World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
15401
World Ranking
10147
National Ranking
680

Okio Hino publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Okio Hino sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 350 publications — 85th percentile

85% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Okio Hino D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Okio Hino sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 63 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Okio Hino is affiliated with Juntendo University in Japan and has a research focus encompassing medicine and biochemistry, genetics, and molecular biology. Their work has a particular emphasis on subfields such as pulmonary and respiratory medicine, oncology, molecular biology, cancer research, and biotechnology.

The research topics covered by Okio Hino include:

  • Occupational and environmental lung diseases
  • Cancer research and treatments
  • Cancer, hypoxia, and metabolism
  • Tuberous sclerosis complex research
  • Cancer immunotherapy and biomarkers
  • Pleural and pulmonary diseases
  • Medical imaging and pathology studies

Recent publications authored or co-authored by Okio Hino highlight research on cancer and respiratory diseases. These papers include:

  • "Expression status of PD-L1 and B7-H3 in mesothelioma" (2020), published in Pathology International
  • "Possible reversibility between epithelioid and sarcomatoid types of mesothelioma is independent of ERC/mesothelin expression" (2020), published in Respiratory Research
  • "Interstitial chromosomal deletion of the tuberous sclerosis complex 2 locus is a signature for radiation-associated renal tumors in Eker rats" (2020), published in Cancer Science
  • "Tsc2 mutation rather than Tsc1 mutation dominantly causes a social deficit in a mouse model of tuberous sclerosis complex" (2023), published in Human Genomics
  • "Increased RUNX3 expression mediates tumor-promoting ability of human breast cancer-associated fibroblasts" (2023), published in Cancer Medicine

Okio Hino has frequently published in journals such as Cancer Science, Human Genomics, Pathology International, Cancer Medicine, and Respiratory Research.

Their research collaborations include several frequent co-authors, notably Kazunori Kajino, Masaaki Abe, Toshiyuki Kobayashi, Harumi Saeki, and Yataro Daigo.

Best Publications

  • Autophagy-deficient mice develop multiple liver tumors

    Akito Takamura;Masaaki Komatsu;Taichi Hara;Ayako Sakamoto

  • Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling.

    Xinsheng Gao;Yong Zhang;Peter Arrazola;Okio Hino

  • Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

    Yoshihiro Inami;Satoshi Waguri;Ayako N. Sakamoto;Tsuguka Kouno

  • A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer.

    Toshiyuki Kobayashi;Youko Hirayama;Etsuko Kobayashi;Yoshiaki Kubo

  • Renal Carcinogenesis, Hepatic Hemangiomatosis, and Embryonic Lethality Caused by a Germ-Line Tsc2 Mutation in Mice

    Toshiyuki Kobayashi;Osamu Minowa;Junko Kuno;Hiroaki Mitani

  • Allelotype study of primary hepatocellular carcinoma.

    M Fujimori;T Tokino;O Hino;T Kitagawa

  • A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice

    Toshiyuki Kobayashi;Osamu Minowa;Yoshinobu Sugitani;Setsuo Takai

  • A Mutation in the SDHC Gene of Complex II Increases Oxidative Stress, Resulting in Apoptosis and Tumorigenesis

    Takamasa Ishii;Kayo Yasuda;Akira Akatsuka;Okio Hino

  • Expression and replication of hepatitis B virus genome in transgenic mice

    Kimi Araki;Jun-Ichi Miyazaki;Okio Hino;Naohiro Tomita

  • Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex.

    Atsushi Sato;Shinya Kasai;Toshiyuki Kobayashi;Yukio Takamatsu

  • Biphasic Response of Pancreatic β-Cell Mass to Ablation of Tuberous Sclerosis Complex 2 in Mice

    Yutaka Shigeyama;Toshiyuki Kobayashi;Yoshiaki Kido;Naoko Hashimoto

  • Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer

    Okio Hino;Andres J. P. Klein-Szanto;Jerome J. Freed;Joseph R. Testa

  • Hepatitis C Virus Core Protein Interacts with 14-3-3 Protein and Activates the Kinase Raf-1

    Hiroshi Aoki;Junpei Hayashi;Junpei Hayashi;Mitsuhiko Moriyama;Yasuyuki Arakawa

  • Hepatitis B virus integration site in hepatocellular carcinoma at chromosome 17;18 translocation

    Okio Hino;Thomas B. Shows;Charles E. Rogler

  • Hepatitis C virus core protein activates the MAPK/ERK cascade synergistically with tumor promoter TPA, but not with epidermal growth factor or transforming growth factor α

    Junpei Hayashi;Hiroshi Aoki;Hiroshi Aoki;Kazunori Kajino;Mitsuhiko Moriyama

  • Clinical and genetic spectrum of Birt–Hogg–Dubé syndrome patients in whom pneumothorax and/or multiple lung cysts are the presenting feature

    Makiko Kunogi;Masatoshi Kurihara;Takako Shigihara Ikegami;Toshiyuki Kobayashi

  • Identification of a novel protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product.

    Haruo Tsuchiya;Tokuhiro Iseda;Okio Hino

  • Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis.

    Teruhiko Sato;Kuniaki Seyama;Hiroaki Fujii;Hiroshi Maruyama

  • Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein.

    Y Takagi;T Kobayashi;M Shiono;L Wang

  • A germ-line insertion in the Birt–Hogg–Dubé (BHD) gene gives rise to the Nihon rat model of inherited renal cancer

    Kazuo Okimoto;Junko Sakurai;Toshiyuki Kobayashi;Hiroaki Mitani

Frequent Co-Authors

Masahiro Maeda
Masahiro Maeda Osaka University
Ken Ichi Yamamura
Ken Ichi Yamamura Kumamoto University
Masatoshi Kudo
Masatoshi Kudo Kindai University
Tetsuo Noda
Tetsuo Noda Japanese Foundation For Cancer Research
Kenneth H. Buetow
Kenneth H. Buetow Arizona State University
Yataro Daigo
Yataro Daigo Shiga University of Medical Science
Edward Gabrielson
Edward Gabrielson Johns Hopkins University School of Medicine
Hiroyuki Tsuda
Hiroyuki Tsuda Nagoya City University
Joseph R. Testa
Joseph R. Testa Fox Chase Cancer Center
Shin-Ichi Aizawa
Shin-Ichi Aizawa Prefectural University of Hiroshima

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