D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 108 Citations 42,433 365 World Ranking 3528 National Ranking 1994
Molecular Biology D-index 108 Citations 43,031 364 World Ranking 226 National Ranking 139

Research.com Recognitions

Awards & Achievements

2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary scientific interests are in Cancer research, Carcinogenesis, Molecular biology, Protein kinase B and Gene. The concepts of his Cancer research study are interwoven with issues in Immunohistochemistry, Ovarian cancer, Tumor suppressor gene, Cell cycle and PTEN. His Carcinogenesis research integrates issues from Mesothelioma, Pathology, Oncogene and Immunology.

His biological study spans a wide range of topics, including Nucleic acid sequence, Gene expression, Coding region, Subfamily and AKT2. His Protein kinase B study integrates concerns from other disciplines, such as PI3K/AKT/mTOR pathway and Hepatocyte growth factor. Gene is a subfield of Genetics that Joseph R. Testa studies.

His most cited work include:

  • Integrated genomic analyses of ovarian carcinoma (4769 citations)
  • Perturbations of the AKT signaling pathway in human cancer (1017 citations)
  • A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region (832 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cancer research, Molecular biology, Genetics, Gene and Carcinogenesis. His research in Cancer research intersects with topics in Cancer, Protein kinase B, Cell culture, Mesothelioma and Cell growth. His Protein kinase B research is multidisciplinary, incorporating elements of PI3K/AKT/mTOR pathway and PTEN.

The study incorporates disciplines such as CDKN2A, Immunology and Carcinogen in addition to Mesothelioma. His Molecular biology research incorporates elements of Gene expression, In situ hybridization, Chromosomal translocation, Complementary DNA and Fluorescence in situ hybridization. He is interested in Tumor suppressor gene, which is a field of Carcinogenesis.

He most often published in these fields:

  • Cancer research (40.21%)
  • Molecular biology (26.63%)
  • Genetics (20.37%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cancer research (40.21%)
  • Cancer (12.01%)
  • BAP1 (6.27%)

In recent papers he was focusing on the following fields of study:

Joseph R. Testa mostly deals with Cancer research, Cancer, BAP1, Mesothelioma and Pathology. His Cancer research study combines topics in areas such as Protein kinase B, Cell growth, Carcinogenesis, Downregulation and upregulation and Lymphoma. His Cancer study introduces a deeper knowledge of Genetics.

Joseph R. Testa studies Genetics, focusing on Gene in particular. His research on Mesothelioma also deals with topics like

  • CDKN2A together with Pleural Neoplasm, Cell culture and Stem cell,
  • Immunology that intertwine with fields like Carcinogen. As a member of one scientific family, Joseph R. Testa mostly works in the field of Clear cell renal cell carcinoma, focusing on Immunohistochemistry and, on occasion, Molecular biology.

Between 2013 and 2021, his most popular works were:

  • Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship (141 citations)
  • Germline Mutation of Bap1 Accelerates Development of Asbestos-Induced Malignant Mesothelioma (90 citations)
  • Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide (69 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

Joseph R. Testa mainly focuses on BAP1, Cancer research, Mesothelioma, CDKN2A and Cancer. He interconnects SETD2, Protein kinase B, Cisplatin, Cancer cell and Cancer stem cell in the investigation of issues within Cancer research. His research investigates the connection between Mesothelioma and topics such as Internal medicine that intersect with issues in Surgery and Gastroenterology.

Joseph R. Testa combines subjects such as Inflammasome, Carcinogen, Downregulation and upregulation, Pathology and Stem cell with his study of CDKN2A. His study in Pathology is interdisciplinary in nature, drawing from both Cell, AKT2 and Adenocarcinoma. Particularly relevant to Carcinogenesis is his body of work in Cancer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Integrated genomic analyses of ovarian carcinoma

D. Bell;A. Berchuck;M. Birrer;J. Chien.
Nature (2011)

5752 Citations

Perturbations of the AKT signaling pathway in human cancer

Deborah A Altomare;Joseph R Testa.
Oncogene (2005)

1509 Citations

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

A Bellacosa;Testa;SP Staal;PN Tsichlis.
Science (1991)

1334 Citations

AKT plays a central role in tumorigenesis.

Joseph R. Testa;Alfonso Bellacosa.
Proceedings of the National Academy of Sciences of the United States of America (2001)

1271 Citations

Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas.

A. Bellacosa;D. De Feo;A. K. Godwin;D. W. Bell.
International Journal of Cancer (1995)

1126 Citations

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

Jin Quan Cheng;Bruce Ruggeri;Walter M. Klein;Gonosuke Sonoda.
Proceedings of the National Academy of Sciences of the United States of America (1996)

1040 Citations

Germline BAP1 mutations predispose to malignant mesothelioma

Joseph R Testa;Mitchell Cheung;Jianming Pei;Jennifer E Below.
Nature Genetics (2011)

988 Citations

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.

Jin Quan Cheng;Andrew K. Godwin;Alfonso Bellacosa;Takahiro Taguchi.
Proceedings of the National Academy of Sciences of the United States of America (1992)

977 Citations

Activation of AKT kinases in cancer: implications for therapeutic targeting.

Alfonso Bellacosa;C. Chandra Kumar;Antonio Di Cristofano;Joseph Robert Testa.
Advances in Cancer Research (2005)

964 Citations

BAP1 and cancer

Michele Carbone;Haining Yang;Harvey I. Pass;Thomas Krausz.
Nature Reviews Cancer (2013)

555 Citations

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