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Biology and Biochemistry

D-Index
59
Citations
10133
World Ranking
12774
National Ranking
5446

Overview

Douglas J. Taatjes is a researcher affiliated with the University of Vermont in the United States. Their work spans several fields within the life sciences, with a particular focus on biochemistry, genetics, molecular biology, and medicine.

The primary subfields of study in Taatjes's research include molecular biology, cancer research, oncology, biophysics, and pulmonary and respiratory medicine. Their investigations cover a broad range of topics, notably:

  • Cancer, hypoxia, and metabolism
  • Epigenetics and DNA methylation
  • Cancer genomics and diagnostics
  • Cell image analysis techniques
  • Ubiquitin and proteasome pathways
  • Cancer-related molecular pathways
  • Immune cells in cancer

Taatjes has contributed extensively to scientific literature. Their recent papers include:

  • "Community-developed checklists for publishing images and image analyses," 2023, Nature Methods
  • "Nanoscale imaging using differential expansion microscopy," 2020, Histochemistry and Cell Biology
  • "Dysregulation of Pyruvate Kinase M2 Promotes Inflammation in a Mouse Model of Obese Allergic Asthma," 2021, American Journal of Respiratory Cell and Molecular Biology
  • "Comparative immunogenicity of decellularized wild type and alpha 1,3 galactosyltransferase knockout pig lungs," 2021, Biomaterials
  • "Glutaredoxin deficiency promotes activation of the transforming growth factor beta pathway in airway epithelial cells, in association with fibrotic airway remodeling," 2020, Redox Biology

Their frequent coauthors include Jürgen Roth, Roxanna Barnaby, Bruce A. Stanton, Bhanu P. Jena, and Amanda Nymon.

Taatjes's work is regularly published in several journals. The most frequent publication venues are:

  • Histochemistry and Cell Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biomolecular Techniques JBT
  • American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Journal of Cystic Fibrosis

Best Publications

  • Demonstration of an extensive trans-tubular network continuous with the Golgi apparatus stack that may function in glycosylation

    Jürgen Roth;Douglas J. Taatjes;John M. Lucocq;Jasminder Weinstein

  • Morphological and cytochemical determination of cell death by apoptosis

    Douglas J. Taatjes;Burton E. Sobel;Ralph C. Budd

  • Reexpression of poly(sialic acid) units of the neural cell adhesion molecule in Wilms tumor.

    Jurgen Roth;Christian Zuber;Philipp Wagner;Douglas J. Taatjes

  • Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drug.

    Jacob H. Rand;Xiao-Xuan Wu;Anthony S. Quinn;Anthony W. Ashton

  • Hydroxychloroquine directly reduces the binding of antiphospholipid antibody–β2-glycoprotein I complexes to phospholipid bilayers

    Jacob H. Rand;Xiao-Xuan Wu;Anthony S. Quinn;Pojen P. Chen

  • Human monoclonal antiphospholipid antibodies disrupt the annexin A5 anticoagulant crystal shield on phospholipid bilayers: evidence from atomic force microscopy and functional assay.

    Jacob H. Rand;Xiao Xuan Wu;Anthony S. Quinn;Pojen P. Chen

  • NF-κB Activation in Airways Modulates Allergic Inflammation but Not Hyperresponsiveness

    Matthew E. Poynter;Roy Cloots;Tiest van Woerkom;Kelly J. Butnor

  • Group V Secretory Phospholipase A2 Promotes Atherosclerosis: Evidence From Genetically Altered Mice

    Meredith A. Bostrom;Boris B. Boyanovsky;Craig T. Jordan;Marilyn P. Wadsworth

  • The annexin A5-mediated pathogenic mechanism in the antiphospholipid syndrome: role in pregnancy losses and thrombosis

    Rand Jh;Wu Xx;Quinn As;Taatjes Dj

  • Cardiac myofibroblasts express alpha smooth muscle actin during right ventricular pressure overload in the rabbit.

    K. O. Leslie;D. J. Taatjes;J. Schwarz;M. vonTurkovich

  • Fibroblasts form a body-wide cellular network

    Helene M. Langevin;Carson J. Cornbrooks;Douglas J. Taatjes

  • Intramural Plasminogen Activator Inhibitor Type-1 and Coronary Atherosclerosis

    Burton E. Sobel;Douglas J. Taatjes;David J. Schneider

  • Increased epidermal growth factor-receptor protein in a human mesothelial cell line in response to long asbestos fibers.

    J.-C. Pache;Y. M. W. Janssen;E. S. Walsh;T. R. Quinlan

  • Valves of the deep venous system: an overlooked risk factor

    Erin G. Brooks;Winifred Trotman;Marilyn P. Wadsworth;Douglas J. Taatjes

  • Post-Golgi apparatus localization and regional expression of rat intestinal sialyltransferase detected by immunoelectron microscopy with polypeptide epitope-purified antibody.

    D J Taatjes;J Roth;J Weinstein;J C Paulson

  • Apoptosis is observed in mesothelial cells after exposure to crocidolite asbestos.

    Kelly Ann Berube;T. R. Quinlan;H. Fung;J. Magae

  • Different Accumulation of Activated Extracellular Signal–Regulated Kinases (ERK 1/2) and Role in Cell-Cycle Alterations by Epidermal Growth Factor, Hydrogen Peroxide, or Asbestos in Pulmonary Epithelial Cells

    Sylke Buder-Hoffmann;Cathy Palmer;Pamela Vacek;Douglas Taatjes

  • Beta 1,4-galactosyltransferase: a short NH2-terminal fragment that includes the cytoplasmic and transmembrane domain is sufficient for Golgi retention.

    R N Russo;N L Shaper;D J Taatjes;J H Shaper

  • Polysialic acid units are spatially and temporally expressed in developing postnatal rat kidney

    Jurgen Roth;Douglas J. Taatjes;Dieter Bitter-Suermann;Jukka Finne

  • Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosis

    Arti Shukla;Michael Jung;Maria Stern;Naomi K. Fukagawa

Frequent Co-Authors

Burton E. Sobel
Burton E. Sobel Washington University in St. Louis
Jürgen Roth
Jürgen Roth University of Zurich
Yvonne M. W. Janssen-Heininger
Yvonne M. W. Janssen-Heininger University of Vermont
Mercedes Rincon
Mercedes Rincon University of Vermont
Albert van der Vliet
Albert van der Vliet University of Vermont
Jacob H. Rand
Jacob H. Rand Cornell University
Nicholas H. Heintz
Nicholas H. Heintz University of Vermont
Charles G. Irvin
Charles G. Irvin University of Vermont
Matthew E. Poynter
Matthew E. Poynter University of Vermont
Ralph C. Budd
Ralph C. Budd University of Vermont

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