: 35

Roded Sharan

Roded Sharan

Tel Aviv University

Publications: 34

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