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Tadashi Matsuda

Tadashi Matsuda

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
28464
World Ranking
5811
National Ranking
373

Overview

Tadashi Matsuda is a researcher affiliated with Hokkaido University in Japan, with a primary focus on medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology. Their body of work includes 69 publications in medicine and 57 in immunology and microbiology, indicating a strong interdisciplinary approach to life sciences and health-related research.

The main subfields of study in their work include immunology, oncology, molecular biology, cancer research, and immunology and allergy. This diverse range reflects a specialized interest in both fundamental and applied biomedical sciences, particularly relating to immune system functions and cancer development.

The core topics addressed by their research include:

  • Cytokine Signaling Pathways and Interactions
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • NF-κB Signaling Pathways
  • Immune Response and Inflammation
  • Cell Adhesion Molecules Research
  • Interferon and Immune Responses

Among their most recent papers are:

  • "The Physiological and Pathophysiological Role of IL-6/STAT3-Mediated Signal Transduction and STAT3 Binding Partners in Therapeutic Applications", 2023, Biological and Pharmaceutical Bulletin
  • "Current understanding of the role of tyrosine kinase 2 signaling in immune responses", 2022, World Journal of Biological Chemistry
  • "Central Roles of STAT3-Mediated Signals in Onset and Development of Cancers: Tumorigenesis and Immunosurveillance", 2022, Cells
  • "Therapeutic Advantage of Tyk2 Inhibition for Treating Autoimmune and Chronic Inflammatory Diseases", 2021, Biological and Pharmaceutical Bulletin
  • "Design and Synthesis of Benzene Congeners of Resolvin E2, a Proresolving Lipid Mediator, as Its Stable Equivalents", 2020, ACS Medicinal Chemistry Letters

Their frequent coauthors indicate active collaboration in their field, including:

  • Ryuta Muromoto
  • Jun-ichi Kashiwakura
  • Yuichi Kitai
  • Kenji Oritani
  • Yuto Sasaki

Publication venues that have frequently featured their work include:

  • Biological and Pharmaceutical Bulletin
  • The Journal of Immunology
  • Biochemical and Biophysical Research Communications
  • Journal of Cosmetics Dermatological Sciences and Applications
  • Exploration of Immunology

Tadashi Matsuda's contributions lie predominantly in understanding molecular and cellular mechanisms in immune responses and cancer, with a focus on signal transduction pathways such as IL-6/STAT3 and tyrosine kinase 2 (Tyk2). Their research often intersects immunology with pharmacology and therapeutic development.

Best Publications

  • Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

    Toshio Hirano;Kiyoshi Yasukawa;Hisashi Harada;Tetsuya Taga

  • Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

    Michio Kawano;Toshio Hirano;Tadashi Matsuda;Tetsuya Taga

  • Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

    Tetsuya Taga;Masahiko Hibi;Yuuichi Hirata;Katsuhiko Yamasaki

  • IL-6 is produced by osteoblasts and induces bone resorption.

    Y Ishimi;C Miyaura;C H Jin;T Akatsu

  • Pathogenic Significance of Interleukin-6 (IL-6/BSF-2) in Castleman's Disease

    K Yoshizaki;T Matsuda;N Nishimoto;T Kuritani

  • The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells.

    Atsushi Muraguchi;Toshio Hirano;Bo Tang;Tadashi Matsuda

  • Excessive production of interleukin 6/B cell stimulatory factor‐2 in rheumatoid arthritis

    T Hirano;T Matsuda;M Turner;N Miyasaka

  • The JAK‐binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

    Hideo Yasukawa;Hiroyuki Misawa;Hiroshi Sakamoto;Masaaki Masuhara

  • IgG1 plasmacytosis in interleukin 6 transgenic mice

    Sachiko Suematsu;Tadashi Matsuda;Katsuyuki Aozasa;Shizuo Akira

  • Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene.

    K. Yasukawa;T. Hirano;Y. Watanabe;K. Muratani

  • Involvement of IL-6 in mesangial proliferative glomerulonephritis.

    Y Horii;A Muraguchi;M Iwano;T Matsuda

  • Establishment of an interleukin 6 (IL 6)/B cell stimulatory factor 2-dependent cell line and preparation of anti-IL 6 monoclonal antibodies.

    Tadashi Matsuda;Toshio Hirano And and;Tadamitsu Kishimoto

  • Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop.

    Jian Feng;Bruce A. Witthuhn;Tadashi Matsuda;Franz Kohlhuber

  • Regulation of BSF-2/IL-6 production by human mononuclear cells. Macrophage-dependent synthesis of BSF-2/IL-6 by T cells.

    Y Horii;A Muraguchi;S Suematsu;T Matsuda

  • Tyk2 Plays a Restricted Role in IFNα Signaling, Although It Is Required for IL-12-Mediated T Cell Function

    Kazuya Shimoda;Kouji Kato;Kenichi Aoki;Tadashi Matsuda

  • Differential effects of phthalate esters on transcriptional activities via human estrogen receptors α and β, and androgen receptor

    Shinji Takeuchi;Mitsuru Iida;Satoshi Kobayashi;Kazuo Jin

  • The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation.

    Tetsuya Yamamoto;Yuichi Sekine;Keiichi Kashima;Atsuko Kubota

  • Regulation of interleukin-6 expression in cultured human blood monocytes and monocyte-derived macrophages

    J Bauer;U Ganter;T Geiger;U Jacobshagen

  • Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

    Sachiko Suematsu;Taiji Matsusaka;Tadashi Matsuda;Shinsuke Ohno

  • Cross-talk between Transforming Growth Factor-β and Estrogen Receptor Signaling through Smad3

    Tadashi Matsuda;Tetsuya Yamamoto;Atsushi Muraguchi;Fahri Saatcioglu

Frequent Co-Authors

Toshio Hirano
Toshio Hirano National Institutes for Quantum and Radiological Science and Technology
Tadamitsu Kishimoto
Tadamitsu Kishimoto Osaka University
Kazuya Shimoda
Kazuya Shimoda University of Miyazaki
Akihiko Yoshimura
Akihiko Yoshimura Keio University
Mine Harada
Mine Harada Kyushu University
Shizuo Akira
Shizuo Akira Osaka University
Yuzuru Kanakura
Yuzuru Kanakura Osaka University
Keiichi I. Nakayama
Keiichi I. Nakayama Institute of Science Tokyo
Koichi Nakajima
Koichi Nakajima Osaka University
Ichiro Fujita
Ichiro Fujita Osaka University

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