World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
115
Citations
65355
World Ranking
4455
National Ranking
123

Research.com Recognitions

  • 2018 - Fellow of the Australian Academy of Science
  • 2016 - Fellow of the Australian Academy of Health and Medical Science

Overview

David D.L. Bowtell is affiliated with the Peter MacCallum Cancer Centre in Australia, focusing on research at the intersection of medicine, biochemistry, genetics, and molecular biology. Their published contributions span multiple aspects of cancer research, with a particular emphasis on ovarian cancer diagnosis and treatment, cancer genomics, and molecular mechanisms underlying cancer progression.

The scientist's research expertise includes several specialized subfields:

  • Molecular Biology
  • Reproductive Medicine
  • Oncology
  • Cancer Research
  • Genetics

Key research topics address:

  • Ovarian cancer diagnosis and treatment
  • Cancer Genomics and Diagnostics
  • PARP inhibition in cancer therapy
  • BRCA gene mutations in cancer
  • Cancer Diagnosis and Treatment
  • DNA Repair Mechanisms
  • Cancer-related molecular mechanisms research

Bowtell has contributed to several significant papers, including:

  • The evolutionary history of 2,658 cancers, 2020, Nature
  • Patterns of somatic structural variation in human cancer genomes, 2020, Nature
  • Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing, 2020, Nature Genetics
  • Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes, 2021, Cell
  • ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancer, 2020, Annals of Oncology

Frequent collaborators include:

  • Anna DeFazio
  • Dale W. Garsed
  • Sián Fereday
  • Elizabeth L. Christie
  • Nadia Traficante

Their work is also present in multiple publication venues, such as:

  • Cancer Research
  • Nature Communications
  • Clinical Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gynecologic Oncology

David D.L. Bowtell has been recognized with fellowships from prominent scientific institutions:

  • Fellow of the Australian Academy of Science, 2018
  • Fellow of the Australian Academy of Health and Medical Science, 2016

Best Publications

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • ARID1A mutations in endometriosis-associated ovarian carcinomas.

    Kimberly C. Wiegand;Sohrab P. Shah;Osama M. Al-Agha;Yongjun Zhao

  • Rethinking ovarian cancer: recommendations for improving outcomes

    Sebastian Vaughan;Jermaine I. Coward;Robert C. Bast;Andy Berchuck

  • Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome

    Richard W Tothill;Anna V Tinker;Joshy George;Robert Brown

  • Whole-genome characterization of chemoresistant ovarian cancer

    Ann-Marie Patch;Ann-Marie Patch;Elizabeth Christie;Dariush Etemadmoghadam;Dariush Etemadmoghadam;Dale W. Garsed

  • Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer

    David D. Bowtell;David D. Bowtell;Steffen Böhm;Ahmed A. Ahmed;Paul Joseph Aspuria

  • BRCA Mutation Frequency and Patterns of Treatment Response in BRCA Mutation–Positive Women With Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group

    Kathryn Alsop;Sian Fereday;Cliff Meldrum;Anna deFazio

  • Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

    Michael A. Simon;David D.L. Bowtell;G.Steven Dodson;Todd R. Laverty

  • The evolutionary history of 2,658 cancers

    Moritz Gerstung;Moritz Gerstung;Clemency Jolly;Ignaty Leshchiner;Stefan C Dentro;Stefan C Dentro;Stefan C Dentro

  • Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary

    Ahmed Ashour Ahmed;Dariush Etemadmoghadam;Jillian Temple;Andy G Lynch

  • Isolation of a Candidate Human Telomerase Catalytic Subunit Gene, Which Reveals Complex Splicing Patterns in Different Cell Types

    Andrzej Kilian;David D.L. Bowtell;Helen E. Abud;Gary R. Hime

  • Mutation of FOXL2 in Granulosa-Cell Tumors of the Ovary

    Sohrab P Shah;Martin Köbel;Janine Senz;Ryan D Morin

  • Options available — from start to finish — for obtaining expression data by microarray

    David D.L. Bowtell

  • Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

    Melissa J. Peart;Gordon K. Smyth;Ryan K. van Laar;David D. Bowtell

  • Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

    Roel G.W. Verhaak;Pablo Tamayo;Ji Yeon Yang;Diana Hubbard

  • Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway.

    Lorri Puil;Jiaxin Liu;Gerald Gish;Geraldine Mbamalu

  • 2004 consensus statements on the management of ovarian cancer: final document of the 3rd International Gynecologic Cancer Intergroup Ovarian Cancer Consensus Conference (GCIG OCCC 2004).

    A du Bois;M Quinn;T Thigpen;J Vermorken

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

Frequent Co-Authors

Susan J. Ramus
Susan J. Ramus University of New South Wales
Clare L. Scott
Clare L. Scott Walter and Eliza Hall Institute of Medical Research
Ian G. Campbell
Ian G. Campbell Peter MacCallum Cancer Centre
David G. Huntsman
David G. Huntsman University of British Columbia
Ellen L. Goode
Ellen L. Goode Mayo Clinic
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute
Paul D.P. Pharoah
Paul D.P. Pharoah University of Cambridge
Stephen B. Fox
Stephen B. Fox Peter MacCallum Cancer Centre
James D. Brenton
James D. Brenton University of Cambridge
Martin Köbel
Martin Köbel University of Calgary

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re exploring medical careers beyond traditional MD programs, there are several flexible online pathways to advance your education and credentials in the USA. Many students and working professionals are turning to online nursing programs designed to accelerate career growth or transition into new roles.

For registered nurses looking to earn a bachelor’s degree, there are online rn to bsn programs no clinicals, so you can upskill without additional clinical requirements. Those seeking advanced practice roles can explore the shortest dnp programs online or consider alternate routes like online dnp programs known for their flexible schedules and varied specialization options.

If you aim to quickly enter nursing, accelerated lpn program options online can help you start your healthcare journey faster. Whatever your goals, these online degrees offer greater accessibility, allowing you to balance studies with professional or personal commitments.

Best Scientists Citing David D.L. Bowtell

Trending Scientists