Kiyoshi Yasukawa

Overview

Best Publications

• Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

  Toshio Hirano;Kiyoshi Yasukawa;Hisashi Harada;Tetsuya Taga

  2802
  Citations

• Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

  Tetsuya Taga;Masahiko Hibi;Yuuichi Hirata;Katsuhiko Yamasaki

  1827
  Citations

• Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

  Claudia Lütticken;Ursula M. Wegenka;Juping Yuan;Jan Buschmann

  1031
  Citations

• IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase

  Masaaki Murakami;Masahiko Hibi;Naoko Nakagawa;Toshimasa Nakagawa

  1001
  Citations

• Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

  Toshio Hirano;Tetsuya Taga;Naoko Nakano;Kiyosi Yasukawa

  951
  Citations

• CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130

  Nancy Yuk-Yu Ip;Steven H. Nye;Tert G. Boulton;Samuel Davis

  826
  Citations

• Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

  Masaaki Murakami;Masashi Narazaki;Masahiko Hibi;Hideo Yawata

  780
  Citations

• Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene.

  K. Yasukawa;T. Hirano;Y. Watanabe;K. Muratani

  619
  Citations

• A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

  D Guschin;N Rogers;J Briscoe;B Witthuhn

  567
  Citations

• Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130

  Masashi Narazaki;Kiyoshi Yasukawa;Takashi Saito;Yoshiyuki Ohsugi

  537
  Citations

• Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production

  T. Hirano;T. Taga;K. Yasukawa;K. Nakajima

  462
  Citations

• Human soluble IL-6 receptor: its detection and enhanced release by HIV infection.

  M Honda;S Yamamoto;M Cheng;K Yasukawa

  446
  Citations

• Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor

  Takahiro Ueda;Kohichiro Tsuji;Hiroshi Yoshino;Yasuhiro Ebihara

  409
  Citations

• Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.

  Masashi Narazaki;Bruce A. Witthuhn;Kanji Yoshida;Olli Silvennoinen

  394
  Citations

• Involvement of IL-6 signal transducer gp130 in IL-11-mediated signal transduction.

  Tinggui Yin;Tetsuya Taga;Monica Lik Shing Tsang;Kiyoshi Yasukawa

  342
  Citations

• High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130.

  L.D. Ward;G.J. Howlett;G. Discolo;K. Yasukawa

  330
  Citations

• Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways

  Kanji Yoshida;Ian Chambers;Jennifer Nichols;Austin Smith

  286
  Citations

• Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130.

  H Yawata;K Yasukawa;S Natsuka;M Murakami

  271
  Citations

• Increased and highly stable levels of functional soluble interleukin‐6 receptor in sera of patients with monoclonal gammopathy

  Jean-Philippe Gaillard;Régis Bataille;Hervé Brailly;Caroline Zuber

  254
  Citations

• Analysis of interleukin 6 receptor and gp130 expressions and proliferative capability of human CD34+ cells.

  S Tajima;K Tsuji;Y Ebihara;X Sui

  166
  Citations