World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
15168
World Ranking
11247
National Ranking
4869

Overview

Tohru Kozasa is affiliated with the University of Illinois at Chicago in the United States. Their research spans several scientific disciplines, primarily focusing on Agricultural and Biological Sciences, Medicine, and Biochemistry, Genetics, and Molecular Biology. The work involves interconnected subfields including Insect Science, Food Science, Oncology, Molecular Biology, and Cancer Research.

The main research topics covered by Kozasa include Bee Products Chemical Analysis, Essential Oils and Antimicrobial Activity, Insect and Pesticide Research, Cancer-related Molecular Pathways, Protein Kinase Regulation and GTPase Signaling, Protease and Inhibitor Mechanisms, and Cell Adhesion Molecules Research.

Kozasa has contributed to multiple research papers published in various venues. Notable publications include:

  • Effect of manuka honey on human immunodeficiency virus type 1 reverse transcriptase activity, 2021, Natural Product Research
  • Gα q Directly Activates p63RhoGEF and Trio via a Conserved Extension of the Dbl Homology-associated Pleckstrin Homology Domain, 2020, UNC Libraries
  • Receptor-independent regulation of Gα13 by alpha-1-antitrypsin C-terminal peptides, 2024, Journal of Biological Chemistry

Frequent collaborators in their research include Etienne Kochole Obossou, Yasuo Shikamoto, Yuki Hoshino, Hayato Kohno, and Yukiko Ishibasi. Collaborative efforts cover diverse topics and demonstrate cross-disciplinary connections.

Kozasa's publications have appeared in several scientific venues, with contributions noted in Natural Product Research, UNC Libraries, and the Journal of Biological Chemistry. These venues reflect the scientist's engagement with both specialized and interdisciplinary research communities.

Best Publications

  • p115 RhoGEF, a GTPase activating protein for Gα12 and Gα13

    Tohru Kozasa;Xuejun Jiang;Matthew J. Hart;Pamela M. Sternweis

  • Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα13

    Matthew J. Hart;Xuejun Jiang;Tohru Kozasa;William Roscoe

  • Structure and Function of Signal-Transducing GTP-Binding Proteins

    Yoshito Kaziro;Hiroshi Itoh;Tohru Kozasa;Masato Nakafuku

  • Isolation and characterization of the human Gs alpha gene.

    Tohru Kozasa;Hiroshi Itoh;Toshihiko Tsukamoto;Yoshito Kaziro

  • The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis.

    David M. Berman;Tohru Kozasa;Alfred G. Gilman

  • RGS4 and GAIP are GTPase-activating proteins for Gqα and block activation of phospholipase Cβ by γ-thio-GTP-Gqα

    John R. Hepler;David M. Berman;Alfred G. Gilman;Tohru Kozasa

  • Purification of recombinant G proteins from Sf9 cells by hexahistidine tagging of associated subunits. Characterization of alpha 12 and inhibition of adenylyl cyclase by alpha z.

    Tohru Kozasa;Alfred G. Gilman

  • Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

    H. Itoh;T. Kozasa;S. Nagata;S. Nakamura

  • Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2.

    Christopher V. Carman;Jean Luc Parent;Peter W. Day;Alexey N. Pronin

  • Snapshot of Activated G Proteins at the Membrane: The Gαq-GRK2-Gßγ Complex

    Valerie M. Tesmer;Takeharu Kawano;Aruna Shankaranarayanan;Tohru Kozasa

  • Presence of Three Distinct Molecular Species of Gi Protein Alpha Subunit. Structure of Rat cDNAs and Human Genomic DNAs

    H Itoh;R Toyama;T Kozasa;T Tsukamoto

  • Purification from Sf9 cells and characterization of recombinant Gq alpha and G11 alpha. Activation of purified phospholipase C isozymes by G alpha subunits.

    John R. Hepler;Tohru Kozasa;Alan V. Smrcka;Melvin I. Simon

  • Role of a ras homolog in the life cycle of Schizosaccharomyces pombe.

    Yasuhisa Fukui;Tohru Kozasa;Yoshito Kaziro;Tadayukl Takeda

  • Gα12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF

    Nobuchika Suzuki;Susumu Nakamura;Hiroyuki Mano;Tohru Kozasa

  • Kinetic Scaffolding Mediated by a Phospholipase C–β and Gq Signaling Complex

    Gary L. Waldo;Tiffany K. Ricks;Stephanie N. Hicks;Matthew L. Cheever

  • G protein subunit Gα13 binds to integrin αIIbβ3 and mediates integrin “outside-in” signaling

    Haixia Gong;Bo Shen;Panagiotis Flevaris;Christina Chow

  • Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit.

    Masaaki Matsuoka;Hiroshi Itoh;Tohru Kozasa;Yoshito Kaziro

  • Direct stimulation of Bruton's tyrosine kinase by G q -protein α-subunit

    Kendra Bence;Wei Ma;Tohru Kozasa;Xin-Yun Huang

  • The G protein Gα12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain

    Yun Jiang;Wei Ma;Yong Wan;Tohru Kozasa

  • Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation.

    Hyeseon Cho;Tohru Kozasa;Cecilia Bondjers;Christer Betsholtz

Frequent Co-Authors

Yoshito Kaziro
Yoshito Kaziro Kyoto University
Takao Hamakubo
Takao Hamakubo Nippon Medical School
John J. G. Tesmer
John J. G. Tesmer Purdue University West Lafayette
Motohiro Nishida
Motohiro Nishida Kyushu University
Tatsuhiko Kodama
Tatsuhiko Kodama University of Tokyo
Hitoshi Kurose
Hitoshi Kurose University of Tokushima
Richard R. Neubig
Richard R. Neubig Michigan State University
Xiaoping Du
Xiaoping Du University of Illinois at Chicago
Toshiaki Katada
Toshiaki Katada Musashino University
Richard D. Ye
Richard D. Ye Chinese University of Hong Kong, Shenzhen

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