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D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
32781
World Ranking
2309
National Ranking
15

Overview

Thomas Decker is affiliated with the University of Vienna in Austria. Their research primarily covers fields such as Immunology and Microbiology, Biochemistry, Genetics and Molecular Biology, and Medicine. Their work extends into subfields including Immunology, Molecular Biology, Oncology, Infectious Diseases, and Ecology.

Their scholarly output focuses on topics related to interferon and immune responses, cytokine signaling pathways and interactions, immune cell function and interaction, immune cells in cancer, T-cell and B-cell immunology, RNA research and splicing, and gut microbiota and health.

Thomas Decker has published in various academic venues with multiple works in bioRxiv (Cold Spring Harbor Laboratory) and Scientific Reports. Other notable publications have appeared in Nature Communications, Nature Immunology, and Cell Death and Differentiation.

  • Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization (2020, Nature Communications)
  • JAK-STAT signaling maintains homeostasis in T cells and macrophages (2024, Nature Immunology)
  • The AP-1 transcription factors c-Jun and JunB are essential for CD8α conventional dendritic cell identity (2021, Cell Death and Differentiation)
  • Interferons reshape the 3D conformation and accessibility of macrophage chromatin (2022, iScience)
  • Cutibacterium acnes Infection Induces Type I Interferon Synthesis Through the cGAS-STING Pathway (2020, Frontiers in Immunology)

The scientist frequently collaborates with colleagues such as Mathias Müller, Matthias Farlik, Laura Boccuni, Ekaterini Platanitis, and Aarathy Ravi Sundar Jose Geetha. These collaborations have resulted in multiple joint publications.

  • Mathias Müller
  • Matthias Farlik
  • Laura Boccuni
  • Ekaterini Platanitis
  • Aarathy Ravi Sundar Jose Geetha

Best Publications

  • A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity

    Thomas Decker;Marie-Luise Lohmann-Matthes

  • JAK-STAT Signaling: From Interferons to Cytokines

    Christian Schindler;David E. Levy;Thomas Decker

  • Serine phosphorylation of STATs

    Thomas Decker;Pavel Kovarik

  • Breast cancer prognostic classification in the molecular era: the role of histological grade

    Emad A. Rakha;Jorge S. Reis-Filho;Frederick Baehner;David J. Dabbs

  • Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

    Greta Guarda;Marion Braun;Francesco Staehli;Aubry Tardivel

  • The Yin and Yang of type I interferon activity in bacterial infection

    Thomas Decker;Mathias Müller;Silvia Stockinger

  • GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression.

    Thomas Decker;Pavel Kovarik;Andreas Meinke

  • Partial Impairment of Cytokine Responses in Tyk2-Deficient Mice

    Marina Karaghiosoff;Hans Neubauer;Caroline Lassnig;Pavel Kovarik

  • Tracking heavy water (D2O) incorporation for identifying and sorting active microbial cells

    David Berry;Esther Mader;Tae Kwon Lee;Dagmar Woebken

  • Cell-associated tumor necrosis factor (TNF) as a killing mechanism of activated cytotoxic macrophages.

    T Decker;M L Lohmann-Matthes;G E Gifford

  • Comparative genomic hybridization of ductal carcinoma in situ of the breast-evidence of multiple genetic pathways.

    Horst Buerger;Friedrich Otterbach;Ronald Simon;Christopher Poremba

  • Cytoplasmic activation of GAF, an IFN-gamma-regulated DNA-binding factor.

    T Decker;DJ Lew;J Mirkovitch;Jr Je Darnell

  • Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice.

    Ryuya Yamanaka;Carrolee Barlow;Julie Lekstrom-Himes;Lucio H. Castilla

  • Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either.

    R Pine;T Decker;DS Kessler;DE Levy

  • Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock.

    Marina Karaghiosoff;Ralf Steinborn;Pavel Kovarik;Gernot Kriegshäuser

  • Buparlisib plus fulvestrant in postmenopausal women with hormone-receptor-positive, HER2-negative, advanced breast cancer progressing on or after mTOR inhibition (BELLE-3): a randomised, double-blind, placebo-controlled, phase 3 trial

    Angelo Di Leo;Stephen Johnston;Keun Seok Lee;Eva Ciruelos

  • The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.

    H. L. Pahl;B. Krauss;K. Schulze-Osthoff;T. Decker

  • Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons.

    D J Lew;T Decker;I Strehlow;J E Darnell

  • IFNs and STATs in innate immunity to microorganisms.

    Thomas Decker;Silvia Stockinger;Marina Karaghiosoff;Mathias Müller

  • Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells

    Thomas Decker;Folker Schneller;Tim Sparwasser;Theresa Tretter

Frequent Co-Authors

Mathias Müller
Mathias Müller University of Veterinary Medicine Vienna
Volker Heinemann
Volker Heinemann Ludwig-Maximilians-Universität München
Andreas Schneeweiss
Andreas Schneeweiss German Cancer Research Center
Nadia Harbeck
Nadia Harbeck Ludwig-Maximilians-Universität München
Andreas Jung
Andreas Jung University of Zurich
Werner Scheithauer
Werner Scheithauer Medical University of Vienna
Peter A. Fasching
Peter A. Fasching University of Erlangen-Nuremberg
Michael Untch
Michael Untch Helios Klinikum Berlin-Buch
Tanja Fehm
Tanja Fehm Heinrich Heine University Düsseldorf
Christian Jackisch
Christian Jackisch Breast Cancer Research Foundation

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