Hitoshi Kurose

Overview

Best Publications

• LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death

  Yuji Hara;Minoru Wakamori;Masakazu Ishii;Emi Maeno;Emi Maeno

  981
  Citations

• Specific uncoupling by islet-activating protein, pertussis toxin, of negative signal transduction via alpha-adrenergic, cholinergic, and opiate receptors in neuroblastoma x glioma hybrid cells.

  H Kurose;T Katada;T Amano;M Ui

  697
  Citations

• TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.

  Naoya Onohara;Motohiro Nishida;Ryuji Inoue;Hiroyuki Kobayashi

  461
  Citations

• Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs.

  M G Eason;H Kurose;B D Holt;J R Raymond

  441
  Citations

• Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound

  Shigeki Kiyonaka;Kenta Kato;Motohiro Nishida;Kazuhiro Mio

  417
  Citations

• Constitutively active mutants of the alpha 2-adrenergic receptor.

  Quen Ren;Hitoshi Kurose;Robert J. Lefkowitz;Susanna Cotecchia

  350
  Citations

• Gα i and Gα o are target proteins of reactive oxygen species

  Motohiro Nishida;Yoshiko Maruyama;Rie Tanaka;Kenji Kontani

  339
  Citations

• Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration

  Motohiro Nishida;Tomohiro Sawa;Naoyuki Kitajima;Katsuhiko Ono

  326
  Citations

• TDAG8 Is a Proton-sensing and Psychosine-sensitive G-protein-coupled Receptor

  Ju-Qiang Wang;Junko Kon;Chihiro Mogi;Masayuki Tobo

  291
  Citations

• Gi/o Protein-Dependent and -Independent Actions of Pertussis Toxin (PTX)

  Supachoke Mangmool;Hitoshi Kurose

  257
  Citations

• P2Y6 receptor-Gα12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis

  Motohiro Nishida;Yoji Sato;Aya Uemura;Yusuke Narita

  238
  Citations

• Participation of adenosine 5′-triphosphate in the activation of membrane-bound guanylate cyclase by the atrial natriuretic factor

  Hitoshi Kurose;Tadashi Inagami;Michio Ui

  223
  Citations

• Functional interaction of purified muscarinic receptors with purified inhibitory guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles.

  H Kurose;T Katada;T Haga;K Haga

  221
  Citations

• Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2.

  H Tsuga;K Kameyama;T Haga;H Kurose

  204
  Citations

• Gα12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes

  Motohiro Nishida;Shihori Tanabe;Yoshiko Maruyama;Supachoke Mangmool

  201
  Citations

• Cellular and subcellular sites for noradrenergic action in the monkey dorsolateral prefrontal cortex as revealed by the immunocytochemical localization of noradrenergic receptors and axons.

  Chiye Aoki;Charu Venkatesan;C. G. Go;Robin Forman

  195
  Citations

• Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism.

  S B Liggett;J Ostrowski;L C Chesnut;H Kurose

  177
  Citations

• Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart

  Hideyuki Kinoshita;Koichiro Kuwahara;Motohiro Nishida;Zhong Jian;Zhong Jian

  174
  Citations

• Gα12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation

  Motohiro Nishida;Naoya Onohara;Yoji Sato;Reiko Suda

  174
  Citations

• Gα12 and Gα13 as key regulatory mediator in signal transduction

  Hitoshi Kurose

  165
  Citations