What is he best known for?
The fields of study he is best known for:
Curt M. Horvath mainly focuses on STAT protein, STAT1, Molecular biology, Cell biology and Transcription factor.
The various areas that he examines in his STAT1 study include STAT2, Alpha interferon and Tyrosine phosphorylation.
His work in STAT2 covers topics such as Virology which are related to areas like RNA Helicase A.
His Molecular biology study combines topics in areas such as DNA binding site, Binding site and DNA-binding protein.
His studies deal with areas such as Apoptosis and Biochemistry as well as Cell biology.
His Transcription factor research also works with subjects such as
- Transcription and related Phosphorylation,
- MDA5 together with Interferon.
His most cited work include:
- A Road Map for Those Who Don't Know JAK-STAT (1030 citations)
- Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice (958 citations)
- Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. (716 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Cell biology, Interferon, Virology, Molecular biology and STAT1.
His primary area of study in Cell biology is in the field of Signal transduction.
While the research belongs to areas of Interferon, he spends his time largely on the problem of Cancer research, intersecting his research to questions surrounding Janus kinase 1.
In the subject of general Virology, his work in Virus is often linked to Morbillivirus, thereby combining diverse domains of study.
His research on Molecular biology also deals with topics like
- Interferon regulatory factors that intertwine with fields like IRF3,
- DNA-binding protein which connect with Phosphorylation.
His STAT1 study integrates concerns from other disciplines, such as STAT6, STAT2, STAT protein and Interferon gamma.
He most often published in these fields:
- Cell biology (38.89%)
- Interferon (38.89%)
- Virology (37.50%)
What were the highlights of his more recent work (between 2012-2019)?
- Cell biology (38.89%)
- LGP2 (20.14%)
- MDA5 (21.53%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cell biology, LGP2, MDA5, Virology and Interferon.
Curt M. Horvath does research in Cell biology, focusing on STAT protein specifically.
His biological study spans a wide range of topics, including Molecular biology, Signal transduction and Pattern recognition receptor.
His MDA5 study is concerned with the field of Biochemistry as a whole.
The concepts of his Virology study are interwoven with issues in Acquired immune system and Innate immune system.
His research on Interferon focuses in particular on STAT1.
Between 2012 and 2019, his most popular works were:
- The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly (146 citations)
- Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway (137 citations)
- A Conserved Role for Human Nup98 in Altering Chromatin Structure and Promoting Epigenetic Transcriptional Memory (115 citations)
In his most recent research, the most cited papers focused on:
Curt M. Horvath focuses on Cell biology, Genetics, MDA5, LGP2 and RNA.
His Cell biology research incorporates themes from Reverse transcriptase, Antiviral protein, Interferon, DNA and Innate immune system.
His MDA5 research is multidisciplinary, incorporating elements of Signal transduction and Virology.
Curt M. Horvath has included themes like Pattern recognition receptor and Physiology in his Signal transduction study.
Specifically, his work in Virology is concerned with the study of Virus.
His work carried out in the field of Transcriptional regulation brings together such families of science as Transcription factor complex, STAT2, JAK-STAT signaling pathway and STAT1.
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