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Kazuya Shimoda

Kazuya Shimoda

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
13319
World Ranking
12472
National Ranking
853

Overview

Kazuya Shimoda is affiliated with the University of Miyazaki in Japan and has an extensive record of research primarily in the field of Medicine. Their research focuses on several subfields, including Genetics, Immunology, Hematology, Molecular Biology, and Ecology, Evolution, Behavior and Systematics.

The scientist's work covers a variety of main topics, notably:

  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • T-cell and Retrovirus Studies
  • Chronic Myeloid Leukemia Treatments
  • Vector-Borne Animal Diseases
  • Eosinophilic Disorders and Syndromes
  • Kruppel-like factors research
  • Acute Myeloid Leukemia Research

Kazuya Shimoda has contributed to multiple papers, some recent examples include:

  • Neoplastic fibrocytes play an essential role in bone marrow fibrosis in Jak2V617F-induced primary myelofibrosis mice (2020, Leukemia)
  • Whole-genome landscape of adult T-cell leukemia/lymphoma (2021, Blood)
  • Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers (2020, Blood)
  • Oral histone deacetylase inhibitor tucidinostat (HBI-8000) in patients with relapsed or refractory adult T-cell leukemia/lymphoma: Phase IIb results (2022, Cancer Science)
  • Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils (2021, Nature Communications)

Frequent co-authors collaborating with Kazuya Shimoda include:

  • Kotaro Shide
  • Takuro Kameda
  • Norio Komatsu
  • Yoko Kubuki
  • Keita Kirito

Their publications appear frequently in prominent venues, such as:

  • Blood
  • International Journal of Hematology
  • Clinical Lymphoma Myeloma & Leukemia
  • Annals of Hematology
  • Research Square (Research Square)

Best Publications

  • Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene.

    Kazuya Shimoda;Jan van Deursent;Mark Y. Sangster;Sally R. Sarawar

  • Integrated molecular analysis of adult T cell leukemia/lymphoma

    Keisuke Kataoka;Yasunobu Nagata;Akira Kitanaka;Yuichi Shiraishi

  • Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers

    Keisuke Kataoka;Yuichi Shiraishi;Yohei Takeda;Seiji Sakata

  • Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis.

    F W Quelle;K Shimoda;W Thierfelder;C Fischer

  • Tyk2 Plays a Restricted Role in IFNα Signaling, Although It Is Required for IL-12-Mediated T Cell Function

    Kazuya Shimoda;Kouji Kato;Kenichi Aoki;Tadashi Matsuda

  • SIMPLIFY-1: A Phase III Randomized Trial of Momelotinib Versus Ruxolitinib in Janus Kinase Inhibitor-Naïve Patients With Myelofibrosis.

    Ruben A. Mesa;Jean Jacques Kiladjian;John V. Catalano;Timothy Devos

  • A Common Genetic Polymorphism (46 C to T Substitution) in the 5′-Untranslated Region of the Coagulation Factor XII Gene Is Associated With Low Translation Efficiency and Decrease in Plasma Factor XII Level

    Taisuke Kanaji;Takashi Okamura;Koichi Osaki;Mika Kuroiwa

  • Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F

    K Shide;H K Shimoda;T Kumano;K Karube

  • Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis

    Yuko Kato;Atsushi Iwama;Yuko Tadokoro;Kazuya Shimoda

  • Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders

    Tomoya Muto;Goro Sashida;Motohiko Oshima;George R. Wendt

  • Identification of a functional receptor for granulocyte colony-stimulating factor on platelets.

    Kazuya Shimoda;Seiichi Okamura;Naoki Harada;Seiji Kondo

  • Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling

    Yosaku Watatani;Yasuharu Sato;Yasuharu Sato;Hiroaki Miyoshi;Kana Sakamoto

  • Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor

    Kazuya Shimoda;Jian Feng;Hiroshi Murakami;Shigekazu Nagata

  • Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers

    Shingo Nakahata;Tomonaga Ichikawa;Phudit Maneesaay;Yusuke Saito

  • Jaks and stats in cytokine signaling

    James N. Ihle;Tetsuya Nosaka;William Thierfelder;Frederick W. Quelle

  • Perforin gene mutations in adult-onset hemophagocytic lymphohistiocytosis.

    Koji Nagafuji;Atsushi Nonami;Takashi Kumano;Yoshikane Kikushige

  • Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma.

    Keisuke Kataoka;Masako Iwanaga;Jun Ichirou Yasunaga;Yasunobu Nagata

  • Prognostic impact of immunohistochemical biomarkers in diffuse large B-cell lymphoma in the rituximab era.

    Ritsuko Seki;Koichi Ohshima;Tomoaki Fujisaki;Naokuni Uike

  • Involvement of Tyrosine Kinase-2 in Both the IL-12/Th1 and IL-23/Th17 Axes In Vivo

    Masayuki Ishizaki;Toshihiko Akimoto;Ryuta Muromoto;Mika Yokoyama

  • Concurrent Loss Of Ezh2 and Tet2 Cooperates In The Pathogenesis Of Myelodysplastic Disorders

    Tomoya Muto;Goro Sashida;Motohiko Oshima;George R Wendt

Frequent Co-Authors

Mine Harada
Mine Harada Kyushu University
Yoshiyuki Niho
Yoshiyuki Niho Kyushu University
Koichi Akashi
Koichi Akashi Kyushu University
Tadashi Matsuda
Tadashi Matsuda Hokkaido University
Toshihiro Miyamoto
Toshihiro Miyamoto Kyushu University
Atsushi Iwama
Atsushi Iwama University of Tokyo
Seishi Ogawa
Seishi Ogawa Kyoto University
Masashi Sanada
Masashi Sanada Kyoto University
Yuichi Shiraishi
Yuichi Shiraishi University of Tokyo
Keiichi I. Nakayama
Keiichi I. Nakayama Institute of Science Tokyo

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