D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 43 Citations 7,486 87 World Ranking 16709 National Ranking 6898

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Signal transduction

Cell biology, Molecular biology, Heterotrimeric G protein, Signal transduction and Complementary DNA are his primary areas of study. His Molecular biology study integrates concerns from other disciplines, such as Integrin, beta 6, Integrin alpha M, CD49c, Integrin and RHOA. He is researching Heterotrimeric G protein as part of the investigation of G protein and Biochemistry.

His research in G protein intersects with topics in Biophysics, Guanosine triphosphate, Transmembrane protein and Phosphoinositide phospholipase C, Phospholipase C. His Signal transduction study combines topics from a wide range of disciplines, such as Cell, Schizosaccharomyces pombe and Cyclase activity, Adenylate kinase. Tohru Kozasa combines subjects such as Nucleic acid sequence, Peptide sequence and G alpha subunit with his study of Complementary DNA.

His most cited work include:

  • Structure and Function of Signal-Transducing GTP-Binding Proteins (555 citations)
  • Isolation and characterization of the human Gs alpha gene. (327 citations)
  • Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain. (288 citations)

What are the main themes of his work throughout his whole career to date?

Tohru Kozasa mainly focuses on Cell biology, G protein, Heterotrimeric G protein, Biochemistry and Molecular biology. Signal transduction, Guanine nucleotide exchange factor, GTPase-activating protein, RHOA and Regulator of G protein signaling are the primary areas of interest in his Cell biology study. His Signal transduction research incorporates elements of PDZ domain and Effector.

Tohru Kozasa has included themes like Patch clamp, Biophysics, Protein subunit and G protein-coupled receptor in his G protein study. Alternative splicing and Exon is closely connected to G alpha subunit in his research, which is encompassed under the umbrella topic of Heterotrimeric G protein. His Molecular biology study incorporates themes from Complementary DNA, Peptide sequence, Gene and Alpha.

He most often published in these fields:

  • Cell biology (67.03%)
  • G protein (53.85%)
  • Heterotrimeric G protein (40.66%)

What were the highlights of his more recent work (between 2010-2018)?

  • Cell biology (67.03%)
  • Heterotrimeric G protein (40.66%)
  • G protein (53.85%)

In recent papers he was focusing on the following fields of study:

Tohru Kozasa mostly deals with Cell biology, Heterotrimeric G protein, G protein, Regulator of G protein signaling and Biochemistry. Guanine nucleotide exchange factor, RHOA, Phosphorylation, Signal transduction and Kinase are among the areas of Cell biology where Tohru Kozasa concentrates his study. Tohru Kozasa works in the field of Heterotrimeric G protein, focusing on GTP-Binding Protein alpha Subunits in particular.

His G protein research incorporates themes from Secretion and Basal. The Basal study combines topics in areas such as Molecular biology, Neuroscience and Thrombin. His research in Biochemistry is mostly focused on Protein structure.

Between 2010 and 2018, his most popular works were:

  • PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12. (97 citations)
  • PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12. (97 citations)
  • Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13. (46 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Signal transduction

His primary areas of study are Cell biology, Heterotrimeric G protein, Kinase, GTP-Binding Protein alpha Subunits and Signal transduction. His Cell biology study frequently links to other fields, such as Protein structure. Tohru Kozasa combines subjects such as RGS2, G beta-gamma complex, GTPase-activating protein and Regulator of G protein signaling with his study of Protein structure.

Tohru Kozasa is interested in Guanine nucleotide exchange factor, which is a branch of Signal transduction. As a part of the same scientific study, Tohru Kozasa usually deals with the Protein kinase B, concentrating on Fibroblast migration and frequently concerns with ARAF. Tohru Kozasa interconnects Cell signaling, Cell growth and G alpha subunit in the investigation of issues within G protein.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure and Function of Signal-Transducing GTP-Binding Proteins

Yoshito Kaziro;Hiroshi Itoh;Tohru Kozasa;Masato Nakafuku.
Annual Review of Biochemistry (1991)

856 Citations

Isolation and characterization of the human Gs alpha gene.

Tohru Kozasa;Hiroshi Itoh;Toshihiko Tsukamoto;Yoshito Kaziro.
Proceedings of the National Academy of Sciences of the United States of America (1988)

506 Citations

Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

H. Itoh;T. Kozasa;S. Nagata;S. Nakamura.
Proceedings of the National Academy of Sciences of the United States of America (1986)

435 Citations

Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex.

Valerie M. Tesmer;Takeharu Kawano;Aruna Shankaranarayanan;Aruna Shankaranarayanan;Tohru Kozasa.
Science (2005)

363 Citations

Presence of Three Distinct Molecular Species of Gi Protein Alpha Subunit. Structure of Rat cDNAs and Human Genomic DNAs

H Itoh;R Toyama;T Kozasa;T Tsukamoto.
Journal of Biological Chemistry (1988)

355 Citations

Role of a ras homolog in the life cycle of Schizosaccharomyces pombe.

Yasuhisa Fukui;Tohru Kozasa;Yoshito Kaziro;Tadayukl Takeda.
Cell (1986)

331 Citations

Gα12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF

Nobuchika Suzuki;Susumu Nakamura;Hiroyuki Mano;Tohru Kozasa.
Proceedings of the National Academy of Sciences of the United States of America (2003)

279 Citations

Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit.

Masaaki Matsuoka;Hiroshi Itoh;Tohru Kozasa;Yoshito Kaziro.
Proceedings of the National Academy of Sciences of the United States of America (1988)

275 Citations

Kinetic Scaffolding Mediated by a Phospholipase C–β and Gq Signaling Complex

Gary L. Waldo;Tiffany K. Ricks;Stephanie N. Hicks;Matthew L. Cheever.
Science (2010)

244 Citations

G protein subunit Gα13 binds to integrin αIIbβ3 and mediates integrin “outside-in” signaling

Haixia Gong;Bo Shen;Panagiotis Flevaris;Christina Chow.
Science (2010)

242 Citations

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