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Biology and Biochemistry

D-Index
46
Citations
8124
World Ranking
18930
National Ranking
7732

Overview

George P. Leser is affiliated with Northwestern University in the United States. Their research primarily focuses on the fields of medicine and biochemistry, genetics, and molecular biology, with particular attention to epidemiology and molecular biology as subfields.

Leser's work revolves around influenza virus research studies, vaccines and immunoinformatics approaches, as well as virology and viral diseases. These main topics illustrate a concentrated interest in understanding viral mechanisms and developing preventive strategies.

Among recent publications, George P. Leser contributed to the paper titled Repurposing Papaverine as an Antiviral Agent against Influenza Viruses and Paramyxoviruses, published in 2020 in the Journal of Virology. This article has been cited 39 times, indicating the attention it has garnered within the scientific community.

  • Megha Aggarwal
  • Robert A. Lamb

Leser frequently collaborates with Megha Aggarwal and Robert A. Lamb, highlighting collaborative partnerships in their research projects.

  • Journal of Virology

The Journal of Virology serves as a primary publication venue for Leser's work. This venue is known for publishing research related to viral biology and diseases.

Best Publications

  • Influenza Virus M2 Protein Mediates ESCRT-Independent Membrane Scission

    Jeremy S. Rossman;Jeremy S. Rossman;Xianghong Jing;George P. Leser;Robert A. Lamb;Robert A. Lamb

  • Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion

    Makoto Takeda;George P. Leser;Charles J. Russell;Robert A. Lamb

  • Influenza Virus Hemagglutinin and Neuraminidase, but Not the Matrix Protein, Are Required for Assembly and Budding of Plasmid-Derived Virus-Like Particles

    Benjamin J. Chen;George P. Leser;Eiji Morita;Robert A. Lamb

  • Ultrastructural distribution of nuclear ribonucleoproteins as visualized by immunocytochemistry on thin sections.

    S Fakan;G Leser;T E Martin

  • Influenza virus hemagglutinin and neuraminidase cytoplasmic tails control particle shape.

    Hong Jin;Hong Jin;George P. Leser;Jie Zhang;Robert A. Lamb;Robert A. Lamb

  • The Influenza Virus M2 Protein Cytoplasmic Tail Interacts with the M1 Protein and Influences Virus Assembly at the Site of Virus Budding

    Benjamin J. Chen;George P. Leser;David Jackson;Robert A. Lamb

  • Influenza virus assembly and budding in raft-derived microdomains: a quantitative analysis of the surface distribution of HA, NA and M2 proteins.

    George P. Leser;Robert A. Lamb;Robert A. Lamb

  • The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus.

    Takemasa Sakaguchi;George P. Leser;Robert A. Lamb

  • Influenza Virus M2 Ion Channel Protein Is Necessary for Filamentous Virion Formation

    Jeremy S. Rossman;Xianghong Jing;Xianghong Jing;George P. Leser;Victoria Balannik

  • The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly

    Annie M. Bruns;George P. Leser;George P. Leser;Robert A. Lamb;Robert A. Lamb;Curt M. Horvath

  • Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk

    Ping Yuan;Kurt A. Swanson;Kurt A. Swanson;George P. Leser;Reay G. Paterson

  • The Paramyxovirus SV5 V Protein Binds Two Atoms of Zinc and Is a Structural Component of Virions

    Reay G. Paterson;George P. Leser;Margaret A. Shaughnessy;Robert A. Lamb

  • Filamentous Influenza Virus Enters Cells Via Macropinocytosis

    Jeremy S. Rossman;George P. Leser;Robert A. Lamb

  • Requirements for budding of paramyxovirus simian virus 5 virus-like particles.

    Anthony P. Schmitt;George P. Leser;David L. Waning;Robert A. Lamb;Robert A. Lamb

  • Immunoelectron microscope visualization of nuclear ribonucleoprotein antigens within spread transcription complexes.

    S Fakan;G Leser;T E Martin

  • Evidence for a New Viral Late-Domain Core Sequence, FPIV, Necessary for Budding of a Paramyxovirus

    Anthony P. Schmitt;George P. Leser;Eiji Morita;Wesley I. Sundquist

  • The influenza virus hemagglutinin cytoplasmic tail is not essential for virus assembly or infectivity.

    Hong Jin;George P. Leser;Robert A. Lamb

  • Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein

    Brett D. Welch;Yuanyuan Liu;Yuanyuan Liu;Christopher A. Kors;Christopher A. Kors;George P. Leser;George P. Leser

  • Structure of the Newcastle disease virus F protein in the post-fusion conformation.

    Kurt Swanson;Xiaolin Wen;George P. Leser;Reay G. Paterson

  • Palmitylation of the influenza virus hemagglutinin (H3) is not essential for virus assembly or infectivity.

    Hong Jin;Kanta Subbarao;Sangeeta Bagai;George P. Leser

Frequent Co-Authors

Robert A. Lamb
Robert A. Lamb Northwestern University
Theodore S. Jardetzky
Theodore S. Jardetzky Stanford University
Hong Jin
Hong Jin AstraZeneca (United Kingdom)
James E. Crowe
James E. Crowe Vanderbilt University Medical Center
Robert J. Woods
Robert J. Woods University of Georgia
Michael L. Gross
Michael L. Gross Washington University in St. Louis
John V. Williams
John V. Williams University of Pittsburgh
Curt M. Horvath
Curt M. Horvath Northwestern University
Kanta Subbarao
Kanta Subbarao University of Melbourne
Ralph A. Tripp
Ralph A. Tripp University of Georgia

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