D-Index & Metrics Best Publications
Research.com 2022 Best Female Scientist Award Badge

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 97 Citations 31,876 261 World Ranking 478 National Ranking 278
Best female scientists D-index 116 Citations 41,716 408 World Ranking 397 National Ranking 246

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Female Scientist Award

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Transcription factor

Keiko Ozato mostly deals with Molecular biology, Transcription factor, Cell biology, Interferon regulatory factors and Transcription. Her Molecular biology research incorporates elements of Bromodomain, Antigen, Chromatin, RNA polymerase II and Monoclonal antibody. Keiko Ozato combines subjects such as Interferon, Chromatin immunoprecipitation and Cellular differentiation with her study of Transcription factor.

Keiko Ozato has researched Cell biology in several fields, including Cell growth, Coactivator, RNA, Immunology and Histone. Her work carried out in the field of Immunology brings together such families of science as Haematopoiesis and Gene expression. Keiko Ozato interconnects Interleukin 12, Signal transduction, Regulatory sequence and RANK Ligand in the investigation of issues within Interferon regulatory factors.

Her most cited work include:

  • The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. (906 citations)
  • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. (851 citations)
  • A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. (845 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include Molecular biology, Cell biology, Transcription factor, IRF8 and Immunology. Her Molecular biology research is multidisciplinary, incorporating elements of Transcription, Gene expression, Gene, Antigen and Antibody. Keiko Ozato has included themes like Retinoid X receptor and RNA polymerase II in her Transcription study.

Her Cell biology research incorporates themes from Cellular differentiation, Interferon, Dendritic cell, Histone and Regulation of gene expression. Bromodomain is closely connected to Chromatin in her research, which is encompassed under the umbrella topic of Transcription factor. Her research integrates issues of Haematopoiesis, Myeloid, Cancer research, Progenitor cell and Monocyte in her study of IRF8.

She most often published in these fields:

  • Molecular biology (46.15%)
  • Cell biology (31.97%)
  • Transcription factor (24.28%)

What were the highlights of her more recent work (between 2011-2021)?

  • Cell biology (31.97%)
  • IRF8 (18.51%)
  • Transcription factor (24.28%)

In recent papers she was focusing on the following fields of study:

Keiko Ozato focuses on Cell biology, IRF8, Transcription factor, Immunology and Molecular biology. Her Cell biology research is multidisciplinary, incorporating perspectives in Chromatin, Histone, Epigenetics and Myeloid. The concepts of her IRF8 study are interwoven with issues in Haematopoiesis, Cellular differentiation, Monocyte, Progenitor cell and Interferon regulatory factors.

Her Interferon regulatory factors study which covers Microglia that intersects with Gene expression and Cancer research. Her studies in Transcription factor integrate themes in fields like Regulation of gene expression, Dendritic cell, Bone marrow and Transcriptome. Her Molecular biology study combines topics from a wide range of disciplines, such as Transcription factor II B, Chromatin immunoprecipitation, General transcription factor, Promoter and Glucocorticoid receptor.

Between 2011 and 2021, her most popular works were:

  • Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. (267 citations)
  • BRD4 is an atypical kinase that phosphorylates Serine2 of the RNA Polymerase II carboxy-terminal domain (256 citations)
  • IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype (182 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Transcription factor

Keiko Ozato spends much of her time researching IRF8, Cell biology, Transcription factor, Molecular biology and Cellular differentiation. Her study in IRF8 is interdisciplinary in nature, drawing from both Myeloid, Cancer research, Immunology, Microglia and Interferon regulatory factors. Her Cell biology research includes elements of CD28, Cytotoxic T cell, ZAP70 and Antigen-presenting cell.

Her Transcription factor study incorporates themes from SENP1, Regulation of gene expression and Transcription. The study incorporates disciplines such as Transcription coregulator, Chromatin remodeling, Histone acetyltransferase, Nucleosome and Histone methylation in addition to Molecular biology. The Cellular differentiation study combines topics in areas such as Enhancer, T cell, Haematopoiesis and Monocyte.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.

Moon Kyoo Jang;Kazuki Mochizuki;Meisheng Zhou;Ho-Sang Jeong.
Molecular Cell (2005)

1355 Citations

Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens.

K Ozato;N Mayer;D H Sachs.
Journal of Immunology (1980)

1094 Citations

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo.

Mitchell H. Rosner;Mitchell H. Rosner;M. Alessandra Vigano;Keiko Ozato;Paula M. Timmons.
Nature (1990)

1093 Citations

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

Hansjorg Keller;Christine Dreyer;Jeffrey Medin;Abderrahim Mahfoudi.
Proceedings of the National Academy of Sciences of the United States of America (1993)

1085 Citations

Recruitment of P-TEFb for Stimulation of Transcriptional Elongation by the Bromodomain Protein Brd4

Zhiyuan Yang;Jasper H.N. Yik;Ruichuan Chen;Ruichuan Chen;Nanhai He.
Molecular Cell (2005)

976 Citations

TRIM family proteins and their emerging roles in innate immunity

Keiko Ozato;Dong-Mi Shin;Tsung-Hsien Chang;Herbert C. Morse.
Nature Reviews Immunology (2008)

848 Citations

Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression.

K Ozato;D H Sachs.
Journal of Immunology (1981)

760 Citations

Immunodeficiency and Chronic Myelogenous Leukemia-like Syndrome in Mice with a Targeted Mutation of the ICSBP Gene

Thomas Holtschke;Jürgen Löhler;Yuka Kanno;Thomas Fehr.
Cell (1996)

671 Citations

The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

Anup Dey;Farideh Chitsaz;Asim Abbasi;Tom Misteli.
Proceedings of the National Academy of Sciences of the United States of America (2003)

602 Citations

Monoclonal antibodies to mouse major histocompatibility complex antigens.

Keiko Ozato;Nanci M. Mayer;David H. Sachs.
Transplantation (1982)

590 Citations

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