D-Index & Metrics Best Publications
Neuroscience
Japan
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 65 Citations 16,794 224 World Ranking 1797 National Ranking 46

Research.com Recognitions

Awards & Achievements

2023 - Research.com Neuroscience in Japan Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Neuron

Makoto Tsuda focuses on Neuroscience, Neuropathic pain, Nerve injury, Microglia and Peripheral nerve injury. The concepts of his Neuroscience study are interwoven with issues in Hyperalgesia and PPADS. His studies in Neuropathic pain integrate themes in fields like Purinergic receptor and Chronic pain.

His research in Nerve injury intersects with topics in Spinal nerve, Spinal cord and Allodynia. His Microglia research incorporates themes from Neuroglia, MAPK/ERK pathway and Cell biology. By researching both Peripheral nerve injury and Nervous system, he produces research that crosses academic boundaries.

His most cited work include:

  • BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain (1412 citations)
  • P2x4 receptors induced in spinal microglia gate tactile allodynia after nerve injury (1187 citations)
  • Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia. (651 citations)

What are the main themes of his work throughout his whole career to date?

Neuroscience, Neuropathic pain, Microglia, Receptor and Pharmacology are his primary areas of study. His biological study spans a wide range of topics, including Dorsum and Nociception. His Neuropathic pain research includes elements of Nerve injury, Chronic pain and Allodynia.

His Microglia research is multidisciplinary, relying on both Purinergic receptor, Downregulation and upregulation, IRF8 and Cell biology. His Receptor study integrates concerns from other disciplines, such as Extracellular, Molecular biology and Dorsal root ganglion. His Pharmacology study combines topics in areas such as NMDA receptor, Antagonist and Agonist.

He most often published in these fields:

  • Neuroscience (43.93%)
  • Neuropathic pain (33.89%)
  • Microglia (33.89%)

What were the highlights of his more recent work (between 2018-2021)?

  • Neuroscience (43.93%)
  • Spinal cord (15.48%)
  • Microglia (33.89%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Neuroscience, Spinal cord, Microglia, Neuropathic pain and Receptor. Makoto Tsuda has included themes like Dorsum and Noxious stimulus in his Neuroscience study. His Spinal cord research incorporates elements of Interleukin 6, STAT3, Chronic pain and Glial fibrillary acidic protein.

His Microglia research is multidisciplinary, incorporating perspectives in Proinflammatory cytokine, Recovery phase and Cell type. He combines subjects such as Nerve injury and Allodynia with his study of Neuropathic pain. His Receptor research integrates issues from Molecular biology, Gut flora, Monoclonal antibody and Cell biology.

Between 2018 and 2021, his most popular works were:

  • Transcription factor MafB contributes to the activation of spinal microglia underlying neuropathic pain development (20 citations)
  • The liver-brain-gut neural arc maintains the Treg cell niche in the gut. (19 citations)
  • Microglia-Mediated Regulation of Neuropathic Pain: Molecular and Cellular Mechanisms. (13 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Neuron

Makoto Tsuda spends much of his time researching Neuroscience, Spinal cord, Central nervous system, Microglia and Receptor. His study in the fields of Brainstem and Reflex arc under the domain of Neuroscience overlaps with other disciplines such as Gastrin-releasing peptide and Adeno-associated virus. Makoto Tsuda interconnects Internal medicine, Chronic stress and Chronic pain in the investigation of issues within Spinal cord.

His work deals with themes such as Purinergic receptor, Muscarinic acetylcholine receptor, Gut flora and Homeostasis, which intersect with Central nervous system. He undertakes multidisciplinary studies into Microglia and Peripheral nerve injury in his work. The various areas that he examines in his Receptor study include STAT3 and Antibody.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

Jeffrey A. M. Coull;Simon Beggs;Dominic Boudreau;Dominick Boivin.
Nature (2005)

1996 Citations

P2x4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

Makoto Tsuda;Yukari Shigemoto-Mogami;Schuichi Koizumi;Akito Mizokoshi.
Nature (2003)

1665 Citations

Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia.

Makoto Tsuda;Kazuhide Inoue;Michael W. Salter.
Trends in Neurosciences (2005)

943 Citations

UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

Schuichi Koizumi;Yukari Shigemoto-Mogami;Kaoru Nasu-Tada;Yoichi Shinozaki.
Nature (2007)

788 Citations

Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury.

Makoto Tsuda;Akito Mizokoshi;Yukari Shigemoto-Mogami;Schuichi Koizumi.
Glia (2004)

560 Citations

Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential

Kazuhide Inoue;Makoto Tsuda.
Nature Reviews Neuroscience (2018)

366 Citations

Microglia and neuropathic pain.

Kazuhide Inoue;Makoto Tsuda.
Glia (2009)

307 Citations

P2Y12 Receptors in Spinal Microglia Are Required for Neuropathic Pain after Peripheral Nerve Injury

Hidetoshi Tozaki-Saitoh;Makoto Tsuda;Hiroyuki Miyata;Kazuaki Ueda.
The Journal of Neuroscience (2008)

294 Citations

Dynamic inhibition of excitatory synaptic transmission by astrocyte-derived ATP in hippocampal cultures.

Schuichi Koizumi;Kayoko Fujishita;Makoto Tsuda;Yukari Shigemoto-Mogami.
Proceedings of the National Academy of Sciences of the United States of America (2003)

283 Citations

Mechanical Allodynia Caused by Intraplantar Injection of P2X Receptor Agonist in Rats: Involvement of Heteromeric P2X2/3 Receptor Signaling in Capsaicin-Insensitive Primary Afferent Neurons

Makoto Tsuda;Schuichi Koizumi;Aya Kita;Yukari Shigemoto.
The Journal of Neuroscience (2000)

264 Citations

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