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Kazuhide Inoue

Kazuhide Inoue

D-Index & Metrics

Neuroscience

D-Index
93
Citations
32239
World Ranking
988
National Ranking
15

Biology and Biochemistry

D-Index
93
Citations
32217
World Ranking
2102
National Ranking
120

Overview

Kazuhide Inoue is affiliated with Kyushu University in Japan and focuses their research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans subfields including Physiology, Molecular Biology, Cellular and Molecular Neuroscience, Cardiology and Cardiovascular Medicine, and Neurology.

The scientist's research topics prominently feature Pain Mechanisms and Treatments, Adenosine and Purinergic Signaling, Neuropeptides and Animal Physiology, Pharmacological Receptor Mechanisms and Effects, Nerve Injury and Regeneration, Neuroinflammation and Neurodegeneration Mechanisms, and Ion Channel Regulation and Function.

Recent papers authored or co-authored by Kazuhide Inoue include:

  • "A spinal microglia population involved in remitting and relapsing neuropathic pain," 2022, Science
  • "Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity," 2020, Nature Neuroscience
  • "Nociceptive signaling mediated by P2X3, P2X4 and P2X7 receptors," 2020, Biochemical Pharmacology
  • "Astrocytic STAT3 activation and chronic itch require IP3R1/TRPC-dependent Ca2+ signals in mice," 2020, Journal of Allergy and Clinical Immunology
  • "Nociceptive signaling of P2X receptors in chronic pain states," 2020, Purinergic Signalling

Collaborators frequently working with Kazuhide Inoue include Makoto Tsuda, Keita Kohno, Hidetoshi Tozaki-Saitoh, Kohei Yoshihara, and Haruhiko Higashi.

Publication venues where Kazuhide Inoue has contributed multiple works include Proceedings for Annual Meeting of The Japanese Pharmacological Society, Scientific Reports, In Vivo, Science, and Nature Neuroscience.

Best Publications

  • BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

    Jeffrey A. M. Coull;Simon Beggs;Dominic Boudreau;Dominick Boivin

  • P2x4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

    Makoto Tsuda;Yukari Shigemoto-Mogami;Schuichi Koizumi;Akito Mizokoshi

  • Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia.

    Makoto Tsuda;Kazuhide Inoue;Michael W. Salter

  • UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

    Schuichi Koizumi;Yukari Shigemoto-Mogami;Kaoru Nasu-Tada;Yoichi Shinozaki

  • Neuronal ‘On’ and ‘Off’ signals control microglia

    Knut Biber;Harald Neumann;Kazuhide Inoue;Hendrikus W.G.M. Boddeke

  • Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors.

    Shizuyo Honda;Yo Sasaki;Keiko Ohsawa;Yoshinori Imai

  • Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential

    Kazuhide Inoue;Makoto Tsuda

  • Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury.

    Makoto Tsuda;Akito Mizokoshi;Yukari Shigemoto-Mogami;Schuichi Koizumi

  • Production and Release of Neuroprotective Tumor Necrosis Factor by P2X7 Receptor-Activated Microglia

    Tomohisa Suzuki;Izumi Hide;Katsutoshi Ido;Shinichi Kohsaka

  • Extracellular ATP Triggers Tumor Necrosis Factor-α Release from Rat Microglia

    Izumi Hide;Masaya Tanaka;Atsuko Inoue;Kazuyuki Nakajima

  • The function of microglia through purinergic receptors: neuropathic pain and cytokine release.

    Kazuhide Inoue

  • Microglial activation by purines and pyrimidines

    Kazuhide Inoue

  • Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes.

    M. Nakajima;T. Yamamoto;K.-I. Nunoya;T. Yokoi

  • Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis.

    Keiko Ohsawa;Yasuhiro Irino;Yasuko Nakamura;Chihiro Akazawa

  • IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

    Takahiro Masuda;Makoto Tsuda;Ryohei Yoshinaga;Hidetoshi Tozaki-Saitoh

  • Microglia and neuropathic pain.

    Kazuhide Inoue;Makoto Tsuda

  • Functional vanilloid receptors in cultured normal human epidermal keratinocytes

    Kaori Inoue;Schuichi Koizumi;Shigeyoshi Fuziwara;Sumiko Denda

  • JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats

    Makoto Tsuda;Yuta Kohro;Takayuki Yano;Tomoko Tsujikawa

  • Possible Involvement of P2Y2 Metabotropic Receptors in ATP-Induced Transient Receptor Potential Vanilloid Receptor 1-Mediated Thermal Hypersensitivity

    Tomoko Moriyama;Tohko Iida;Kimiko Kobayashi;Tomohiro Higashi

  • P2Y12 Receptors in Spinal Microglia Are Required for Neuropathic Pain after Peripheral Nerve Injury

    Hidetoshi Tozaki-Saitoh;Makoto Tsuda;Hiroyuki Miyata;Kazuaki Ueda

  • Microglial α7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role

    Tomohisa Suzuki;Izumi Hide;Akiyo Matsubara;Chihiro Hama

Frequent Co-Authors

Makoto Tsuda
Makoto Tsuda Kyushu University
Schuichi Koizumi
Schuichi Koizumi University of Yamanashi
Hidetoshi Tozaki-Saitoh
Hidetoshi Tozaki-Saitoh Kyushu University
Shinichi Kohsaka
Shinichi Kohsaka Keio University
Koichi Shudo
Koichi Shudo University of Tokyo
Jun-ichi Sawada
Jun-ichi Sawada University of Shizuoka
Michael W. Salter
Michael W. Salter University of Toronto
Tomohiko Tamura
Tomohiko Tamura Yokohama City University
Hiroshi Nakanishi
Hiroshi Nakanishi Yasuda Women's University
Hidemasa Furue
Hidemasa Furue Hyogo College of Medicine

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