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Wen-Hsiung Li

Wen-Hsiung Li

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Genetics
Taiwan
2026
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Genetics and Molecular Biology
Taiwan
2024

D-Index & Metrics

Genetics

D-Index
128
Citations
86885
World Ranking
270
National Ranking
1

Research.com Recognitions

  • 2026 - Research.com Genetics in Taiwan Leader Award
  • 2025 - Research.com Genetics in Taiwan Leader Award
  • 2024 - Research.com Genetics in Taiwan Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Taiwan Leader Award
  • 2023 - Research.com Genetics in Taiwan Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Taiwan Leader Award
  • 2009 - Fellow, The World Academy of Sciences
  • 2003 - International Balzan Prize
  • 2003 - Member of the National Academy of Sciences
  • 1999 - Fellow of the American Academy of Arts and Sciences

Overview

Wen-Hsiung Li is affiliated with Academia Sinica in Taiwan and has an extensive research portfolio primarily focused on biochemistry, genetics, and molecular biology, as well as agricultural and biological sciences.

The scientist's research subjects span several subfields including molecular biology, plant science, infectious diseases, genetics, and cell biology. Their work notably engages with topics such as plant molecular biology research, photosynthetic processes and mechanisms, genomics and phylogenetic studies, plant reproductive biology, fungal and yeast genetics research, GABA and rice research, and plant genetic and mutation studies.

Wen-Hsiung Li has authored multiple papers published in a range of scientific venues. Some recent publications include:

  • "Constructing a yeast to express the largest cellulosome complex on the cell surface," 2020, Proceedings of the National Academy of Sciences
  • "Maize Golden2-like transcription factors boost rice chloroplast development, photosynthesis, and grain yield," 2021, PLANT PHYSIOLOGY
  • "Origin and Evolution of Nitrogen Fixation in Prokaryotes," 2022, Molecular Biology and Evolution
  • "Rice transcription factor GAMYB modulates bHLH142 and is homeostatically regulated by TDR during anther tapetal and pollen development," 2021, Journal of Experimental Botany
  • "Behavioral and brain- transcriptomic synchronization between the two opponents of a fighting pair of the fish Betta splendens," 2020, PLoS Genetics

The following publication venues have featured their work frequently:

  • Proceedings of the National Academy of Sciences
  • Molecular Biology and Evolution
  • PLoS ONE
  • PLANT PHYSIOLOGY
  • Nature Communications

Collaboration has been a significant aspect of Wen-Hsiung Li's career, with frequent coauthors including Maurice S. B. Ku, Mei-Yeh Jade Lu, Jinn-Jy Lin, Chun-Ping Yu, and Jui-Jen Chang.

Throughout their career, Wen-Hsiung Li has been recognized by several prestigious organizations. The awards include:

  • Fellow, The World Academy of Sciences (2009)
  • International Balzan Prize (2003)
  • Member of the National Academy of Sciences (2003)
  • Fellow of the American Academy of Arts and Sciences (1999)

Best Publications

  • Mathematical model for studying genetic variation in terms of restriction endonucleases

    Masatoshi Nei;Wen-Hsiung Li

  • Statistical tests of neutrality of mutations

    Yun-Xin Fu;Wen-Hsiung Li

  • The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications.

    Paul M. Sharp;Wen-Hsiung Li

  • Fundamentals of molecular evolution

    Dan Graur;Wen-Hsiung Li

  • Rates of nucleotide substitution vary greatly among plant mitochondrial, chloroplast, and nuclear DNAs.

    Kenneth H. Wolfe;Wen-Hsiung Li;Paul M. Sharp

  • A new method for estimating synonymous and nonsynonymous rates of nucleotide substitution considering the relative likelihood of nucleotide and codon changes.

    Wen-Hsiung Li;Chung-I Wu;Chi-Cheng Luo

  • Comparative Analysis of the Receptor-Like Kinase Family in Arabidopsis and Rice

    Shin-Han Shiu;Wojciech M. Karlowski;Runsun Pan;Runsun Pan;Yun-Huei Tzeng;Yun-Huei Tzeng

  • Unbiased estimation of the rates of synonymous and nonsynonymous substitution

    Wen Hsiung Li

  • An evolutionary perspective on synonymous codon usage in unicellular organisms

    Paul M. Sharp;Wen-Hsiung Li

  • Evidence for higher rates of nucleotide substitution in rodents than in man

    Chung-I. Wu;Wen-Hsiung Li

  • Role of duplicate genes in genetic robustness against null mutations.

    Zhenglong Gu;Lars M. Steinmetz;Xun Gu;Curt Scharfe

  • Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon.

    San Hwan Chen;Geetha Habib;Chao Yuh Yang;Zi Wei Gu

  • Genomic Divergences between Humans and Other Hominoids and the Effective Population Size of the Common Ancestor of Humans and Chimpanzees

    Feng Chi Chen;Wen Hsiung Li

  • Uncovering Small RNA-Mediated Responses to Phosphate Deficiency in Arabidopsis by Deep Sequencing

    Li-Ching Hsieh;Shu-I. Lin;Arthur Chun-Chieh Shih;June-Wei Chen

  • Human polymorphism at microRNAs and microRNA target sites

    Matthew A. Saunders;Han Liang;Wen Hsiung Li

  • Mutation rates differ among regions of the mammalian genome

    Kenneth H. Wolfe;Paul M. Sharp;Wen-Hsiung Li

  • Codon usage in regulatory genes in Escherichia coli does not reflect selection for ‘rare’ codons

    Paul.M Sharp;Wen-Hsiung Li

  • Date of the monocot-dicot divergence estimated from chloroplast DNA sequence data

    Kenneth H. Wolfe;Manolo Gouy;Yau-Wen Yang;Paul M. Sharp

  • Maximum likelihood estimation of the heterogeneity of substitution rate among nucleotide sites.

    Xun Gu;Yun-Xin Fu;Wen-Hsiung Li

  • Low nucleotide diversity in man.

    Wen-Hsiung Li;Lori A. Sadler

Frequent Co-Authors

Paul M. Sharp
Paul M. Sharp University of Edinburgh
Yunxin Fu
Yunxin Fu The University of Texas Health Science Center at Houston
Lawrence Chan
Lawrence Chan Baylor College of Medicine
Shin-Han Shiu
Shin-Han Shiu Michigan State University
Masatoshi Nei
Masatoshi Nei Pennsylvania State University
Maurice S. B. Ku
Maurice S. B. Ku National Chiayi University
Chung-I Wu
Chung-I Wu Sun Yat-sen University
Kateryna D. Makova
Kateryna D. Makova Pennsylvania State University
Dan Graur
Dan Graur University of Houston
Han Liang
Han Liang The University of Texas MD Anderson Cancer Center

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