Makoto Tsuda

Overview

Best Publications

• BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

  Jeffrey A. M. Coull;Simon Beggs;Dominic Boudreau;Dominick Boivin

  2234
  Citations

• P2x4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

  Makoto Tsuda;Yukari Shigemoto-Mogami;Schuichi Koizumi;Akito Mizokoshi

  1837
  Citations

• Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia.

  Makoto Tsuda;Kazuhide Inoue;Michael W. Salter

  996
  Citations

• UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

  Schuichi Koizumi;Yukari Shigemoto-Mogami;Kaoru Nasu-Tada;Yoichi Shinozaki

  929
  Citations

• Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential

  Kazuhide Inoue;Makoto Tsuda

  817
  Citations

• Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury.

  Makoto Tsuda;Akito Mizokoshi;Yukari Shigemoto-Mogami;Schuichi Koizumi

  605
  Citations

• Specification of CNS macrophage subsets occurs postnatally in defined niches

  Unknown

  367
  Citations

• IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

  Takahiro Masuda;Makoto Tsuda;Ryohei Yoshinaga;Hidetoshi Tozaki-Saitoh

  352
  Citations

• Microglia and neuropathic pain.

  Kazuhide Inoue;Makoto Tsuda

  344
  Citations

• JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats

  Makoto Tsuda;Yuta Kohro;Takayuki Yano;Tomoko Tsujikawa

  338
  Citations

• P2Y12 Receptors in Spinal Microglia Are Required for Neuropathic Pain after Peripheral Nerve Injury

  Hidetoshi Tozaki-Saitoh;Makoto Tsuda;Hiroyuki Miyata;Kazuaki Ueda

  334
  Citations

• IFN-γ receptor signaling mediates spinal microglia activation driving neuropathic pain

  Makoto Tsuda;Takahiro Masuda;Junko Kitano;Hiroshi Shimoyama

  305
  Citations

• Dynamic inhibition of excitatory synaptic transmission by astrocyte-derived ATP in hippocampal cultures.

  Schuichi Koizumi;Kayoko Fujishita;Makoto Tsuda;Yukari Shigemoto-Mogami

  301
  Citations

• A spinal microglia population involved in remitting and relapsing neuropathic pain

  Unknown

  290
  Citations

• Mechanical Allodynia Caused by Intraplantar Injection of P2X Receptor Agonist in Rats: Involvement of Heteromeric P2X2/3 Receptor Signaling in Capsaicin-Insensitive Primary Afferent Neurons

  Makoto Tsuda;Schuichi Koizumi;Aya Kita;Yukari Shigemoto

  272
  Citations

• Microglia in the spinal cord and neuropathic pain

  Makoto Tsuda

  268
  Citations

• Ca2+ waves in keratinocytes are transmitted to sensory neurons: the involvement of extracellular ATP and P2Y2 receptor activation.

  Schuichi Koizumi;Kayoko Fujishita;Kaori Inoue;Yukari Shigemoto-Mogami

  265
  Citations

• The liver-brain-gut neural arc maintains the Treg cell niche in the gut.

  Toshiaki Teratani;Yohei Mikami;Nobuhiro Nakamoto;Takahiro Suzuki

  254
  Citations

• STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch

  Miho Shiratori-Hayashi;Keisuke Koga;Hidetoshi Tozaki-Saitoh;Yuta Kohro

  251
  Citations

• Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic pain.

  Takahiro Masuda;Shosuke Iwamoto;Ryohei Yoshinaga;Hidetoshi Tozaki-Saitoh

  245
  Citations

• Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays

  Makoto Tsuda;Kazuya Kuboyama;Tomoyuki Inoue;Kenichiro Nagata

  240
  Citations

• Cell type‐specific ATP‐activated responses in rat dorsal root ganglion neurons

  Shinya Ueno;Makoto Tsuda;Toshihiko Iwanaga;Kazuhide Inoue

  213
  Citations

• Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5

  Yukari Shigemoto-Mogami;Schuichi Koizumi;Makoto Tsuda;Keiko Ohsawa

  209
  Citations