World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
9800
World Ranking
14014
National Ranking
5913

Overview

Mitchell Ho is affiliated with the Center for Cancer Research in the United States and has a robust publication record in the fields of medicine, biochemistry, genetics, and molecular biology. Their research primarily focuses on oncology, immunology, and related biomedical disciplines.

The scientist's major areas of study include:

  • Oncology
  • Immunology
  • Radiology, Nuclear Medicine and Imaging
  • Molecular Biology
  • Infectious Diseases

Mitchell Ho's work spans several key research topics, notably in immune-based therapies and molecular mechanisms in cancer and infectious diseases. Their main topics of interest include:

  • CAR-T cell therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • Immunotherapy and Immune Responses
  • Glycosylation and Glycoproteins Research
  • SARS-CoV-2 and COVID-19 Research
  • Neuroblastoma Research and Treatments
  • Immune Cell Function and Interaction

Mitchell Ho has authored multiple research articles, contributing to the scientific discourse on cancer and immunotherapy. Representative recent publications include:

  • Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice, 2020, Gastroenterology
  • Cancer therapy with antibodies, 2024, Nature reviews. Cancer
  • COVID-19 antibody therapeutics tracker: a global online database of antibody therapeutics for the prevention and treatment of COVID-19, 2020, Antibody Therapeutics
  • Shed antigen-induced blocking effect on CAR-T cells targeting Glypican-3 in Hepatocellular Carcinoma, 2021, Journal for ImmunoTherapy of Cancer
  • The Role of Glypicans in Cancer Progression and Therapy, 2020, Journal of Histochemistry & Cytochemistry

The scientist frequently collaborates with a core group of researchers, enhancing interdisciplinary engagement. Frequent co-authors include:

  • Dan Li
  • Nan Li
  • Jessica Hong
  • Zhijian Duan
  • T. Jake Liang

Mitchell Ho's publications are often featured in specialized venues related to antibody therapeutics and cancer research. Key publication venues consist of:

  • Antibody Therapeutics
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal for ImmunoTherapy of Cancer
  • Nature Communications

Best Publications

  • High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

    Yi Chung Tung;Yi Chung Tung;Amy Y. Hsiao;Steven G. Allen;Yu Suke Torisawa

  • Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors

    Jennifer A A Gubbels;Jennifer Belisle;Masanori Onda;Claudine Rancourt

  • Mesothelin targeted cancer immunotherapy.

    Raffit Hassan;Mitchell Ho

  • Glypican-3: a new target for cancer immunotherapy

    Mitchell Ho;Heungnam Kim

  • Role of sorafenib in the treatment of advanced hepatocellular carcinoma: An update.

    Angela Gauthier;Mitchell Ho

  • Isolation of anti-CD22 Fv with high affinity by Fv display on human cells.

    Mitchell Ho;Satoshi Nagata;Ira Pastan

  • A Phase I Clinical Trial of Single-Dose Intrapleural IFN-β Gene Transfer for Malignant Pleural Mesothelioma and Metastatic Pleural Effusions: High Rate of Antitumor Immune Responses

    Daniel H. Sterman;Adri Recio;Richard G. Carroll;Colin T. Gillespie

  • A Binding Domain on Mesothelin for CA125/MUC16

    Osamu Kaneko;Lucy Gong;Jingli Zhang;Johanna K. Hansen

  • Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma

    Mingqian Feng;Wei Gao;Ruoqi Wang;Weizao Chen

  • Humoral Immune Response to Mesothelin in Mesothelioma and Ovarian Cancer Patients

    Mitchell Ho;Raffit Hassan;Jingli Zhang;Qing-cheng Wang

  • Mesothelin Expression in Human Lung Cancer

    Mitchell Ho;Tapan K. Bera;Mark C. Willingham;Masanori Onda

  • Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican‐3 for liver cancer therapy

    Wei Gao;Heungnam Kim;Mingqian Feng;Yen Phung

  • New immunotoxins targeting CD123, a stem cell antigen on acute myeloid leukemia cells

    Xing Du;Mitchell Ho;Ira Pastan

  • The role of mesothelin in tumor progression and targeted therapy

    Zhewei Tang;Min Qian;Mitchell Ho

  • Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis

    Wei Gao;Zhewei Tang;Yi-Fan Zhang;Mingqian Feng

  • In vitro antibody evolution targeting germline hot spots to increase activity of an anti-CD22 immunotoxin.

    Mitchell Ho;Robert J. Kreitman;Masanori Onda;Ira Pastan

  • Glypican-3 antibodies: A new therapeutic target for liver cancer

    Mingqian Feng;Mitchell Ho

  • Glypicans as Cancer Therapeutic Targets

    Nan Li;Wei Gao;Yi-Fan Zhang;Mitchell Ho

  • Megakaryocyte Potentiation Factor Cleaved from Mesothelin Precursor Is a Useful Tumor Marker in the Serum of Patients with Mesothelioma

    Masanori Onda;Satoshi Nagata;Mitchell Ho;Tapan K. Bera

  • Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma

    Nan Li;Haiying Fu;Haiying Fu;Stephen M. Hewitt;Dimiter S. Dimitrov

Frequent Co-Authors

Ira Pastan
Ira Pastan Center for Cancer Research
Dimiter S. Dimitrov
Dimiter S. Dimitrov University of Pittsburgh
Tim F. Greten
Tim F. Greten National Institutes of Health
Peter L. Choyke
Peter L. Choyke National Institutes of Health
Stephen M. Hewitt
Stephen M. Hewitt National Institutes of Health
Robert J. Kreitman
Robert J. Kreitman National Cancer Institute
David J. FitzGerald
David J. FitzGerald MRC Laboratory of Molecular Biology
Shuichi Takayama
Shuichi Takayama Georgia Institute of Technology
Martin F. Flajnik
Martin F. Flajnik University of Maryland, Baltimore
Matthew D. Hall
Matthew D. Hall National Institutes of Health

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