World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
124
Citations
61313
World Ranking
3209
National Ranking
1771

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary areas of study are Pathology, Serous fluid, Cancer research, Ovarian cancer and Cancer. His research integrates issues of KRAS, Serous carcinoma and Adenocarcinoma in his study of Pathology. His Serous fluid research incorporates elements of Ovarian carcinoma, Fallopian tube, Carcinoma, Cystadenocarcinoma and Cystadenoma.

His work carried out in the field of Cancer research brings together such families of science as Carcinogenesis, Mutation, ARID1A, Immunology and Fluorescence in situ hybridization. His work deals with themes such as Molecular biology, Gene dosage, Gene duplication, Gene and PTEN, which intersect with Ovarian cancer. His Cancer research is multidisciplinary, incorporating perspectives in Carboplatin, Chromosome instability and Blood plasma.

His most cited work include:

  • The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory. (1209 citations)
  • ARID1A mutations in endometriosis-associated ovarian carcinomas. (1139 citations)
  • Ovarian Tumorigenesis : A Proposed Model Based on Morphological and Molecular Genetic Analysis (967 citations)

What are the main themes of his work throughout his whole career to date?

Ie Ming Shih mainly focuses on Pathology, Cancer research, Ovarian cancer, Serous fluid and Cancer. His Pathology research integrates issues from Trophoblastic Tumor, Tumor progression and Placental site trophoblastic tumor. His Cancer research research incorporates themes from Gene knockdown, Carcinogenesis, Cancer cell and Mutation, ARID1A.

His biological study spans a wide range of topics, including Molecular biology and Oncology. In his study, which falls under the umbrella issue of Molecular biology, Computational biology is strongly linked to Gene. His work focuses on many connections between Serous fluid and other disciplines, such as Serous carcinoma, that overlap with his field of interest in Ovary.

He most often published in these fields:

  • Pathology (45.00%)
  • Cancer research (33.10%)
  • Ovarian cancer (32.14%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cancer research (33.10%)
  • Ovarian cancer (32.14%)
  • Cancer (21.19%)

In recent papers he was focusing on the following fields of study:

Ie Ming Shih focuses on Cancer research, Ovarian cancer, Cancer, Pathology and Serous fluid. His Cancer research study incorporates themes from Cancer cell, Reprogramming and Mutation. His Ovarian cancer study integrates concerns from other disciplines, such as Tumor microenvironment, Papanicolaou stain and EZH2.

The various areas that Ie Ming Shih examines in his Cancer study include Biopsy, Epigenetics and Aneuploidy. His research in Pathology intersects with topics in Personalized treatment and Bioinformatics. The Serous fluid study combines topics in areas such as Ovarian carcinoma, Computational biology and Gene.

Between 2017 and 2021, his most popular works were:

  • Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities. (142 citations)
  • Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers (86 citations)
  • The Origin and Pathogenesis of Endometriosis. (34 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His primary areas of investigation include Cancer research, Ovarian cancer, Cancer, Pathology and Ovarian carcinoma. His Cancer research research is multidisciplinary, relying on both Cancer cell, Chromatin remodeling and Immune system, Immunotherapy. His work on Serous carcinoma as part of general Ovarian cancer study is frequently linked to Progesterone receptor, bridging the gap between disciplines.

His studies deal with areas such as Gastroenterology, Aneuploidy and Esophagus as well as Cancer. His Pathology research is multidisciplinary, incorporating elements of Somatic cell, Endometrial cancer and Somatic evolution in cancer. The study incorporates disciplines such as Carcinoma, Serous fluid and Fallopian tube in addition to Ovarian carcinoma.

Best Publications

  • The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory.

    Robert J. Kurman;Ie Ming Shih

  • ARID1A mutations in endometriosis-associated ovarian carcinomas.

    Kimberly C. Wiegand;Sohrab P. Shah;Osama M. Al-Agha;Yongjun Zhao

  • Ovarian Tumorigenesis : A Proposed Model Based on Morphological and Molecular Genetic Analysis

    Ie Ming Shih;Robert J. Kurman

  • TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

    Patrick J. Killela;Zachary J. Reitman;Yuchen Jiao;Chetan Bettegowda

  • Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

    Siân Jones;Tian Li Wang;Ie Ming Shih;Tsui Lien Mao

  • Proteogenomic characterization of human colon and rectal cancer

    Bing Zhang;Jing Wang;Xiaojing Wang;Jing Zhu

  • Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer—Shifting the paradigm

    Robert J. Kurman;Ie Ming Shih

  • Mutations in BRAF and KRAS Characterize the Development of Low-Grade Ovarian Serous Carcinoma

    Gad Singer;Robert Oldt;Yoram Cohen;Brant G. Wang

  • Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer

    Hui Zhang;Tao Liu;Zhen Zhang;Samuel H. Payne

  • The Dualistic Model of Ovarian Carcinogenesis: Revisited, Revised, and Expanded.

    Robert J. Kurman;Ie Ming Shih

  • OVARIAN LOW-GRADE AND HIGH-GRADE SEROUS CARCINOMA: Pathogenesis, Clinicopathologic and Molecular Biologic Features, and Diagnostic Problems

    Russell Vang;Ie Ming Shih;Robert J. Kurman

  • Pathogenesis of ovarian cancer: lessons from morphology and molecular biology and their clinical implications.

    Robert J. Kurman;Ie Ming Shih

  • High grade serous ovarian carcinomas originate in the fallopian tube

    S. Intidhar Labidi-Galy;S. Intidhar Labidi-Galy;Eniko Papp;Dorothy Hallberg;Noushin Niknafs;Noushin Niknafs

  • Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A -mutated cancers

    Benjamin G. Bitler;Katherine M. Aird;Azat Garipov;Hua Li

  • The role of chromosomal instability in tumor initiation.

    Martin A. Nowak;Natalia L. Komarova;Anirvan Sengupta;Prasad V. Jallepalli

  • Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities.

    Suhas Vasaikar;Chen Huang;Xiaojing Wang;Vladislav A. Petyuk

  • Cancer-Associated Mutations in Endometriosis without Cancer

    Michael S. Anglesio;Nickolas Papadopoulos;Ayse Ayhan;Tayyebeh M. Nazeran

  • Immunohistochemical staining patterns of p53 can serve as a surrogate marker for TP53 mutations in ovarian carcinoma: an immunohistochemical and nucleotide sequencing analysis

    Anna Yemelyanova;Russell Vang;Malti Kshirsagar;Dan Lu

  • National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for Use of Tumor Markers in Testicular, Prostate, Colorectal, Breast, and Ovarian Cancers

    Catharine M. Sturgeon;Michael J. Duffy;Ulf Håkan Stenman;Hans Lilja

  • TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL

    Hai Yan;P.J. Killela;Z.J. Reitman;Y. Jiao

Frequent Co-Authors

Tian Li Wang
Tian Li Wang Johns Hopkins University
Robert J. Kurman
Robert J. Kurman Johns Hopkins University
Ben Davidson
Ben Davidson Oslo University Hospital
Yue Wang
Yue Wang Zhejiang University
Douglas A. Levine
Douglas A. Levine New York University
Robert Clarke
Robert Clarke University of Oxford
Bert Vogelstein
Bert Vogelstein Johns Hopkins University
Daniel W. Chan
Daniel W. Chan Johns Hopkins University School of Medicine
Kenneth W. Kinzler
Kenneth W. Kinzler Johns Hopkins University
Nickolas Papadopoulos
Nickolas Papadopoulos Johns Hopkins University School of Medicine

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